脑型Wilson病患者智力水平及智力结构的研究
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  • 英文篇名:Study on intelligence level and intelligence structure in brain type patients with Wilson's disease
  • 作者:李波 ; 王共强 ; 韩咏竹 ; 韩永升 ; 马心峰
  • 英文作者:Li Bo;Wang Gongqiang;Han Yongzhu;The Affiliated Hospital of Institute of Neurology of Anhui University of TCM;
  • 关键词:Wilson病 ; 肝豆状核变性 ; 晶体智力 ; 流体智力 ; 相关因素
  • 英文关键词:Wilson's disease;;Hepatolenticular degeneration;;Crystallized intelligence;;Fluid intelligence;;Related factors
  • 中文刊名:AHYX
  • 英文刊名:Anhui Medical Journal
  • 机构:安徽中医药大学神经病学研究所附属医院;
  • 出版日期:2014-04-30
  • 出版单位:安徽医学
  • 年:2014
  • 期:v.35
  • 基金:安徽省卫生厅科研基金项目(2012zy65)
  • 语种:中文;
  • 页:AHYX201404004
  • 页数:3
  • CN:04
  • ISSN:34-1077/R
  • 分类号:14-16
摘要
目的通过神经心理学测验评估脑型Wilson病(Wilson's disease,WD)患者晶体智力和流体智力水平,探讨其智力结构变化的特点及相关因素。方法选取32例脑型WD患者为研究对象,采用韦氏智力量表、瑞文标准推理测验(R'SPM)进行晶体智力和流体智力测评,运用SPSS 11.5软件分析患者的晶体智力、流体智力变化及相关因素。结果 43.75%脑型WD患者晶体智力水平下降,78.13%脑型WD患者流体智力水平下降,瑞文标准推理测验智商(RWIQ)得分低于韦氏智力测定全量表智商(FIQ)得分(P<0.05);韦氏智力测定言语量表智商(VIQ)、韦氏智力测定操作量表智商(PIQ)与FIQ呈正相关(P<0.05),瑞文标准推理测验E分测验(RWE)、性别与RWIQ呈正相关(P<0.05),FIQ与RWIQ无相关性(P>0.05)。结论脑型WD患者的智力结构存在不均衡受损,流体智力水平下降较晶体智力水平更为明显。流体智力和晶体智力不可相互替代。
        Objective Through conducting neuropsychological test to evaluate crystallized intelligence and fluid intelligence of brain type patients with Wilson's disease( WD),to analyze the characteristics of intelligence structure changing and other related factors. Methods Wechsler intelligence test and Raven's standard progressive matrices( R'SPM) were conducted among 32 brain type WD patients,in order to assess crystallized intelligence and fluid intelligence. The diversities of patients crystallized intelligence,fluid intelligence and other related factors were analysed by using SPSS 11. 5 software. Results 43. 75% brain type WD patients showed a decrease in crystallized intelligence while 78. 13% patients showed fluid intelligence drop. Moreover,Raven's standard progressive matrices intelligence quotient( RWIQ) ranking was significantly less than full measuring scale intelligence quotient( FIQ)( P < 0. 05),verbal intelligence quotient( VIQ) and performance intelligence quotient( PIQ) appeared significantly positive correlation( P < 0. 05) with FIQ. In addition,RWE,gender showed significantly positive correlation( P < 0. 05) with RWIQ; however,FIQ did not show any relation with RWIQ( P > 0. 05). Conclusion Brain type WD patients' intelligence structure has unbalanced damage,and fluid intelligence decreases more obviously than crystallized intelligence. The fluid intelligence and crystallized intelligence cannot replace with each other.
引文
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