中空多孔硫化镍立方体电化学传感检测多巴胺
|
摘要
以Ni-Co普鲁士蓝类似物为前驱体通过水热法在高温条件下利用碱性化学蚀刻和柯肯达尔效应的离子交换制备了中空多孔纳米硫化镍立方体,采用扫描透射电镜对材料进行表征。利用滴涂法制备基于中空多孔纳米硫化镍立方体修饰电极,用此电化学传感器建立了多巴胺定量检测方法。在最佳条件下,多巴胺溶液浓度在2～300μmol/L范围内与峰电流呈线性关系,r2=0. 9914,检出限为0. 68μmol/L。对尿液中多巴胺的含量进行了检测,样品加标回收率为99. 5%～103. 0%,RSD <5. 0%。方法可用于人体尿液、血清等样品中多巴胺的检测。
In this paper,hollow porous nickel sulfide nanocubes( Ni S) were prepared using a solvothermal method in which Ni-Co prussian blue analogue( PBA) nanocubes were employed as a template. During the reaction,Ni-Co PBA nanocubes were gradually converted to nickel sulfide nanocubes with a hollow porous structure through ion exchange and chemical etching. Field emission scanning electron microscope was used to characterize the structure of Ni S nanocubes. Subsequently,Ni S nanocubes were used to build an electrochemical sensor for the determination of dopamine. Under the optimal condition, dopamine had a good linear relationship between peak current and its concentration within 2-300 μmol/L with r2= 0. 9914. The limit of detection was 0. 68 μmol/L.Furthermore,urine samples were determined by the electrochemical sensor,and the recoveries were99. 5%-103. 0% with a low relative standard deviation less than 5. 0%. This method was applied for detecting dopamine in human urine and serum samples.
In this paper,hollow porous nickel sulfide nanocubes( Ni S) were prepared using a solvothermal method in which Ni-Co prussian blue analogue( PBA) nanocubes were employed as a template. During the reaction,Ni-Co PBA nanocubes were gradually converted to nickel sulfide nanocubes with a hollow porous structure through ion exchange and chemical etching. Field emission scanning electron microscope was used to characterize the structure of Ni S nanocubes. Subsequently,Ni S nanocubes were used to build an electrochemical sensor for the determination of dopamine. Under the optimal condition, dopamine had a good linear relationship between peak current and its concentration within 2-300 μmol/L with r2= 0. 9914. The limit of detection was 0. 68 μmol/L.Furthermore,urine samples were determined by the electrochemical sensor,and the recoveries were99. 5%-103. 0% with a low relative standard deviation less than 5. 0%. This method was applied for detecting dopamine in human urine and serum samples.
引文
[1] McHugh P C,Buckley D A. Vitam&Horm,2015,98:339
[2] Sajid M,Nazal M K,Mansha M,et al. Tr AC Trend Anal Chem,2016,76:15
[3] Shen J,Sun C M,Wu X. Talanta,2017,165:369
[4] Leng Y M,Xie K,Ye L Q,et al. Talanta,2015,139(1):89
[5] Park S J,Lee S H,Yang H,et al. ACS Appl Mater Interfaces,2016,8(42):28897
[6] Bandodkar A J,Wang J. Trends Biotechnol,2014,32(7):363
[7] Yan X Y,Gu Y,Li C,et al. Biosens Bioelectron,2016,77:1032
[8] Zhang C Z,Wang L W,Lu Y K,et al. Chinese J Anal Chem,2016,44(8):1263张翠忠,王丽伟,卢永课,等.分析化学,2016,44(8):1263
[9] Yang Q,Xu Q,Jiang H. Chem Soc Rev,2017,46(15):4774
[10] Liu J,Fan F,Feng Z,et al. J Phys Chem C,2008,112(4):16445
[11] Joo J B,Zhang Q,Dahl M,et al. Energ Environ Sci,2012,5(42):6321
[12] Hu J,Chen M,Fang X,et al. Chem Soc Rev,2011,40(11):5472
[13] Radhakrishnan S,Kim S J. RSC Adv,2015,5(55):44346
[14] Wu W Q,Yu B B,Jin J Y,et al. Sens Actuators B,2016,232:633
[15] Wei C Z,Cheng C,Cheng Y Y,et al. Dalton Transactions,2015,44(39):17278
[16] Du J,Ma L,Shan D,et al. J Electroanal Chem,2014,s 722-723(1):38
[2] Sajid M,Nazal M K,Mansha M,et al. Tr AC Trend Anal Chem,2016,76:15
[3] Shen J,Sun C M,Wu X. Talanta,2017,165:369
[4] Leng Y M,Xie K,Ye L Q,et al. Talanta,2015,139(1):89
[5] Park S J,Lee S H,Yang H,et al. ACS Appl Mater Interfaces,2016,8(42):28897
[6] Bandodkar A J,Wang J. Trends Biotechnol,2014,32(7):363
[7] Yan X Y,Gu Y,Li C,et al. Biosens Bioelectron,2016,77:1032
[8] Zhang C Z,Wang L W,Lu Y K,et al. Chinese J Anal Chem,2016,44(8):1263张翠忠,王丽伟,卢永课,等.分析化学,2016,44(8):1263
[9] Yang Q,Xu Q,Jiang H. Chem Soc Rev,2017,46(15):4774
[10] Liu J,Fan F,Feng Z,et al. J Phys Chem C,2008,112(4):16445
[11] Joo J B,Zhang Q,Dahl M,et al. Energ Environ Sci,2012,5(42):6321
[12] Hu J,Chen M,Fang X,et al. Chem Soc Rev,2011,40(11):5472
[13] Radhakrishnan S,Kim S J. RSC Adv,2015,5(55):44346
[14] Wu W Q,Yu B B,Jin J Y,et al. Sens Actuators B,2016,232:633
[15] Wei C Z,Cheng C,Cheng Y Y,et al. Dalton Transactions,2015,44(39):17278
[16] Du J,Ma L,Shan D,et al. J Electroanal Chem,2014,s 722-723(1):38