中药止血方对尿道前列腺电切术后出血临床疗效观察
|
摘要
目的:探讨中药止血方口服汤剂对经尿道前列腺电切术(TURP)后出血的治疗效果。方法:2015年1月—2017年6月行经尿道前列腺电切术的良性前列腺增生症患者75例,其中中药止血方治疗组37例,对照组38例。对照组常规预防感染、对症治疗,中药止血方治疗组口服中药止血方,两组患者术后均不用其他止血药物。术后对"即刻、第1天、第3天、第7天"4个时段尿管引流液颜色和尿隐血进行记录并比较。将尿管引流颜色分为"鲜红、淡红、清亮/淡黄"3个标准,尿常规隐血(BLU)分为"-、1+、2+、3+"4个标准,血红蛋白下降幅度分为10 g/L以下、10～30 g/L、30 g/L以上。结果:两组患者术后即刻、术后第1天、术后第3天尿管引流液颜色比较无明显差异(P>0.05);术后第7天尿管颜色比较有显著性差异(P<0.05)。尿常规隐血术后即刻、术后第1天比较无明显差异(P>0.05);术后第3天和第7天比较有显著差异(P<0.05);血红蛋白下降幅度术后即刻、术后第1天比较无明显差异(P>0.05);术后第3天和第7天比较有显著差异(P<0.05)。结论:中药止血方口服汤剂减少经尿道前列腺电切术后创面出血,疗效显著,值得临床推广应用。
Objective:To investigate the curative effect of Traditional Chinese Medicine ZhixueDecoction on hemorrhage after transurethral resection of prostate(TURP). Methods:From January 2015 to June 2017,75 cases of benign prostatic hyperplasia(BPH)treated by transurethral resection of prostate were included. Among them,37 cases were treated with traditional Chinese medicine for the treatment of hemostasis and 38 cases were as control. The control group was given routinely prevent infection,symptomatic treatment,the treatment group was given Traditional Chinese Medicine ZhixueDecoction stop bleeding,two groups of patients didn't given other hemostatic drugs after operation.Postoperative urinary exudate color and urinary occult blood were recorded and compared at four time points of"immediately,the 1 st day,the 3 rd day and the 7 th day after operation". The standard of urinary drainage was divided into three standards:bright red,light red,clear/light yellow. Urinary routine occult blood(BLU)was divided into four criteria of"-,1+,2+,3+"and hemoglobin decline was divided into 10 g/L or less,10-30 g/L,and 30 g/L or more. Results:There was no significant difference in the color of catheter between the two groups immediately and 1 st day,3 rd day after operation(P>0.05),but on the 7 th day after operation was significantly different(P<0.05). There was no significant difference in the BLU between the two groups immediately and 1 st day after operation(P>0.05),but on the 3 rd day and the 7 th day after operation was significantly different(P<0.05). The decrease of hemoglobin immediately and 1 st day after operation was no significant difference(P>0.05),but the 3 rd day and the 7 th day after operation was significantly different(P<0.05).Conclusion:Traditional Chinese Medicine Zhixue Decoction can reduce wound bleeding after TURP and the curative effect is significant. It is worthy of clinical application.
Objective:To investigate the curative effect of Traditional Chinese Medicine ZhixueDecoction on hemorrhage after transurethral resection of prostate(TURP). Methods:From January 2015 to June 2017,75 cases of benign prostatic hyperplasia(BPH)treated by transurethral resection of prostate were included. Among them,37 cases were treated with traditional Chinese medicine for the treatment of hemostasis and 38 cases were as control. The control group was given routinely prevent infection,symptomatic treatment,the treatment group was given Traditional Chinese Medicine ZhixueDecoction stop bleeding,two groups of patients didn't given other hemostatic drugs after operation.Postoperative urinary exudate color and urinary occult blood were recorded and compared at four time points of"immediately,the 1 st day,the 3 rd day and the 7 th day after operation". The standard of urinary drainage was divided into three standards:bright red,light red,clear/light yellow. Urinary routine occult blood(BLU)was divided into four criteria of"-,1+,2+,3+"and hemoglobin decline was divided into 10 g/L or less,10-30 g/L,and 30 g/L or more. Results:There was no significant difference in the color of catheter between the two groups immediately and 1 st day,3 rd day after operation(P>0.05),but on the 7 th day after operation was significantly different(P<0.05). There was no significant difference in the BLU between the two groups immediately and 1 st day after operation(P>0.05),but on the 3 rd day and the 7 th day after operation was significantly different(P<0.05). The decrease of hemoglobin immediately and 1 st day after operation was no significant difference(P>0.05),but the 3 rd day and the 7 th day after operation was significantly different(P<0.05).Conclusion:Traditional Chinese Medicine Zhixue Decoction can reduce wound bleeding after TURP and the curative effect is significant. It is worthy of clinical application.
引文
[1]朱子健.第六次全国人口普查主要数据发布[J].中学政史地:初中适用,2011(7):55-58.
[2]宋全成,崔瑞宁.人口高速老龄化的理论应对——从健康老龄化到积极老龄化[J].山东社会科学,2013,212(4):36-41.
[3]Yancik R,Ershler W,Satariano W,et al. Report of the national institute on aging task force on comorbidity[J]. J Gerontol A Biol Sci Med Sci,2007,62(3):275-280.
[4]刘俊含,闫论,施红,等.老年群体共存疾病的现况调查[J].保健医学研究与实践,2017,14(6):39-42.
[5]于晓华,梁国庆,吴旻,等.上海、浙江两地男性良性前列腺增生患病率调查[J].中国男科学杂志,2015,29(1):35-38.
[6]曾明祥.经尿道电切术治疗前列腺增生症的临床疗效观察[J].当代医学,2013,19(1):102-103.
[7]Agarwal A,Eryuzlu LN,Cartwright R,et al. What is the most bothersome lower urinary tract symptom Individual and population-level perspectives for both men and women[J]. Eur Urol,2014,65(6):1211-1217.
[8]Mangera A,Chapple C. An evidence based update on the investigation and management of male lower urinary tract symptoms[J]. Urologiia,2015(2):94-102.
[9]孙自学,宋春生,邢俊平,等.良性前列腺增生中西医结合诊疗指南(试行版)[J].中华男科学杂志,2017,23(3):280-285.
[10]马秀芬,韩清玲,李鑫,等.经尿道前列腺电切术对老年前列腺增生患者生活质量的影响[J].中国老年学杂志,2014(8):2283-2284.
[11]刘和谦,陈弋生,邹滨,等.经尿道前列腺电切术严重并发症的临床分析[J].中华泌尿外科杂志,2016,37(7):515-518.
[12]那彦群.中国泌尿外科疾病诊断治疗指南手册[M].北京:人民卫生出版社,2014.
[13]南京中医药大学.煎药与服药[M].北京:人民卫生电子音像出版社,2005.
[14]范伟洪,郑少波.前列腺汽化电切术后出血的原因及治疗方法分析[J].河南外科学杂志,2017,23(5):105-106.
[15]董高志,黄献宏,林盛强.经尿道等离子电切术对老年前列腺增生患者临床症状、生活质量及术后并发症的影响[J].大家健康(上旬版),2017,11(12):126-127.
[16]田生平.经尿道前列腺电切术与经尿道前列腺剜除术治疗前列腺增生症的疗效对比分析[J].中国临床医生杂志,2017,45(12):76-79.
[17]杨学来,高海鹏,李天庆,等.县、乡级医疗机构医疗设备现状分析[J].中国医疗设备,2018,33(1):174-178.
[18]陈迪才.经尿道前列腺电切术后出血的原因及治疗研究[J].临床泌尿外科杂志,2008,23(5):372-373,376
[19]张文军.药物的不良反应(二十六)[J].开卷有益(求医问药),2005(10):40.
[20]李强,王劲翔.经尿道前列腺气化电切术联合中药治疗前列腺增生108例[J].新疆中医药药,2011,29(5):12-13
[21]钱春雷.清热凉血类中药治疗前列腺电切术后出血的临床观察[J].中国继续医学教育,2017,9(36):109-111.
[22]王祠菊,陈喜建,周素芳,等.吴文尧教授治疗血淋经验介绍[J].贵阳中医学院学报,2017(5):16-18.
[23]吕选民,姬水英.第十四讲白茅根[J].中国乡村医药,2016(15):51-52.
[24]陈菊.藕节功能性成分的提取分离及产品开发[D].无锡:江南大学,2009.
[25]李景辉,陈才法,李雯雯.蒲黄药理活性及临床应用[J].安徽农业科学,2011,39(16):9604-9606.
[26]祁爱蓉,徐彩,蔡芬芳,等.小蓟、小蓟炭的主要成分及止血作用研究综述[J].内蒙古中医药,2012,31(20):96-99.
[27]周梦颖,钟琛聪.地榆活性成分及药理作用研究进展[J].现代养生,2018(2):89-90.
[28]杜国成.中药鞣质成分的药理作用探析[J].中国医药科学,2011,1(16):27-33.
[29]张向阳,赵如同,刘春燕,等.地榆、地榆炭对小鼠止血作用影响的实验研究[J].河北中医,2017,39(5):735-738.
[30]盛彬.中草药三七的药理作用及临床研究[J].心理医生,2017,23(30):94-95.
[31]孙凤志,孙明江,吕旭潇.中药三七止血活血作用的研究进展[J].医学研究杂志,2013,42(9):24-26.
[32]刘荣华,付丽娜,陈兰英,等.白茅根化学成分与药理研究进展[J].江西中医学院学报,2010,22(4):80-83.
[2]宋全成,崔瑞宁.人口高速老龄化的理论应对——从健康老龄化到积极老龄化[J].山东社会科学,2013,212(4):36-41.
[3]Yancik R,Ershler W,Satariano W,et al. Report of the national institute on aging task force on comorbidity[J]. J Gerontol A Biol Sci Med Sci,2007,62(3):275-280.
[4]刘俊含,闫论,施红,等.老年群体共存疾病的现况调查[J].保健医学研究与实践,2017,14(6):39-42.
[5]于晓华,梁国庆,吴旻,等.上海、浙江两地男性良性前列腺增生患病率调查[J].中国男科学杂志,2015,29(1):35-38.
[6]曾明祥.经尿道电切术治疗前列腺增生症的临床疗效观察[J].当代医学,2013,19(1):102-103.
[7]Agarwal A,Eryuzlu LN,Cartwright R,et al. What is the most bothersome lower urinary tract symptom Individual and population-level perspectives for both men and women[J]. Eur Urol,2014,65(6):1211-1217.
[8]Mangera A,Chapple C. An evidence based update on the investigation and management of male lower urinary tract symptoms[J]. Urologiia,2015(2):94-102.
[9]孙自学,宋春生,邢俊平,等.良性前列腺增生中西医结合诊疗指南(试行版)[J].中华男科学杂志,2017,23(3):280-285.
[10]马秀芬,韩清玲,李鑫,等.经尿道前列腺电切术对老年前列腺增生患者生活质量的影响[J].中国老年学杂志,2014(8):2283-2284.
[11]刘和谦,陈弋生,邹滨,等.经尿道前列腺电切术严重并发症的临床分析[J].中华泌尿外科杂志,2016,37(7):515-518.
[12]那彦群.中国泌尿外科疾病诊断治疗指南手册[M].北京:人民卫生出版社,2014.
[13]南京中医药大学.煎药与服药[M].北京:人民卫生电子音像出版社,2005.
[14]范伟洪,郑少波.前列腺汽化电切术后出血的原因及治疗方法分析[J].河南外科学杂志,2017,23(5):105-106.
[15]董高志,黄献宏,林盛强.经尿道等离子电切术对老年前列腺增生患者临床症状、生活质量及术后并发症的影响[J].大家健康(上旬版),2017,11(12):126-127.
[16]田生平.经尿道前列腺电切术与经尿道前列腺剜除术治疗前列腺增生症的疗效对比分析[J].中国临床医生杂志,2017,45(12):76-79.
[17]杨学来,高海鹏,李天庆,等.县、乡级医疗机构医疗设备现状分析[J].中国医疗设备,2018,33(1):174-178.
[18]陈迪才.经尿道前列腺电切术后出血的原因及治疗研究[J].临床泌尿外科杂志,2008,23(5):372-373,376
[19]张文军.药物的不良反应(二十六)[J].开卷有益(求医问药),2005(10):40.
[20]李强,王劲翔.经尿道前列腺气化电切术联合中药治疗前列腺增生108例[J].新疆中医药药,2011,29(5):12-13
[21]钱春雷.清热凉血类中药治疗前列腺电切术后出血的临床观察[J].中国继续医学教育,2017,9(36):109-111.
[22]王祠菊,陈喜建,周素芳,等.吴文尧教授治疗血淋经验介绍[J].贵阳中医学院学报,2017(5):16-18.
[23]吕选民,姬水英.第十四讲白茅根[J].中国乡村医药,2016(15):51-52.
[24]陈菊.藕节功能性成分的提取分离及产品开发[D].无锡:江南大学,2009.
[25]李景辉,陈才法,李雯雯.蒲黄药理活性及临床应用[J].安徽农业科学,2011,39(16):9604-9606.
[26]祁爱蓉,徐彩,蔡芬芳,等.小蓟、小蓟炭的主要成分及止血作用研究综述[J].内蒙古中医药,2012,31(20):96-99.
[27]周梦颖,钟琛聪.地榆活性成分及药理作用研究进展[J].现代养生,2018(2):89-90.
[28]杜国成.中药鞣质成分的药理作用探析[J].中国医药科学,2011,1(16):27-33.
[29]张向阳,赵如同,刘春燕,等.地榆、地榆炭对小鼠止血作用影响的实验研究[J].河北中医,2017,39(5):735-738.
[30]盛彬.中草药三七的药理作用及临床研究[J].心理医生,2017,23(30):94-95.
[31]孙凤志,孙明江,吕旭潇.中药三七止血活血作用的研究进展[J].医学研究杂志,2013,42(9):24-26.
[32]刘荣华,付丽娜,陈兰英,等.白茅根化学成分与药理研究进展[J].江西中医学院学报,2010,22(4):80-83.