龙牡汤治疗青年特应性皮炎的临床疗效及其对患者生活质量的影响
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摘要
目的探讨龙牡汤治疗青年特应性皮炎的临床疗效及其对患者生活质量的影响。方法选取晋江市医院2016年2月—2017年2月收治的青年及成人期特应性皮炎患者60例,采用双盲法分为对照组与观察组,各30例。对照组患者行常规治疗,观察组患者在对照组基础上予以中药龙牡汤治疗,均连续治疗8周。比较两组患者临床疗效、皮肤病生活质量指标调查表(DLQI)评分,并观察两组患者不良反应发生情况。结果观察组患者临床疗效优于对照组(P<0.05)。治疗前两组患者DLQI评分比较,差异无统计学意义(P>0.05);治疗后观察组患者DLQI评分低于对照组(P<0.05)。两组患者不良反应发生率比较,差异无统计学意义(P>0.05)。结论龙牡汤治疗青年特应性皮炎的临床疗效确切,可提高患者生活质量,且安全性较高。
Objective To study the clinical effect of Longmu decoction on young and adult atopic dermatitis and the impact on patient's quality of life.Methods A total of 60 cases of patients with young and adult atopic dermatitis were selected from February 2016 to February 2017 in Jinjiang City Hospital,which were divided into control group and observation group by double blind method,30 cases in each group.The control group was treated with routine treatment,the observation group was treated with Longmu decoction based on control group.Clinical effect,DLQI score were compared between the two groups,and the incidence of adverse reactions were observed.Results The clinical effect in observation group was better than control group(P<0.05).There was no significant difference in DLQI score between the two groups before treatment(P>0.05).After treatment,the DLQI score of the observation group was lower than control group(P<0.05).There was no significant difference incidence rate of adverse reactions between the two groups(P>0.05). Conclusion Longmu decoction have an exact clinical effect for young and adult atopic dermatitis,it can improve the quality of life of patients,and with high safety.
Objective To study the clinical effect of Longmu decoction on young and adult atopic dermatitis and the impact on patient's quality of life.Methods A total of 60 cases of patients with young and adult atopic dermatitis were selected from February 2016 to February 2017 in Jinjiang City Hospital,which were divided into control group and observation group by double blind method,30 cases in each group.The control group was treated with routine treatment,the observation group was treated with Longmu decoction based on control group.Clinical effect,DLQI score were compared between the two groups,and the incidence of adverse reactions were observed.Results The clinical effect in observation group was better than control group(P<0.05).There was no significant difference in DLQI score between the two groups before treatment(P>0.05).After treatment,the DLQI score of the observation group was lower than control group(P<0.05).There was no significant difference incidence rate of adverse reactions between the two groups(P>0.05). Conclusion Longmu decoction have an exact clinical effect for young and adult atopic dermatitis,it can improve the quality of life of patients,and with high safety.
引文
[1]赵一丁,姚春海,朗娜,等.龙牡汤治疗青年及成人期特应性皮炎的疗效观察及生活质量评价[J].中国中西医结合皮肤性病学杂志,2011,10(4):215-218.
[2]雍磊,高春芳,程相铎,等.淋巴免疫治疗成人特应性皮炎临床疗效及安全性[J].中华皮肤科杂志,2015,48(1):19-23.
[3]梁宝莹,宋丽芬,熊述清,等.中药熏洗联合NB-UVB治疗特应性皮炎的临床分析[J].中国中医药现代远程教育,2017,15(13):140-143.
[4]曲靖.加味龙牡二妙汤治疗湿热蕴肤型湿疹的临床疗效及安全性分析[J].中医临床研究,2017,9(5):126-127.
[5]苏湘川,任小丽,石青青.Th17细胞及相关细胞因子与不同严重程度特应性皮炎的相关性研究[J].中国中西医结合皮肤性病学杂志,2015,14(5):293-294.
[6]唐苏为,谢韶琼,宋勋,等.成人期特应性皮炎的研究现状[J].海南医学,2016,27(8):1305-1307.
[7]姜丽亚,郭震,戴景斌,等.益生菌治疗成人特应性皮炎疗效评价[J].中国麻风皮肤病杂志,2014,23(4):205-207.
[8]薛亮,迮侃,王一飞.张明教授滋阴凉血法治疗成人特应性皮炎证治经验[J].河北中医,2017,39(3):329-331.
[9]全小红,陈秀华,成沈荣.特应性皮炎患者外周血总IgE和T淋巴细胞亚群与中医证候的相关性探讨[J].中华中医药杂志,2016,23(5):1723-1725.
[2]雍磊,高春芳,程相铎,等.淋巴免疫治疗成人特应性皮炎临床疗效及安全性[J].中华皮肤科杂志,2015,48(1):19-23.
[3]梁宝莹,宋丽芬,熊述清,等.中药熏洗联合NB-UVB治疗特应性皮炎的临床分析[J].中国中医药现代远程教育,2017,15(13):140-143.
[4]曲靖.加味龙牡二妙汤治疗湿热蕴肤型湿疹的临床疗效及安全性分析[J].中医临床研究,2017,9(5):126-127.
[5]苏湘川,任小丽,石青青.Th17细胞及相关细胞因子与不同严重程度特应性皮炎的相关性研究[J].中国中西医结合皮肤性病学杂志,2015,14(5):293-294.
[6]唐苏为,谢韶琼,宋勋,等.成人期特应性皮炎的研究现状[J].海南医学,2016,27(8):1305-1307.
[7]姜丽亚,郭震,戴景斌,等.益生菌治疗成人特应性皮炎疗效评价[J].中国麻风皮肤病杂志,2014,23(4):205-207.
[8]薛亮,迮侃,王一飞.张明教授滋阴凉血法治疗成人特应性皮炎证治经验[J].河北中医,2017,39(3):329-331.
[9]全小红,陈秀华,成沈荣.特应性皮炎患者外周血总IgE和T淋巴细胞亚群与中医证候的相关性探讨[J].中华中医药杂志,2016,23(5):1723-1725.