摘要
目的探讨体质量指数(body mass index,BMI)对青少年24 h眼压波动的影响。方法本研究共纳入90名健康青少年。采用Goldmann压平式眼压计测量受试者24 h眼压波动(5∶00 am、7∶00 am、10∶00 am、2∶00 pm、6∶00 pm、10∶00 pm)。BMI通过体质量(kg)除以身高(m)的平方计算。根据BMI将受试者分为低体质量及正常组(BMI<25 kg·m~(-2))50人,超重组(25 kg·m~(-2)≤BMI<30 kg·m~(-2))22人和肥胖组(BMI≥30 kg·m~(-2))18人。使用SPSS 22.0统计软件对测量值进行统计学分析。结果所有观察对象平均眼压、眼压峰值、眼压谷值和眼压波动值分别为(16.72±3.30)mm Hg(1 k Pa=7.5 mm Hg)、(19.26±3.68)mm Hg、(14.29±3.26)mm Hg和(4.98±1.91)mm Hg。3组间眼压波动值差异比较无统计学意义(均为P>0.05)。低体质量及正常组与肥胖组间平均眼压、眼压峰值和眼压谷值差异比较有统计学意义(均为P<0.05),而低体质量及正常组与超重组、超重组与肥胖组差异比较无统计学意义(均为P>0.05)。Pearson相关分析结果显示,BMI与平均眼压、眼压峰值呈显著正相关(P<0.05)。结论在青少年人群中,BMI较高者具有更高的平均眼压、眼压峰值。
Objective To investigate the effects of body mass index( BMI) on 24-hour intraocular pressure( IOP) fluctuations in adolescences. Methods Totally 90 healthy adolescences were included in the study. Measurements of 24-hour IOP were obtained by Goldmann applanation tonometer on 5∶00 am,7∶00 am,10∶00 am,2∶00 pm,6∶00 pm and 10∶00 pm.BMI was calculated as weight in kilograms divided by the square of height in meters( kg ·m~(-2)). The patients were divided into three groups according to BMI,and they were Group 1( BMI < 25 kg·m~(-2)),Group 2( 25≤BMI < 30 kg·m~(-2)),Group 3( BMI≥30 kg·m~(-2)). Data were analyzed by statistic software SPSS 22. 0. Results The mean of IOP,peak IOP,valley IOP and fluctuation value of IOP were( 16. 72 ± 3. 30) mm Hg( 1 k Pa = 7. 5 mm Hg),( 19. 26 ±3. 68) mm Hg,( 14. 29 ± 3. 26) mm Hg and( 4. 98 ± 1. 91) mm Hg,respectively. And there was no significant differences in the fluctuation value of IOP among the three groups( all P > 0. 05); the differences in mean IOP,peak IOP,valley IOP between group 1 and group 3 were significant( all P < 0. 05). However,the differences between group 1 and group 2,group 2 and group 3 showed no significant differences( all P > 0. 05). Pearson correlation analysis showed that BMI was positively correlated with mean IOP and peak IOP( both P < 0. 05). Conclusion In the adolescent population,individuals with higher BMI tend to have higher mean IOP and peak IOP.
引文
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