慢性HBV携带者肝脏病理与五行体质及中医证型的相关性研究
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摘要
目的探讨慢性乙型肝炎病毒(HBV)携带者肝脏病理与五行体质及中医证型的相关性。方法选取2016年7月—2018年4月我院200例慢性HBV携带者,均行肝穿刺检查、五行体质辨识及中医辨证分型,比较肝脏病理与五行体质及中医证型构成情况。结果 G0、G1级木型、火型所占比例高于G2+G3级,土型、水型所占比例低于G2+G3级,差异有统计学意义(P<0.05);S0、S1级木型、火型所占比例高于S2+S3级,土型低于S2+S3级,差异有统计学意义(P<0.05);G0、G1与G2+G3患者中医证型构成情况比较,差异无统计学意义(P>0.05);S0、S1与S2+S3患者中医证型构成情况比较,差异无统计学意义(P>0.05)。结论随着慢性HBV携带者肝脏炎症分级纤维化分级加重五行体质也随之发生变化,故可通过对患者五行体质观察间接评价患者肝脏病理组织炎症及纤维化情况。
Objective To study the relationship between liver pathology,five elements constitution and TCM syndrome type of chronic hepatitis B virus carriers. Methods 200 cases of chronic HBV carriers in our hospital from July 2016 to April 2018 were selected for liver puncture examination,five elements constitution identification and TCM syndrome differentiation,and the liver pathology was compared with the constitution of five elements constitution and TCM syndromes. Results The ratio of fire type was higher than that of G 2 + G 3 type,and the proportion of soil type and water type was lower than that of G2 + G 3 class. The difference was statistically significant( P < 0. 05). The proportion of fire type was higher than that of fire type. At S2 + S3,soil type was lower than S 2 + S 3,the difference was statistically significant( P < 0. 05). There was no significant difference between G2 + G3 and G0,G1( P > 0. 05). There was no significant difference in TCM syndrome composition between S0,S1 and S2 + S3( P > 0. 05). Conclusion with the exacerbation of liver inflammation and fibrosis grading in chronic HBV carriers,the constitution of the five elements is also changed,so the pathological tissue inflammation and fibrosis of the liver can be indirectly evaluated by observing the constitution of the five elements of the patients.
Objective To study the relationship between liver pathology,five elements constitution and TCM syndrome type of chronic hepatitis B virus carriers. Methods 200 cases of chronic HBV carriers in our hospital from July 2016 to April 2018 were selected for liver puncture examination,five elements constitution identification and TCM syndrome differentiation,and the liver pathology was compared with the constitution of five elements constitution and TCM syndromes. Results The ratio of fire type was higher than that of G 2 + G 3 type,and the proportion of soil type and water type was lower than that of G2 + G 3 class. The difference was statistically significant( P < 0. 05). The proportion of fire type was higher than that of fire type. At S2 + S3,soil type was lower than S 2 + S 3,the difference was statistically significant( P < 0. 05). There was no significant difference between G2 + G3 and G0,G1( P > 0. 05). There was no significant difference in TCM syndrome composition between S0,S1 and S2 + S3( P > 0. 05). Conclusion with the exacerbation of liver inflammation and fibrosis grading in chronic HBV carriers,the constitution of the five elements is also changed,so the pathological tissue inflammation and fibrosis of the liver can be indirectly evaluated by observing the constitution of the five elements of the patients.
引文
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[4]姚乃礼.中医证候鉴别诊断学[M].北京:人民卫生出版社,2005:2.
[5]解观月,孙建光.慢性HBV携带者中医证型及体质的研究进展[J].中西医结合肝病杂志,2016,26(2):128-附Ⅰ.
[6]刘乐鑫,池晓玲,林姗姗,等.慢性HBV携带者肝脏病理与五行体质及中医证型的相关性探讨[J].中医药学报,2016,44(6):19-22.
[7]王淑云.常规易测检验指标与慢性乙肝中医证型的相关性分析[J].光明中医,2018,33(1):17-19.