突发性耳聋的发病机制
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摘要
突发性耳聋是一种突发的原因不明的感音神经性耳聋,其病因及病理学机制具体尚未阐明,局部或全身因素均可能引起突发性耳聋,目前最常见的病因机制有血管性疾病、病毒感染学说、自身免疫性疾病、内淋巴积水等其他可能原因。本文将对近几年众多学者对突发性耳聋病因机制研究成果做一简单综诉。
Sudden sensorneual hearing loss is a sudden and unexplained sensorineural hearing loss,its etiology and pathology mechanism has not been clarified,both partial and systemic factors could cause sudden sensorneual hearing loss.At present,the most common etiological mechanisms are vascular diseases,viral infection theory,autoimmune diseases,endolymphatic hydrops and other possible causes.In this paper,the achievement on the pathogenesis of sudden sensorneual hearing loss researched by a large number of scholars in recent years is about to be introduced.
Sudden sensorneual hearing loss is a sudden and unexplained sensorineural hearing loss,its etiology and pathology mechanism has not been clarified,both partial and systemic factors could cause sudden sensorneual hearing loss.At present,the most common etiological mechanisms are vascular diseases,viral infection theory,autoimmune diseases,endolymphatic hydrops and other possible causes.In this paper,the achievement on the pathogenesis of sudden sensorneual hearing loss researched by a large number of scholars in recent years is about to be introduced.
引文
[1]Stew BT,Fishpool SJC,Williams H.Sudden Sensorineural hearing loss.Br J Hosp Med.2012;73(2):86-89
[2]Leung M A,Flaherty A,Zhang J A,et al.Sudden Sensorineural Hearing Loss:Primary Care Update[J].Hawaii Journal of Medicine&Public Health A Journal of Asia Pacific Medicine&Public Health,2016;75(6):172
[3]李学佩,马芙蓉.椎基底动脉供血障碍时内耳微循环的变化及其调节[J].中国耳鼻咽喉颅底外科杂志,1996;(3):135-138
[4]Mohsen R,Reza A M,Mohsen M,et al.Is Sudden Hearing Loss Associated with Atherosclerosis?[J].Iranian Journal of Otorhinolaryngology,2016;28(86):189-195
[5]唐德萍,唐德斌,朱秋梅,等.突发性耳聋的脑血流动力学研究[J].广西医学,2012;34(8):987-988
[6]Mohammed A A M.Lipid Profile among Patients with Sudden Sensorineural Hearing Loss[J].Indian Journal of Otolaryngology&Head&Neck Surgery Official Publication of the Association of Otolaryngologists of India,2014;66(4):425
[7]Gül,F.,Ber9in,S.,Müderris,T.,et al.Unilateral sudden hearing loss:a rare symptom of moyamoya disease.Kulak burun bogaz ihtisas dergisi[J].KBB=Journal of ear,nose,and throat,2016;26(2):114
[8]Ulu,S.,Ulu,M.S.,Ahsen,A.,et al.Increased levels of mean platelet volume:apossible relationship with idiopathic sudden hearing loss[J].European Archives of Oto-Rhino-Laryngology,2013;270(11):2875-2878
[9]Mirvakili,A.,Dadgarnia,M.H.,Baradaranfar,M.H.,et al.Role of platelet parameters on sudden sensorineural hearing loss:a case-control study in iran[J].Plos One,2016;11(2):e0148149
[10]Kyung-Hwa,J.,Woo,C.J.,Eun,S.J.,et al.Abnormal magnetic resonance imaging findings in patients with sudden sensorineural hearing loss:vestibular schwannoma as the most common cause of mri abnormality[J].Medicine,2016;95(17):e3557
[11]Kharbanda,R.K.,Deanfield,J.E.Functions of the healthy endothelium[J].Coronary Artery Disease,2001;12(6):485
[12]Nezamoddin,B.,Maryam,M.,Mostafa,H.S.,et al.Endothelial dysfunction in patients with sudden sensorineural hearing loss[J].Advanced Biomedical Research,2016;5(1):5
[13]施典羽,杨凯,敬光怀,等.特发性突聋患者外周血et、cgrp和no的检测分析[J].中国中西医结合耳鼻咽喉科杂志2012;20(4):246-248
[14]施典羽,杨凯,敬光怀,等.(2011).特发性突聋患者外周血no的变化[J].河北医学,2011;17(1):31-34
[15]Quaranta N,Ceglie V D,D’Elia A.Endothelial Dysfunction in Idiopathic Sudden Sensorineural Hearing Loss:A Review[J].Audiology Research,2016,6(1):187-193
[16]刘颖,曹代荣,方哲明,等.伴眩晕突发性耳聋患者内耳外淋巴液增强mri特征[J].中华放射学杂志,2014;48(12),996-999
[17]赵鹏举,刘阳,王庆军,等.突发性耳聋患者内淋巴积水的客观影像检测[J].中华耳科学杂志,2016;14(6):764-768
[18]张呈辉,刘伟,张志钢,等.突发性聋患者耳蜗电图分析[J].听力学及言语疾病杂志,2007;15(3):192-194
[19]李和清,任基浩,卢永德.突聋血清病毒特异性igm抗体及no检测的初步研究[J].中国耳鼻咽喉颅底外科杂志,2002;8(2):133-134
[20]刘瑶,管国芳,孙开.突发性耳聋与巨细胞病毒感染关系初探[J].吉林医学,2011;32(13):2513-2514
[21]Chen,H.C.,Chung,C.H.,Wang,C.H.,et al.Increased risk of sudden sensorineural hearing loss in patients with hepatitis virus infection[J].Plos One,2017;12(4):e0175266
[22]Bhavana,K.,Tyagi,I.,Kapila,R.K.Chikungunya virus induced sudden sensorineural hearing loss[J].International Journal of Pediatric Otorhinolaryngology,2008;72(2):257-259
[23]Rossini,B.A.A.,Penido,N.D.O.,et al.Sudden sensorioneural hearing loss and autoimmune systemic diseases[J].Int Arch Otorhinolaryngol,2017;21(3):213-223
[24]Rajati,M.,Saghafi,M.,Rafatpanah,H.,et al.Immunology-rheumatology approach to sudden sensorineural hearing loss[J].Current Rheumatology Reviews,2016;14(1):237-242
[25]9zler GS.Increased neutrophil-lymphocyte ratio in patients with idiopathic sudden sensorineural hearing loss[J].Journal of Craniofacial Surgery,2014;25(3):260-3
[26]唐艳艳.突发性耳聋患者血清NO、免疫球蛋白、SOD及LOP水平检测意义研究[J].河南医学研究,2017;26(1):48-49
[27]陈宏,齐国荣,张学艳,等.心理状态及微循环障碍与突发性耳聋的相关性研究[J].山西医药杂志,2016;45(8):953-955
[28]Lin,C.S.,Lin,Y.S.,Liu,C.F.,et al.Increased risk of sudden sensorineural hearing loss in patients with depressive disorders:population-based cohort study[J].Journal of Laryngology&Otology,2015;130(1),42-49
[2]Leung M A,Flaherty A,Zhang J A,et al.Sudden Sensorineural Hearing Loss:Primary Care Update[J].Hawaii Journal of Medicine&Public Health A Journal of Asia Pacific Medicine&Public Health,2016;75(6):172
[3]李学佩,马芙蓉.椎基底动脉供血障碍时内耳微循环的变化及其调节[J].中国耳鼻咽喉颅底外科杂志,1996;(3):135-138
[4]Mohsen R,Reza A M,Mohsen M,et al.Is Sudden Hearing Loss Associated with Atherosclerosis?[J].Iranian Journal of Otorhinolaryngology,2016;28(86):189-195
[5]唐德萍,唐德斌,朱秋梅,等.突发性耳聋的脑血流动力学研究[J].广西医学,2012;34(8):987-988
[6]Mohammed A A M.Lipid Profile among Patients with Sudden Sensorineural Hearing Loss[J].Indian Journal of Otolaryngology&Head&Neck Surgery Official Publication of the Association of Otolaryngologists of India,2014;66(4):425
[7]Gül,F.,Ber9in,S.,Müderris,T.,et al.Unilateral sudden hearing loss:a rare symptom of moyamoya disease.Kulak burun bogaz ihtisas dergisi[J].KBB=Journal of ear,nose,and throat,2016;26(2):114
[8]Ulu,S.,Ulu,M.S.,Ahsen,A.,et al.Increased levels of mean platelet volume:apossible relationship with idiopathic sudden hearing loss[J].European Archives of Oto-Rhino-Laryngology,2013;270(11):2875-2878
[9]Mirvakili,A.,Dadgarnia,M.H.,Baradaranfar,M.H.,et al.Role of platelet parameters on sudden sensorineural hearing loss:a case-control study in iran[J].Plos One,2016;11(2):e0148149
[10]Kyung-Hwa,J.,Woo,C.J.,Eun,S.J.,et al.Abnormal magnetic resonance imaging findings in patients with sudden sensorineural hearing loss:vestibular schwannoma as the most common cause of mri abnormality[J].Medicine,2016;95(17):e3557
[11]Kharbanda,R.K.,Deanfield,J.E.Functions of the healthy endothelium[J].Coronary Artery Disease,2001;12(6):485
[12]Nezamoddin,B.,Maryam,M.,Mostafa,H.S.,et al.Endothelial dysfunction in patients with sudden sensorineural hearing loss[J].Advanced Biomedical Research,2016;5(1):5
[13]施典羽,杨凯,敬光怀,等.特发性突聋患者外周血et、cgrp和no的检测分析[J].中国中西医结合耳鼻咽喉科杂志2012;20(4):246-248
[14]施典羽,杨凯,敬光怀,等.(2011).特发性突聋患者外周血no的变化[J].河北医学,2011;17(1):31-34
[15]Quaranta N,Ceglie V D,D’Elia A.Endothelial Dysfunction in Idiopathic Sudden Sensorineural Hearing Loss:A Review[J].Audiology Research,2016,6(1):187-193
[16]刘颖,曹代荣,方哲明,等.伴眩晕突发性耳聋患者内耳外淋巴液增强mri特征[J].中华放射学杂志,2014;48(12),996-999
[17]赵鹏举,刘阳,王庆军,等.突发性耳聋患者内淋巴积水的客观影像检测[J].中华耳科学杂志,2016;14(6):764-768
[18]张呈辉,刘伟,张志钢,等.突发性聋患者耳蜗电图分析[J].听力学及言语疾病杂志,2007;15(3):192-194
[19]李和清,任基浩,卢永德.突聋血清病毒特异性igm抗体及no检测的初步研究[J].中国耳鼻咽喉颅底外科杂志,2002;8(2):133-134
[20]刘瑶,管国芳,孙开.突发性耳聋与巨细胞病毒感染关系初探[J].吉林医学,2011;32(13):2513-2514
[21]Chen,H.C.,Chung,C.H.,Wang,C.H.,et al.Increased risk of sudden sensorineural hearing loss in patients with hepatitis virus infection[J].Plos One,2017;12(4):e0175266
[22]Bhavana,K.,Tyagi,I.,Kapila,R.K.Chikungunya virus induced sudden sensorineural hearing loss[J].International Journal of Pediatric Otorhinolaryngology,2008;72(2):257-259
[23]Rossini,B.A.A.,Penido,N.D.O.,et al.Sudden sensorioneural hearing loss and autoimmune systemic diseases[J].Int Arch Otorhinolaryngol,2017;21(3):213-223
[24]Rajati,M.,Saghafi,M.,Rafatpanah,H.,et al.Immunology-rheumatology approach to sudden sensorineural hearing loss[J].Current Rheumatology Reviews,2016;14(1):237-242
[25]9zler GS.Increased neutrophil-lymphocyte ratio in patients with idiopathic sudden sensorineural hearing loss[J].Journal of Craniofacial Surgery,2014;25(3):260-3
[26]唐艳艳.突发性耳聋患者血清NO、免疫球蛋白、SOD及LOP水平检测意义研究[J].河南医学研究,2017;26(1):48-49
[27]陈宏,齐国荣,张学艳,等.心理状态及微循环障碍与突发性耳聋的相关性研究[J].山西医药杂志,2016;45(8):953-955
[28]Lin,C.S.,Lin,Y.S.,Liu,C.F.,et al.Increased risk of sudden sensorineural hearing loss in patients with depressive disorders:population-based cohort study[J].Journal of Laryngology&Otology,2015;130(1),42-49