早期中药退黄外洗方药浴干预新生儿黄疸疗效观察
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摘要
目的:观察早期中药退黄外洗方药浴干预新生儿黄疸的临床效果。方法:将新生儿100例分为对照组和观察组各50例。对照组予常规干预,观察组早期予中药退黄外洗方药浴干预,比较新生儿血清胆红素值、黄疸发生情况、第1次排胎粪时间及胎粪转黄时间。结果:新生儿黄疸发生率对照组为62.0%,观察组为22.0%,观察组低于对照组;观察组第1次排胎粪时间、胎粪转黄时间早于对照组,差异有统计学意义(P<0.05)。结论:早期中药退黄外洗方药浴预防新生儿黄疸效果优于常规干预。
Objective: To observe clinical effects of medicated bath of Tuihuang Waixi prescription in early intervention for neonatal jaundice. Methods: All 100 neonates were allocated to the control group and the observation group, 50 cases each group. The control group accepted conventional intervention, and the observation group medicated bath of TuiHuang WaiXi prescription early, to compare cholinergic value, the incidence of jaundice,the first time of discharging meconium and the time of meconium yellowing. Results: The incidence of neonatal jaundice in the control group was 62.0%, higher than 22.0% of the observation group(P<0.05), and the observation group was earlier than the control group in the first time of discharging meconium and the time of meconium yellowing, and the difference showed statistical meaning(P<0.05). Conclusion: Early intervention by medicated bath of TuiHuang WaiXi prescription is superior to conventional intervention in the prevention of neonatal jaundice.
Objective: To observe clinical effects of medicated bath of Tuihuang Waixi prescription in early intervention for neonatal jaundice. Methods: All 100 neonates were allocated to the control group and the observation group, 50 cases each group. The control group accepted conventional intervention, and the observation group medicated bath of TuiHuang WaiXi prescription early, to compare cholinergic value, the incidence of jaundice,the first time of discharging meconium and the time of meconium yellowing. Results: The incidence of neonatal jaundice in the control group was 62.0%, higher than 22.0% of the observation group(P<0.05), and the observation group was earlier than the control group in the first time of discharging meconium and the time of meconium yellowing, and the difference showed statistical meaning(P<0.05). Conclusion: Early intervention by medicated bath of TuiHuang WaiXi prescription is superior to conventional intervention in the prevention of neonatal jaundice.
引文
[1]刘艳龙,刘铁莲.血清白蛋白、非结合胆红素检测在新生儿黄疸中的临床应用价值研究[J].中国实验诊断学,2012,16(6):1120-1121.
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[3]陈昌辉,李茂军,吴青,等.新生儿黄疸的诊断和治疗[J].现代临床医学,2013,39(2):154-160.
[4]曹巧玲.综合护理干预在改善新生儿黄疸预后中的应用[J].中国生化药物杂志,2017,37(8):295-297.
[5]董孝云,师淑锋,张璋.白蛋白联合蓝光照射治疗新生儿黄疸疗效及临床指标观察[J].中国卫生标准管理,2016,7(3):93-94.
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[9]彭武,杨琍琦,刘亢亢.新生儿病理性黄疸程度与血红蛋白、血细胞比容的关系研究[J].齐齐哈尔医学院学报,2017,38(13):1505-1506.
[10]刘小姣,李堰松.GSH联合早期护理干预对新生儿黄疸的疗效分析[J].国际检验医学杂志,2016,37(23):3308-3310.
[11]郭雯雯,胡子衡,孟娜娜,等.加减保产无忧方预防新生儿黄疸的临床应用研究[J].河北中医,2018,40(11):1656-1659.
[12]朱更娣,陈雨琴,马风桐.茵栀黄口服液干预早期新生儿黄疸52例临床观察[J].河北中医,2015,37(11):1713-1714.
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[14]秦俊,周四芳,王瑜,等.光疗对高未结合胆红素血症新生儿细胞免疫功能的影响[J].实用儿科临床杂志,2012,27(8):614-616.
[15]马加宝,陈凯.临床新生儿学[M].济南:山东科学技术出版社,2003:81.
[16]崔忠,孙媛.早期综合干预预防新生儿高胆红素血症[J].中国新生儿科杂志,2008,23(1):47-48.
[17]Kumar K,Sohaila A,Tikmani SS,et al.Screening for G6PD deficiency among neonates with neonatal jaundice admitted to tertiary care center:a need in disguise[J].J Coll Physicians Surg Pak,2015,25(8):625-626.
[18]Mreihil K,Madsen P,Nakstad B,et al.Early formation of bilirubin isomers during phototherapy for neonatal jaundice:effects of single vs.double fluorescent lamps vs.photodiodes[J].Pediatr Res,2015,78(1):56-62.
[19]史玉琴,岳雄,高红霞,等.中药外洗方治疗新生儿黄疸疗效观察[J].西部中医药,2018,31(9):112-114.
[20]王忠厚.新生儿退黄洗液对新生儿黄疸的早期干预效果[J].中国医药指南,2013,11(6)263-264.
[21]赵丹丹,黄迪,高翔羽.经皮胆红素测定在新生儿黄疸中的应用[J].中华儿科杂志,2017,55(1):74-77.
[22]王洁,周海红,吴珺瑛.预防早产儿高胆红素血症的临床实践[J].山西大同大学学报:自然科学版,2011,27(6):52-53.
[2]中华医学会儿科学分会新生儿学组.新生儿高胆红素血症诊断和治疗专家共识[J].中华儿科杂志,2014,52(10):745-748.
[3]陈昌辉,李茂军,吴青,等.新生儿黄疸的诊断和治疗[J].现代临床医学,2013,39(2):154-160.
[4]曹巧玲.综合护理干预在改善新生儿黄疸预后中的应用[J].中国生化药物杂志,2017,37(8):295-297.
[5]董孝云,师淑锋,张璋.白蛋白联合蓝光照射治疗新生儿黄疸疗效及临床指标观察[J].中国卫生标准管理,2016,7(3):93-94.
[6]李少芬.优质护理干预在新生儿黄疸中的应用[J].辽宁医学杂志,2015,29(1):49-50.
[7]高玉芳,魏丽丽.临床实用护理技术及常见并发症处理[M].北京:人民军医出版社,2014:10.
[8]王秀菊,武金起,李月梅.新生儿高胆红素血症的影响因素分析[J].中国妇幼健康研究2015,28(1):125-126.
[9]彭武,杨琍琦,刘亢亢.新生儿病理性黄疸程度与血红蛋白、血细胞比容的关系研究[J].齐齐哈尔医学院学报,2017,38(13):1505-1506.
[10]刘小姣,李堰松.GSH联合早期护理干预对新生儿黄疸的疗效分析[J].国际检验医学杂志,2016,37(23):3308-3310.
[11]郭雯雯,胡子衡,孟娜娜,等.加减保产无忧方预防新生儿黄疸的临床应用研究[J].河北中医,2018,40(11):1656-1659.
[12]朱更娣,陈雨琴,马风桐.茵栀黄口服液干预早期新生儿黄疸52例临床观察[J].河北中医,2015,37(11):1713-1714.
[13]林一霞,王颖慧,李志宏.新生儿重症高胆红素血症危险因素临床分析[J].现代中西医结合杂志,2013,22(22):2424-2426.
[14]秦俊,周四芳,王瑜,等.光疗对高未结合胆红素血症新生儿细胞免疫功能的影响[J].实用儿科临床杂志,2012,27(8):614-616.
[15]马加宝,陈凯.临床新生儿学[M].济南:山东科学技术出版社,2003:81.
[16]崔忠,孙媛.早期综合干预预防新生儿高胆红素血症[J].中国新生儿科杂志,2008,23(1):47-48.
[17]Kumar K,Sohaila A,Tikmani SS,et al.Screening for G6PD deficiency among neonates with neonatal jaundice admitted to tertiary care center:a need in disguise[J].J Coll Physicians Surg Pak,2015,25(8):625-626.
[18]Mreihil K,Madsen P,Nakstad B,et al.Early formation of bilirubin isomers during phototherapy for neonatal jaundice:effects of single vs.double fluorescent lamps vs.photodiodes[J].Pediatr Res,2015,78(1):56-62.
[19]史玉琴,岳雄,高红霞,等.中药外洗方治疗新生儿黄疸疗效观察[J].西部中医药,2018,31(9):112-114.
[20]王忠厚.新生儿退黄洗液对新生儿黄疸的早期干预效果[J].中国医药指南,2013,11(6)263-264.
[21]赵丹丹,黄迪,高翔羽.经皮胆红素测定在新生儿黄疸中的应用[J].中华儿科杂志,2017,55(1):74-77.
[22]王洁,周海红,吴珺瑛.预防早产儿高胆红素血症的临床实践[J].山西大同大学学报:自然科学版,2011,27(6):52-53.