林蛙皮、卵活性成分提取方法及药理作用的研究进展
|
摘要
林蛙皮、卵中含有多种对人体有益的活性成分,对其深入研究有利于林蛙资源的综合利用.本文对林蛙皮、卵的主要活性成分提取方法及药理作用进行综述,为其在药品、保健品、化妆品等大健康领域的开发利用提供参考.
There are plenty of beneficial elements for human being in the skin and egg of Rana chensinensis,which deserved to be further studied in terms of development and utilization of genus Rana chensinensis.In this paper,the active ingredient extraction methods and pharmacological effects of skin and egg from Rana chensinensis( SERC) were reviewed,which may provide some evidences for the research and development of SERC in the fields of drug,functional food,and cosmetics.
There are plenty of beneficial elements for human being in the skin and egg of Rana chensinensis,which deserved to be further studied in terms of development and utilization of genus Rana chensinensis.In this paper,the active ingredient extraction methods and pharmacological effects of skin and egg from Rana chensinensis( SERC) were reviewed,which may provide some evidences for the research and development of SERC in the fields of drug,functional food,and cosmetics.
引文
[1]李妍妍,郑卫星,王昕,等.林蛙营养成分的多元分析[J].食品科学,2007,28(12):472-475.
[2]沈雪,崔浩,杨秀东,等.林蛙油水溶性蛋白质的制备与相对分子量测定[J].吉林化工学院学报,2016,33(9):11-14.
[3] Zhang Y,Liu Y,Zhu K,et al.Acute Toxicity,Antioxi-dant,and Antifatigue Activities of Protein-Rich Extractfrom Oviductus ranae[J].Oxidative Medicine and Cel-lular Longevity,2018(21):1-14.
[4]郑淼,周亚丹,赵敏.东北林蛙皮中胶原蛋白含量的测定及提取工艺[J].东北林业大学学报,2008,36(7):81-83.
[5]吕玲玲,金香淑,施溯筠.林蛙皮胶原蛋白的提取及抗氧化性[J].食品研究与开发,2013(10):20-22.
[6]李永政,胡春晓,王铮,等.东北林蛙卵蛋白酶解工艺及其酶解物的抗疲劳活性[J].食品科学,2012,33(9):235-239.
[7]季晓枫,林凤,邱芳萍.响应面法优化水酶法提取林蛙卵蛋白[J].长春工业大学学报(自然科学版),2013,34(2):137-144.
[8]陶凤云,赵伟,林强,等.中国林蛙卵核糖核酸酶的分离纯化及其抗肿瘤作用[J].中国生物工程杂志,2010,30(5):103-109.
[9] Wang Z,Zhao Y,Su T. Extraction and antioxidantactivity of polysaccharides fromRana chensinensis skin[J].Carbohydr Polym,2015,115(115):25-31.
[10]赵玉红,赵小旭,姜晓青.超声波-双酶法协同提取林蛙皮多糖的工艺优化[J].食品工业科技,2012,33(11):230-234.
[11]陈大勇,杨靖,李硕,等.林蛙卵多糖的提取工艺及其抗氧化作用研究[J].西北农林科技大学学报(自然科学版),2013(12):149-154.
[12]侯召华,金春爱,孙晓东,等.蛙类皮肤生物活性肽的研究进展[J].食品科技,2013(5):260-264.
[13] Zhang X,Cheng Y,Yang Y,et al.Polypeptides from theSkin ofRana Chensinensis Exert the Antioxidant andAntiapoptotic Activities on Ha Ca T cells[J].Animal Bi-otechnology,2017,28(1):1-10.
[14]杨闯,王俊玲,张传军,等.林蛙皮生物活性肽3种提取方法的比较研究[J].黑龙江畜牧兽医,2015(5):174-235.
[15] Shang D,Wang C,Wei S,et al. Membrane interactionand antibacterial properties of chensinin-1,an antimi-crobial peptide with atypical structural features fromthe skin ofRana chensinensis[J]. Appl. Microbiol. Bio-technol,2012,96(6):1551-1560.
[16] Shang D,Li X,Sun Y,et al. Design of Potent,Non-Toxic Antimicrobial Agents Based upon the Structure ofthe Frog Skin Peptide,Temporin-1CEb from ChineseBrown Frog,Rana chensinensis[J]. Chemical Biology&Drug Design,2012,79(5):653-662.
[17]袁海恋,施溯筠.响应面法优化林蛙皮中透明质酸的提取工艺[J].食品工业科技,2016,37(8):196-200.
[18]张晶,胡春霞,王战勇,等.林蛙卵油的提取研究[J].氨基酸和生物资源,2008,30(1):10-12.
[19]金莉莉,王秋雨,娄虹,等.林蛙卵油脂肪酸组分的分析研究[J].食品科学,2004,25(10):232-234.
[20]赵超,叶海青,侯萍萍,等.微波辅助提取林蛙卵油的工艺优化及脂肪酸组成分析[J].食品科学,2017,38(22):263-268.
[21]张肃,胡春晓,金莉莉,等.东北林蛙卵蛋白抗疲劳活性研究[J].特产研究,2010,32(1):7-9.
[22]李永政,胡春晓,王铮,等.东北林蛙卵蛋白酶解工艺及其酶解物的抗疲劳活性[J].食品科学,2012(9):235-239.
[23] Shen Y,Liu Y,Ma J,et al.Immunoreactivity of c-kit re-ceptor protein during the prehibernation period in the o-viduct of the Chinese brown frog,Rana chensinensis[J].Journal of Veterinary Medical Science,2012,74(2):209.
[24]薛冰,金在久,施溯筠.林蛙皮的抗氧化性研究[J].华西药学杂志,2010,25(4):431-433.
[25]苏玉春,陈光,郭会楠,等.林蛙卵黑色素的提取工艺及其抗氧化活性[J].西北农林科技大学学报(自然科学版),2017,45(2):196-202.
[26] Wang Z,Zhao Y,Su T,et al.Characterization and an-tioxidant activity in vitro and in vivo of polysaccharidepurified fromRana chensinensis,skin[J]. CarbohydrPolym,2015(126):17-22.
[27] Che W,Yang Z,Song L,et al.Anticancer mechanismsof temporin-1CEa,an amphipathic helical antimicrobialpeptide,in Bcap-37 human breast cancer cells[J]. LifeSciences,2013,92(20-21):1004-1014.
[28] Wang C,Tian L L,Li S,et al.Rapid Cytotoxicity of An-timicrobial Peptide Tempoprin-1CEa in Breast CancerCells through Membrane Destruction and IntracellularCalcium Mechanism[J].Plos One,2013,8(4):e60462.
[29]巢警殳,杜鹃,刘雅娟.林蛙皮活性肽对小鼠免疫功能影响的试验研究[J].安徽农业科学,2012,40(21):10894-10895.
[30]李俊峰.中国林蛙资源的综合利用和开发[J].安徽农学通报,2009,15(3):159-160.
[31]张鑫,李思明,邓晨,等.林蛙皮多肽对Ha Ca T细胞增殖及凋亡的影响[J].中国兽医学报,2014,34(6):946-950.
[32] Mei Z,Li X,Li S,et al. Electrospun poly(l-lactide)/zein nanofiber mats loaded with Rana chensinensis,skin peptides for wound dressing[J]. Journal ofMaterials Science Materials in Medicine,2016,27(9):136.
[33]彭飞,徐峰,赵倩,等.中国林蛙卵油的抗惊厥作用及其与单胺神经递质的关系[J].中国药学杂志,2005,39(12):912-915.
[34]苑春莉,孙连坤,康劲松.林蛙卵油灌胃对于雄激素预处理大鼠妇科内分泌的影响[J].中国实验诊断学,2010,14(2):196-198.
[35]尹云厚,陈宁宁,常雷,等.东北林蛙(Ranadybowskii)卵油脂肪酸体外抗氧化性和保湿性研究[J].经济动物学报,2018(1):30-36+35.
[36]沈雪,杨秀东,张艳,等.林蛙油口服液在D-半乳糖诱导氧化损伤模型小鼠体内的抗氧化作用[J].吉林化工学院学报,2016,33(7):17-20.
[37]赵丹玉,侯长余,王艳杰,等.林蛙卵核糖核酸酶的抗肿瘤作用及对淋巴细胞转化的影响[J].中国生化药物杂志,2010,31(4):228-230.
[38]吴世玉,孟祥敏,刘俊梅,等.林蛙卵黑色素的理化性质及其抗氧化活性研究[J].食品研究与开发,2018(14):25-29.
[2]沈雪,崔浩,杨秀东,等.林蛙油水溶性蛋白质的制备与相对分子量测定[J].吉林化工学院学报,2016,33(9):11-14.
[3] Zhang Y,Liu Y,Zhu K,et al.Acute Toxicity,Antioxi-dant,and Antifatigue Activities of Protein-Rich Extractfrom Oviductus ranae[J].Oxidative Medicine and Cel-lular Longevity,2018(21):1-14.
[4]郑淼,周亚丹,赵敏.东北林蛙皮中胶原蛋白含量的测定及提取工艺[J].东北林业大学学报,2008,36(7):81-83.
[5]吕玲玲,金香淑,施溯筠.林蛙皮胶原蛋白的提取及抗氧化性[J].食品研究与开发,2013(10):20-22.
[6]李永政,胡春晓,王铮,等.东北林蛙卵蛋白酶解工艺及其酶解物的抗疲劳活性[J].食品科学,2012,33(9):235-239.
[7]季晓枫,林凤,邱芳萍.响应面法优化水酶法提取林蛙卵蛋白[J].长春工业大学学报(自然科学版),2013,34(2):137-144.
[8]陶凤云,赵伟,林强,等.中国林蛙卵核糖核酸酶的分离纯化及其抗肿瘤作用[J].中国生物工程杂志,2010,30(5):103-109.
[9] Wang Z,Zhao Y,Su T. Extraction and antioxidantactivity of polysaccharides fromRana chensinensis skin[J].Carbohydr Polym,2015,115(115):25-31.
[10]赵玉红,赵小旭,姜晓青.超声波-双酶法协同提取林蛙皮多糖的工艺优化[J].食品工业科技,2012,33(11):230-234.
[11]陈大勇,杨靖,李硕,等.林蛙卵多糖的提取工艺及其抗氧化作用研究[J].西北农林科技大学学报(自然科学版),2013(12):149-154.
[12]侯召华,金春爱,孙晓东,等.蛙类皮肤生物活性肽的研究进展[J].食品科技,2013(5):260-264.
[13] Zhang X,Cheng Y,Yang Y,et al.Polypeptides from theSkin ofRana Chensinensis Exert the Antioxidant andAntiapoptotic Activities on Ha Ca T cells[J].Animal Bi-otechnology,2017,28(1):1-10.
[14]杨闯,王俊玲,张传军,等.林蛙皮生物活性肽3种提取方法的比较研究[J].黑龙江畜牧兽医,2015(5):174-235.
[15] Shang D,Wang C,Wei S,et al. Membrane interactionand antibacterial properties of chensinin-1,an antimi-crobial peptide with atypical structural features fromthe skin ofRana chensinensis[J]. Appl. Microbiol. Bio-technol,2012,96(6):1551-1560.
[16] Shang D,Li X,Sun Y,et al. Design of Potent,Non-Toxic Antimicrobial Agents Based upon the Structure ofthe Frog Skin Peptide,Temporin-1CEb from ChineseBrown Frog,Rana chensinensis[J]. Chemical Biology&Drug Design,2012,79(5):653-662.
[17]袁海恋,施溯筠.响应面法优化林蛙皮中透明质酸的提取工艺[J].食品工业科技,2016,37(8):196-200.
[18]张晶,胡春霞,王战勇,等.林蛙卵油的提取研究[J].氨基酸和生物资源,2008,30(1):10-12.
[19]金莉莉,王秋雨,娄虹,等.林蛙卵油脂肪酸组分的分析研究[J].食品科学,2004,25(10):232-234.
[20]赵超,叶海青,侯萍萍,等.微波辅助提取林蛙卵油的工艺优化及脂肪酸组成分析[J].食品科学,2017,38(22):263-268.
[21]张肃,胡春晓,金莉莉,等.东北林蛙卵蛋白抗疲劳活性研究[J].特产研究,2010,32(1):7-9.
[22]李永政,胡春晓,王铮,等.东北林蛙卵蛋白酶解工艺及其酶解物的抗疲劳活性[J].食品科学,2012(9):235-239.
[23] Shen Y,Liu Y,Ma J,et al.Immunoreactivity of c-kit re-ceptor protein during the prehibernation period in the o-viduct of the Chinese brown frog,Rana chensinensis[J].Journal of Veterinary Medical Science,2012,74(2):209.
[24]薛冰,金在久,施溯筠.林蛙皮的抗氧化性研究[J].华西药学杂志,2010,25(4):431-433.
[25]苏玉春,陈光,郭会楠,等.林蛙卵黑色素的提取工艺及其抗氧化活性[J].西北农林科技大学学报(自然科学版),2017,45(2):196-202.
[26] Wang Z,Zhao Y,Su T,et al.Characterization and an-tioxidant activity in vitro and in vivo of polysaccharidepurified fromRana chensinensis,skin[J]. CarbohydrPolym,2015(126):17-22.
[27] Che W,Yang Z,Song L,et al.Anticancer mechanismsof temporin-1CEa,an amphipathic helical antimicrobialpeptide,in Bcap-37 human breast cancer cells[J]. LifeSciences,2013,92(20-21):1004-1014.
[28] Wang C,Tian L L,Li S,et al.Rapid Cytotoxicity of An-timicrobial Peptide Tempoprin-1CEa in Breast CancerCells through Membrane Destruction and IntracellularCalcium Mechanism[J].Plos One,2013,8(4):e60462.
[29]巢警殳,杜鹃,刘雅娟.林蛙皮活性肽对小鼠免疫功能影响的试验研究[J].安徽农业科学,2012,40(21):10894-10895.
[30]李俊峰.中国林蛙资源的综合利用和开发[J].安徽农学通报,2009,15(3):159-160.
[31]张鑫,李思明,邓晨,等.林蛙皮多肽对Ha Ca T细胞增殖及凋亡的影响[J].中国兽医学报,2014,34(6):946-950.
[32] Mei Z,Li X,Li S,et al. Electrospun poly(l-lactide)/zein nanofiber mats loaded with Rana chensinensis,skin peptides for wound dressing[J]. Journal ofMaterials Science Materials in Medicine,2016,27(9):136.
[33]彭飞,徐峰,赵倩,等.中国林蛙卵油的抗惊厥作用及其与单胺神经递质的关系[J].中国药学杂志,2005,39(12):912-915.
[34]苑春莉,孙连坤,康劲松.林蛙卵油灌胃对于雄激素预处理大鼠妇科内分泌的影响[J].中国实验诊断学,2010,14(2):196-198.
[35]尹云厚,陈宁宁,常雷,等.东北林蛙(Ranadybowskii)卵油脂肪酸体外抗氧化性和保湿性研究[J].经济动物学报,2018(1):30-36+35.
[36]沈雪,杨秀东,张艳,等.林蛙油口服液在D-半乳糖诱导氧化损伤模型小鼠体内的抗氧化作用[J].吉林化工学院学报,2016,33(7):17-20.
[37]赵丹玉,侯长余,王艳杰,等.林蛙卵核糖核酸酶的抗肿瘤作用及对淋巴细胞转化的影响[J].中国生化药物杂志,2010,31(4):228-230.
[38]吴世玉,孟祥敏,刘俊梅,等.林蛙卵黑色素的理化性质及其抗氧化活性研究[J].食品研究与开发,2018(14):25-29.