周围神经损伤领域相关进展
摘要
<正>周围神经是连接效应器和中枢神经的枢纽,起着上传靶器官信号和下达中枢指令的枢纽作用。由于周围神经走行长、结构复杂及功能多样,一直以来都是临床与基础研究的热点。近年来,该领域研究取得了长足进展。一、解剖学领域1.功能解剖定位:通过对大量患者的体格检查和手术探查总结,目前临床上已基本确立了臂丛神经根的功能定位分工,具体如下:C5除支配上臂外侧感觉,同时支配冈上、下肌(肩胛上神经);胸大肌锁骨部小部分(胸外侧神经);三角肌(腋神经)
引文
[1] Creze M,Zaitouna M,Krystel NT,et al.Functional and structural microanatomy of the fetal sciatic nerve[J].Muscle Nerve,2017,56(4):787-796. DOI:10.1002/mus.25531.
[2] Delgado-Martínez I,Badia J,Pascual-Font A,et al.Fascicular topography of the human median nerve for neuroprosthetic surgery[J].Front Neurosci,2016,10:286. DOI:10.3389/fnins.2016.00286.
[3] Jabaley ME,Wallace WH,Heckler FR.Internal topography of major nerves of the forearm and hand:a current view[J].J Hand Surg Am,1980,5(1):1-18. DOI:10.1016/S0363-5023(80)80035- 9.
[4] Langer R,Vacanti JP,Vacanti CA,et al.Tissue engineering: biomedical applications[J].Tissue Eng,1995,1(2):151-161. DOI:10.1089/ten.1995.1.151.
[5] Johnson BN,Lancaster KZ,Zhen G,et al.3D printed anatomical nerve regeneration pathways[J].Adv Funct Mater,2015,25(39):6205- 6217. DOI:10.1002/adfm.201501760.
[6] Yan L,Guo Y,Qi J,et al.Iodine and freeze-drying enhanced high resolution Micro CT imaging for reconstructing 3D intraneural topo-graphy of human peripheral nerve fascicles[J].J Neurosci Me-thods,2017,287:58- 67. DOI:10.1016/j.jneumeth.2017.06.009.
[7] 顾立强.周围神经学组建设与学术进展[J].中国修复重建外科杂志,2018,32(7):786-788.
[8] 罗鹏,张毅,戚剑,等.周围神经虚拟三维重建中神经束功能及形态定位的组织化学染色方法研究[J].中国修复重建外科杂志,2012,26(4):477- 482. DOI:10.3760/cma.j.issn.1671-7600.2011.02.020.
[9] 张毅,刘小林,卢昊,等.周围神经功能束三维可视化中完整信息的二维全景图像获取[J].中华显微外科杂志,2010,33(4):319-321. DOI:10.3760/cma.j.issn.1001-2036.2010.04.022.
[10] 张毅,卢昊,何彩凤,等.周围神经功能束二维全景图像配准定位标志点的获取[J].中国组织工程研究与临床康复,2010,14(35):6566-6572. DOI:10.3969/j.issn.1673-8225.2010.35.027.
[11] 常景建,倪雪君.超声在周围神经损伤诊断和治疗中的应用进展[J].中国医学影像学技术,2017,33(11):1720-1723. DOI:10.13929/j.1003-3289.201704042.
[12] 周诗力,方向军.超声在周围神经病变中的应用进展[J].临床超声医学杂志,2018,20(6):412- 413.
[13] Neufeld EA,Shen PY,Nidecker AE,et al.MR imaging of the lumbosacral plexus:a review of techniques and pathologies[J].J Neuroimaging,2015,25(5):691-703. DOI:10.1111/jon.12253.
[14] Chhabra A,Rozen S,Scott K.Three-dimensional MR neurography of the lumbosacral plexus[J].Semin Musculoskelet Radiol,2017,19(2):149-159. DOI:10.1055/s- 0035-1545077.
[15] Jengojan S,Schellen C,Bodner G,et al.Imaging of the lumbosacral plexus:diagnostics and treatment planning with high-resolution procedures[J].Radiologe(German),2017,57(3):195-203. DOI:10.1007/s00117- 017- 0222-2.
[16] Wade RG,Itte V,Rankine JJ,et al.The diagnostic accuracy of 1.5T magnetic resonance imaging for detecting root avulsions in traumatic adult brachial plexus injuries[J].J Hand Surg Eur,2018,43(3):250-258. DOI:10.1177/1753193417729587.
[17] Bianchi ML,Padua L,Granata G,et al.Double site nerve lesion:ultrasound diagnosed musculocutaneous involvement in traumaticbrachial plexus injury[J].Clin Neurophysiol,2013,124(3):629- 630. DOI:10.1016/j.clinph.2012.07.015.
[18] Martín Noguerol T,Barousse R,Socolovsky M,et al.Quantitative magnetic resonance (MR) neurography for evaluation of peripheral nerves and plexus injuries[J].Quant Imaging Med Surg,2017,7(4):398- 421. DOI:10.21037/qims.2017.08.01.
[19] 顾玉东.臂丛神经损伤修复六条原则[J].中华手外科杂志,2015,31(5):321. DOI:10.3760/cma.j.issn.1005- 054X.2015.05.001.
[20] Wang SF,Li PC,Xue YH,et al.Contralateral C7 nerve transfer with direct coaptation to restore lower trunk function after traumatic brachial plexus avulsion[J].J Bone Joint Surg (Am),2013,95(9):821-827. DOI:10.2106/JBJS.L.00039.
[21] Li F,Wang SF,Li PC,et al.Restoration of active pick-up function in patients with total brachial plexus avulsion injuries[J].J Hand Surg (Eu),2018,43(3):269-274. DOI:10.1177/1753193417728405.
[22] 王树锋,薛云皓,栗鹏程,等.骨盆骨折致腰骶丛神经根损伤的临床分型—附36例手术探查报告[C].中华骨科杂志论坛,2012.
[23] 王树锋.健侧闭孔神经移位修复股神经重建腰骶丛撕脱伤患者的股四头肌功能[C].中国康复医学会修复重建外科专业委员会第19次全国学术交流会,2014.
[24] Li YC,Lin HD,Zhao L,et al.Unaffected contralateral S1 transfer for the treatment of lumbosacral plexus avulsion[J].Injury,2014,45(6):1015-1018. DOI:10.1016/j.injury.2014.01.014.
[25] 郑先友,朱弘一.胫神经比目鱼肌肌支移位重建腓总神经损伤[C].中华医学会骨科学分会第十九届骨科学会议暨第十二届国际COA学术大会,2017.
[26] Zheng MX,Hua XY,Feng JT,et al.Trial of contralateral seventh cervical nerve transfer for spastic arm paralysis[J].New Engl J Med,2018,378(1):22-34. DOI:10.1056/NEJMoa1615208.
[27] 王军,汤海艳,黄焕新,等.神经生长液改善老年帕金森病患者临床症状的评估[J].中华行为医学与脑科学杂志,2016,3:226-230. DOI:10.3760/cma.j.issn.1674- 6554.2016.03.007.
[28] Fernandez L,Komatsu DE,Gurevich M,et al.Emerging strategies on adjuvant therapies for nerve recovery[J].J Hand Surg Am,2018,43(4):368-373. DOI:10.1016/j.jhsa.2018.01.023.
[29] Safa B,Buncke G.Autograft substitutes:conduits and processed nerve allografts[J].Hand Clin,2016,32(2):127- 140. DOI:10.1016/j.hcl.2015.12.012.
[30] Zhu S,Liu J,Zheng C,et al.Analysis of human acellular nerve allograft reconstruction of 64 injured nerves in the hand and upper extremity:a 3 year follow-up study[J].J Tissue Eng Regen Med,2017,11(8):2314-2322. DOI:10.1002/term.2130.
[31] Gu Y,Zhu J,Xue C,et al.Chitosan/silk fibroin-based,Schwann cell-derived extracellular matrix-modified scaffolds for bridging rat sciatic nerve gaps[J].Biomaterials,2014,35(7):2253-2263. DOI:10.1016/j.biomaterials.2013.11.087.
[32] Yi S,Xu L,Gu X.Scaffolds for peripheral nerve repair and reconstruction[J].Exp Neurol,2018. DOI:10.1016/j.expneurol.2018.05.016.
[33] 苌彪,全琦,孙逊,等.周围神经损伤后瓦勒氏变性及神经导管的研究与进展[J].中国组织工程研究,2017,21(10):1596-1603. DOI:10.3969/j.issn.2095- 4344.2017.10.020.
[34] Qiu T,Yin Y,Li B,et al.PDLLA/PRGD/beta-TCP conduits build the neurotrophin-rich microenvironment suppressing the oxidative stress and promoting the sciatic nerve regeneration[J].J Biomed Mater Res A,2014,102(10):3734-3743. DOI:10.1002/jbm.a.35078.
[35] Zhang PX,Han N,Kou YH,et al.Peripheral nerve intersectional repair by bi-directional induction and systematic remodeling:biodegradable conduit tubulization from basic research to clinical application[J].Artif Cells Nanomed Biotechnol,2017,45(8):1464-1466. DOI:10.1080/21691401.2017.1373658.
[36] Henry BM,Vikse J,Sanna B,et al.Cervical rib prevalence and its association with thoracic outlet syndrome:a meta-analysis of 141 studies with surgical considerations[J].World Neurosurg,2018,110:e965-e978. DOI:10.1016/j.wneu.2017.11.148.
[37] Meyer P,Lintingre PF,Pesquer L,et al.The median nerve at the carpal tunnel and elsewhere[J].J Belg Soc Radiol,2018,102(1):17. DOI:10.5334/jbsr.1354.
[2] Delgado-Martínez I,Badia J,Pascual-Font A,et al.Fascicular topography of the human median nerve for neuroprosthetic surgery[J].Front Neurosci,2016,10:286. DOI:10.3389/fnins.2016.00286.
[3] Jabaley ME,Wallace WH,Heckler FR.Internal topography of major nerves of the forearm and hand:a current view[J].J Hand Surg Am,1980,5(1):1-18. DOI:10.1016/S0363-5023(80)80035- 9.
[4] Langer R,Vacanti JP,Vacanti CA,et al.Tissue engineering: biomedical applications[J].Tissue Eng,1995,1(2):151-161. DOI:10.1089/ten.1995.1.151.
[5] Johnson BN,Lancaster KZ,Zhen G,et al.3D printed anatomical nerve regeneration pathways[J].Adv Funct Mater,2015,25(39):6205- 6217. DOI:10.1002/adfm.201501760.
[6] Yan L,Guo Y,Qi J,et al.Iodine and freeze-drying enhanced high resolution Micro CT imaging for reconstructing 3D intraneural topo-graphy of human peripheral nerve fascicles[J].J Neurosci Me-thods,2017,287:58- 67. DOI:10.1016/j.jneumeth.2017.06.009.
[7] 顾立强.周围神经学组建设与学术进展[J].中国修复重建外科杂志,2018,32(7):786-788.
[8] 罗鹏,张毅,戚剑,等.周围神经虚拟三维重建中神经束功能及形态定位的组织化学染色方法研究[J].中国修复重建外科杂志,2012,26(4):477- 482. DOI:10.3760/cma.j.issn.1671-7600.2011.02.020.
[9] 张毅,刘小林,卢昊,等.周围神经功能束三维可视化中完整信息的二维全景图像获取[J].中华显微外科杂志,2010,33(4):319-321. DOI:10.3760/cma.j.issn.1001-2036.2010.04.022.
[10] 张毅,卢昊,何彩凤,等.周围神经功能束二维全景图像配准定位标志点的获取[J].中国组织工程研究与临床康复,2010,14(35):6566-6572. DOI:10.3969/j.issn.1673-8225.2010.35.027.
[11] 常景建,倪雪君.超声在周围神经损伤诊断和治疗中的应用进展[J].中国医学影像学技术,2017,33(11):1720-1723. DOI:10.13929/j.1003-3289.201704042.
[12] 周诗力,方向军.超声在周围神经病变中的应用进展[J].临床超声医学杂志,2018,20(6):412- 413.
[13] Neufeld EA,Shen PY,Nidecker AE,et al.MR imaging of the lumbosacral plexus:a review of techniques and pathologies[J].J Neuroimaging,2015,25(5):691-703. DOI:10.1111/jon.12253.
[14] Chhabra A,Rozen S,Scott K.Three-dimensional MR neurography of the lumbosacral plexus[J].Semin Musculoskelet Radiol,2017,19(2):149-159. DOI:10.1055/s- 0035-1545077.
[15] Jengojan S,Schellen C,Bodner G,et al.Imaging of the lumbosacral plexus:diagnostics and treatment planning with high-resolution procedures[J].Radiologe(German),2017,57(3):195-203. DOI:10.1007/s00117- 017- 0222-2.
[16] Wade RG,Itte V,Rankine JJ,et al.The diagnostic accuracy of 1.5T magnetic resonance imaging for detecting root avulsions in traumatic adult brachial plexus injuries[J].J Hand Surg Eur,2018,43(3):250-258. DOI:10.1177/1753193417729587.
[17] Bianchi ML,Padua L,Granata G,et al.Double site nerve lesion:ultrasound diagnosed musculocutaneous involvement in traumaticbrachial plexus injury[J].Clin Neurophysiol,2013,124(3):629- 630. DOI:10.1016/j.clinph.2012.07.015.
[18] Martín Noguerol T,Barousse R,Socolovsky M,et al.Quantitative magnetic resonance (MR) neurography for evaluation of peripheral nerves and plexus injuries[J].Quant Imaging Med Surg,2017,7(4):398- 421. DOI:10.21037/qims.2017.08.01.
[19] 顾玉东.臂丛神经损伤修复六条原则[J].中华手外科杂志,2015,31(5):321. DOI:10.3760/cma.j.issn.1005- 054X.2015.05.001.
[20] Wang SF,Li PC,Xue YH,et al.Contralateral C7 nerve transfer with direct coaptation to restore lower trunk function after traumatic brachial plexus avulsion[J].J Bone Joint Surg (Am),2013,95(9):821-827. DOI:10.2106/JBJS.L.00039.
[21] Li F,Wang SF,Li PC,et al.Restoration of active pick-up function in patients with total brachial plexus avulsion injuries[J].J Hand Surg (Eu),2018,43(3):269-274. DOI:10.1177/1753193417728405.
[22] 王树锋,薛云皓,栗鹏程,等.骨盆骨折致腰骶丛神经根损伤的临床分型—附36例手术探查报告[C].中华骨科杂志论坛,2012.
[23] 王树锋.健侧闭孔神经移位修复股神经重建腰骶丛撕脱伤患者的股四头肌功能[C].中国康复医学会修复重建外科专业委员会第19次全国学术交流会,2014.
[24] Li YC,Lin HD,Zhao L,et al.Unaffected contralateral S1 transfer for the treatment of lumbosacral plexus avulsion[J].Injury,2014,45(6):1015-1018. DOI:10.1016/j.injury.2014.01.014.
[25] 郑先友,朱弘一.胫神经比目鱼肌肌支移位重建腓总神经损伤[C].中华医学会骨科学分会第十九届骨科学会议暨第十二届国际COA学术大会,2017.
[26] Zheng MX,Hua XY,Feng JT,et al.Trial of contralateral seventh cervical nerve transfer for spastic arm paralysis[J].New Engl J Med,2018,378(1):22-34. DOI:10.1056/NEJMoa1615208.
[27] 王军,汤海艳,黄焕新,等.神经生长液改善老年帕金森病患者临床症状的评估[J].中华行为医学与脑科学杂志,2016,3:226-230. DOI:10.3760/cma.j.issn.1674- 6554.2016.03.007.
[28] Fernandez L,Komatsu DE,Gurevich M,et al.Emerging strategies on adjuvant therapies for nerve recovery[J].J Hand Surg Am,2018,43(4):368-373. DOI:10.1016/j.jhsa.2018.01.023.
[29] Safa B,Buncke G.Autograft substitutes:conduits and processed nerve allografts[J].Hand Clin,2016,32(2):127- 140. DOI:10.1016/j.hcl.2015.12.012.
[30] Zhu S,Liu J,Zheng C,et al.Analysis of human acellular nerve allograft reconstruction of 64 injured nerves in the hand and upper extremity:a 3 year follow-up study[J].J Tissue Eng Regen Med,2017,11(8):2314-2322. DOI:10.1002/term.2130.
[31] Gu Y,Zhu J,Xue C,et al.Chitosan/silk fibroin-based,Schwann cell-derived extracellular matrix-modified scaffolds for bridging rat sciatic nerve gaps[J].Biomaterials,2014,35(7):2253-2263. DOI:10.1016/j.biomaterials.2013.11.087.
[32] Yi S,Xu L,Gu X.Scaffolds for peripheral nerve repair and reconstruction[J].Exp Neurol,2018. DOI:10.1016/j.expneurol.2018.05.016.
[33] 苌彪,全琦,孙逊,等.周围神经损伤后瓦勒氏变性及神经导管的研究与进展[J].中国组织工程研究,2017,21(10):1596-1603. DOI:10.3969/j.issn.2095- 4344.2017.10.020.
[34] Qiu T,Yin Y,Li B,et al.PDLLA/PRGD/beta-TCP conduits build the neurotrophin-rich microenvironment suppressing the oxidative stress and promoting the sciatic nerve regeneration[J].J Biomed Mater Res A,2014,102(10):3734-3743. DOI:10.1002/jbm.a.35078.
[35] Zhang PX,Han N,Kou YH,et al.Peripheral nerve intersectional repair by bi-directional induction and systematic remodeling:biodegradable conduit tubulization from basic research to clinical application[J].Artif Cells Nanomed Biotechnol,2017,45(8):1464-1466. DOI:10.1080/21691401.2017.1373658.
[36] Henry BM,Vikse J,Sanna B,et al.Cervical rib prevalence and its association with thoracic outlet syndrome:a meta-analysis of 141 studies with surgical considerations[J].World Neurosurg,2018,110:e965-e978. DOI:10.1016/j.wneu.2017.11.148.
[37] Meyer P,Lintingre PF,Pesquer L,et al.The median nerve at the carpal tunnel and elsewhere[J].J Belg Soc Radiol,2018,102(1):17. DOI:10.5334/jbsr.1354.