2014年天津市恶性肿瘤流行情况及疾病负担分析
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摘要
[目的]分析2014年天津市恶性肿瘤发病、死亡情况及疾病负担。[方法]分析2014年天津市户籍居民的肿瘤登记随访数据,计算发病率、死亡率、构成比、中国人口标化率、世界人口标化率,并分析恶性肿瘤造成的疾病负担。[结果] 2014年,天津市恶性肿瘤发病率为306.71/10万(男性303.28/10万,女性310.17/10万),中标率179.52/10万。恶性肿瘤发病率前5位为肺癌、女性乳腺癌、甲状腺癌、结直肠癌和肝癌。全市恶性肿瘤死亡率为180.78/10万(男性210.79/10万,女性150.58/10万),中标率93.08/10万。恶性肿瘤死亡率前5位为肺癌、肝癌、结直肠癌、胃癌和女性乳腺癌。恶性肿瘤所致伤残调整寿命年(disability adjusted life year,DALY)率为23.3/千人,男性和女性分别为26.1/千人和20.5/千人。[结论]天津市应针对肺癌、结直肠癌、肝癌、胃癌、女性乳腺癌等癌种开展重点防治,在全面掌握癌症流行情况的基础上,完善癌症综合防治网络,降低癌症疾病负担。
[Purpose] To analyze the incidence,mortality and disease burden of cancer in Tianjin,2014. [Methods] Stratified by areas,gender and age groups,the incidence,mortality,age-standardized rates(ASR) by Chinese standard population and world population,constituent ratio and disability-adjusted life year(DALY) of cancer in Tianjin were calculated. [Results] In 2014,the cancer incidence rate in Tianjin was 306.71/10~5(303.28/10~5 for males,310.17/10~5 for females),and the ASR China and ASR world were 179.52/10~5 and 172.87/10~5,respectively. Cancers of lung,female breast,thyroid gland,colorectum and liver were the most common cancers. The cancer mortality rate was 180.78/10~5(210.79/10~5 for males,150.58/10~5 for females),and the ASR China and ASR world were 93.08/10~5 and 91.43/10~5,respectively. Lung cancer,liver cancer,colorectal cancer,stomach cancer and female breast cancer were the most fatal cancers. The DALYs caused by cancer was 23.3 healthy life years per 1000 person years,and 26.1 and 20.5 healthy life years per 1000 person years in males and in females,respectively. [Conclusion] Cancers of lung,colorectum,liver,stomach and female breast are the major healthy threats in Tianjin. To decrease the disease burden of cancer,comprehensive efforts of cancer prevention and control should be carried out in Tianjin persistently.
[Purpose] To analyze the incidence,mortality and disease burden of cancer in Tianjin,2014. [Methods] Stratified by areas,gender and age groups,the incidence,mortality,age-standardized rates(ASR) by Chinese standard population and world population,constituent ratio and disability-adjusted life year(DALY) of cancer in Tianjin were calculated. [Results] In 2014,the cancer incidence rate in Tianjin was 306.71/10~5(303.28/10~5 for males,310.17/10~5 for females),and the ASR China and ASR world were 179.52/10~5 and 172.87/10~5,respectively. Cancers of lung,female breast,thyroid gland,colorectum and liver were the most common cancers. The cancer mortality rate was 180.78/10~5(210.79/10~5 for males,150.58/10~5 for females),and the ASR China and ASR world were 93.08/10~5 and 91.43/10~5,respectively. Lung cancer,liver cancer,colorectal cancer,stomach cancer and female breast cancer were the most fatal cancers. The DALYs caused by cancer was 23.3 healthy life years per 1000 person years,and 26.1 and 20.5 healthy life years per 1000 person years in males and in females,respectively. [Conclusion] Cancers of lung,colorectum,liver,stomach and female breast are the major healthy threats in Tianjin. To decrease the disease burden of cancer,comprehensive efforts of cancer prevention and control should be carried out in Tianjin persistently.
引文
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[26]Lee IM,Shiroma EJ,Lobelo F,et al.Effect of physical inactivity on major non-communicable diseases worldwide:an analysis of burden of disease and life expectancy[J].Lancet,2012,380(9838):219-229.
[27]Inoue M,Sawada N,Matsuda T,et al.Attributable causes of cancer in Japan in 2005-systematic assessment to estimate current burden of cancer attributable to known preventable risk factors in Japan[J].Ann Oncol,2012,23(5):1362-1369.
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[29]Xu T,Li W,Hu B,et al.Survey of smoking and passive smoking status among Chinese adults in 11 provinces[J].Chinese Journal of Prevention and Control of Chronic Non-Communication Diseases,2010,3:229-230.[徐涛,李卫,胡泊,等.中国11省市成年人吸烟和被动吸烟情况调查[J].中国慢性病预防与控制,2010,3:229-230.]
[30]Cao CC,Hu RY,Li JT,et al.Survey on smoking rate and quitting intention among urban adults in Hangzhou[J].Chinese Journal of Preventive Medicine,2016,5:331-335.[曹承建,何晓燕,李金涛.杭州城市成人吸烟率及吸烟者戒烟状况分析[J].中国预防医学杂志,2016,5:331-335.]
[31]Social Surveys Section,Census and Statistics Department,Hong Kong Special Administrative Region.Thematic household survey report No.59[R].Hongkong:Census and Statistics Department,Hong Kong Special Administrative Region,2016.[香港特别行政区政府统计处社会统计调查组.主题性住户统计调查第59号报告书[R].香港:香港特别行政区政府统计处,2016.]
[32]Marley A R,Nan H.Epidemiology of colorectal cancer[J].Int J Mol Epidemiol Genet,2016,7(3):105-114.
[33]Gong WW,Hu RY,Luo SL,et al.Analysis on incidence and mortality characteristics of thyroid cancer during 2007to 2011 in Zhejiang province[J].Zhejiang Journal of Preventive Medicine,2014,5:433-437.[龚巍巍,胡如英,罗胜兰,等.浙江省2007-2011年甲状腺癌发病及死亡特征分析[J].浙江预防医学,2014,5:433-437.]
[34]Zhou F,Wu CX,Zheng Y,et al.Temporal trend of thyroid cancer incidence in urban Shanghai,1981-2010[J].Journal of Environmental Occupational Medicine,2015,11:997-1002.[周峰,吴春晓,郑莹,等.1981-2010年上海市市区甲状腺癌的发病趋势[J].环境与职业医学,2015,11:997-1002.]
[35]Derwahl M,Nicula D.Estrogen and its role in thyroid cancer[J].Endocr Relat Cancer,2014,21(5):T273-T283.
[2]The National Central Cancer Registry.Guideline for Chinese cancer registration[M].Beijing:Peking Union Medical College Press,2004.48-50.[全国肿瘤登记中心.中国肿瘤登记工作指导手册[M].北京:中国协和医科大学出版社,2004.48-50.]
[3]Parkin DM,Chen VW,Ferlay J,et al.Comparability and quality control in cancer registration.IARC Technica Report No.19[M].Lyon:IARC,1994.
[4]Curado MP,Edwards B,Shin HR,et al.Cancer incidence in five continents,Vol.Ⅺ[M].Lyon:IARC,2008.
[5]Devleesschauwer B,Havelaar AH,Maertens DNC,et al.DALY calculation in practice:a stepwise approach[J].Int J Public Health,2014,59(3):571-574.
[6]Ma JX,Sun JD,Fu ZT,et al.Estimation of disability weights on malignant neoplasms in Shandong province[J].Chinese Journal of Epidemiology,2008,29(12):1208-1212.[马吉祥,孙建东,付振涛,等.山东省恶性肿瘤残疾权重的测量[J].中华流行病学杂志,2008,29(12):1208-1212.]
[7]World Health Organization.Health statistics and information systems[EB/OL].http://www.who.int/healthinfo/global_burden_disease/tools_national/en/,2018-07-23.
[8]Shen CF,Wang DZ,Zhang S,et al.Cancer incidence in Tianjin,2010~2012[J].China Cancer,2017,26(1):18-24.[沈成凤,王德征,张爽,等.2010~2012年天津市恶性肿瘤发病分析[J].中国肿瘤,2017,26(1):18-24.]
[9]Shi J,Liang D,Li DJ,et al.Report of incidence and mortality of malignant tumor in Hebei province,2014[J].Tumor,2018,38(4):329-338.[师金,梁迪,李道娟,等.河北省2014年恶性肿瘤发病与死亡情况分析[J].肿瘤,2018(4):329-338.]
[10]Han RQ,Wu M,Luo PF,et al.Cancer incidence and mortality in Jiangsu Province,2014[J].Journal of Cancer Control and Treatment,2018,31(1):24-31.[韩仁强,武鸣,罗鹏飞,等.2014年江苏省恶性肿瘤发病和死亡分析[J].肿瘤预防与治疗,2018,31(1):24-31.]
[11]Yu JH,Li QL,Rong MH,et al.Cancer incidence and mortality in cancer registries in Guangxi,2013[J].Chinese Journal of Oncology Prevention and Treat meat,2017,1:30-39.[余家华,李秋林,容敏华,等.2013年广西肿瘤登记地区恶性肿瘤发病和死亡分析[J].中国癌症防治杂志,2017,1:30-39.]
[12]Chen WQ,Sun KX,Zheng RS,et al.Report of cancer incidence and mortality in different areas of China,2014[J].China Cancer,2018,27(1):1-14.[陈万青,孙可欣,郑荣寿,等.2014年中国分地区恶性肿瘤发病和死亡分析[J].中国肿瘤,2018,27(1):1-14.]
[13]Hong HY.The impact and measures of aging on the transformation and upgrading of Tianjin economic[J].E-conomic Out Look the Bohai Sea,2015,4:7-11.[洪海钰.人口老龄化对天津经济转型升级的影响及对策研究[J].环渤海经济瞭望,2015,4:7-11.]
[14]Wang QS,Chen WQ,Zheng RS,et al.Joinpoint linear regression analysis of cancer age-specific incidence rate and its significance for cancer control[J].China Cancer,2013,22(3):180-185.[王庆生,陈万青,郑荣寿,等.癌症年龄别发病率的Joinpoint线性回归分析及其在癌症防控中的意义[J].中国肿瘤,2013,22(3):180-185.]
[15]Chen WQ,Zheng RS,Zhang SW,et al.Report of cancer incidence and mortality in China,2013[J].China Cancer,2017,26(1):1-7.[陈万青,郑荣寿,张思维,等.2013年中国恶性肿瘤发病和死亡分析[J].中国肿瘤,2017,26(1):1-7.]
[16]Wang P,Xu C,Yu C.Age-period-cohort analysis on the cancer mortality in rural China:1990-2010[J].Int J Equity Health,2014,13:1.
[17]Thakkar JP,McCarthy BJ,Villano JL.Age-specific cancer incidence rates increase through the oldest age groups[J].Am J Med Sci,2014,348(1):65-70.
[18]Sun JD,Guo XL,Li WK,et al.Estimating the burden of malignant neoplasm in Shandong province[J].Chinese Health Economics,2007,26(8):64-66.[孙建东,郭晓雷,李维卡,等.山东省恶性肿瘤疾病负担研究[J].中国卫生经济,2007(08):64-66.]
[19]Hu WB,Zhang T,Qin W,et al.An Analysis of cancer mortality and burden of disease in Kunshan,Jiangsu province,2011[J].China Cancer,2015,11:905-909.[胡文斌,张婷,秦威,等.江苏省昆山市2011年恶性肿瘤死亡率与疾病负担分析[J].中国肿瘤,2015,11:905-909.]
[20]Wang XH,Liu J,Zhang C,et al.Burden of malignant neoplasm in Guiyang citizen[J].China Health Industry,2017,23:167-169.[王晓晖,刘靖,张超,等.贵阳市居民恶性肿瘤疾病负担分析[J].中国卫生产业,2017,23:167-169.]
[21]Pan BY,Liang BH,Du L,et al.Research on disease burden of malignant neoplasm in Guangzhou citizen[J].Journal of Tropical Medicine,2011,1:85-87.[潘冰莹,梁伯衡,杜琳,等.广州市居民恶性肿瘤疾病负担研究[J].热带医学杂志,2011,1:85-87.]
[22]Mao BH,Bai YN,Chen XZ,et al.Disease burden of common malignant neoplasms in Gansu province[J].Journal of Lanzhou University(Medical Science),2013,3:64-66.[毛宝宏,白亚娜,陈学忠,等.甘肃省主要恶性肿瘤疾病负担分析[J].兰州大学学报(医学版),2013,3:64-66.]
[23]Yang L,Chen NS,Huang KY,et al.Burden of cancer in Guangxi province 2008-2013[J].Chinese Journal Disease Control and Prevention,2016,5:500-503.[杨丽,陈娜萦,黄开勇,等.2008-2013年广西居民恶性肿瘤疾病负担的研究[J].中华疾病控制杂志,2016,5:500-503.]
[24]Institute for Health Metrics and Evaluation.Global health data exchange[EB/OL].http://ghdx.healthdata.org/gbd-results-tool,2018-07-23.
[25]Baade PD,Meng X,Sinclair C,et al.Estimating the future burden of cancers preventable by better diet and physical activity in Australia[J].Med J Aust,2012,196(5):337-340.
[26]Lee IM,Shiroma EJ,Lobelo F,et al.Effect of physical inactivity on major non-communicable diseases worldwide:an analysis of burden of disease and life expectancy[J].Lancet,2012,380(9838):219-229.
[27]Inoue M,Sawada N,Matsuda T,et al.Attributable causes of cancer in Japan in 2005-systematic assessment to estimate current burden of cancer attributable to known preventable risk factors in Japan[J].Ann Oncol,2012,23(5):1362-1369.
[28]Tianjin Center for Disease Control and Prevention.Health report for Tianjin residents,2016[R].Tianjin:Tianjin Center for Disease Control and Prevention,2017.[天津市疾病预防控制中心.天津市居民健康状况报告(2016年度)[R].天津:天津市疾病预防控制中心,2017.]
[29]Xu T,Li W,Hu B,et al.Survey of smoking and passive smoking status among Chinese adults in 11 provinces[J].Chinese Journal of Prevention and Control of Chronic Non-Communication Diseases,2010,3:229-230.[徐涛,李卫,胡泊,等.中国11省市成年人吸烟和被动吸烟情况调查[J].中国慢性病预防与控制,2010,3:229-230.]
[30]Cao CC,Hu RY,Li JT,et al.Survey on smoking rate and quitting intention among urban adults in Hangzhou[J].Chinese Journal of Preventive Medicine,2016,5:331-335.[曹承建,何晓燕,李金涛.杭州城市成人吸烟率及吸烟者戒烟状况分析[J].中国预防医学杂志,2016,5:331-335.]
[31]Social Surveys Section,Census and Statistics Department,Hong Kong Special Administrative Region.Thematic household survey report No.59[R].Hongkong:Census and Statistics Department,Hong Kong Special Administrative Region,2016.[香港特别行政区政府统计处社会统计调查组.主题性住户统计调查第59号报告书[R].香港:香港特别行政区政府统计处,2016.]
[32]Marley A R,Nan H.Epidemiology of colorectal cancer[J].Int J Mol Epidemiol Genet,2016,7(3):105-114.
[33]Gong WW,Hu RY,Luo SL,et al.Analysis on incidence and mortality characteristics of thyroid cancer during 2007to 2011 in Zhejiang province[J].Zhejiang Journal of Preventive Medicine,2014,5:433-437.[龚巍巍,胡如英,罗胜兰,等.浙江省2007-2011年甲状腺癌发病及死亡特征分析[J].浙江预防医学,2014,5:433-437.]
[34]Zhou F,Wu CX,Zheng Y,et al.Temporal trend of thyroid cancer incidence in urban Shanghai,1981-2010[J].Journal of Environmental Occupational Medicine,2015,11:997-1002.[周峰,吴春晓,郑莹,等.1981-2010年上海市市区甲状腺癌的发病趋势[J].环境与职业医学,2015,11:997-1002.]
[35]Derwahl M,Nicula D.Estrogen and its role in thyroid cancer[J].Endocr Relat Cancer,2014,21(5):T273-T283.