摘要
目的:观察黄芪建中丸联合奥美拉唑治疗脾胃虚寒型胃溃疡的临床疗效。方法:选取本院100例脾胃虚寒型胃溃疡患者,随机分为对照组(奥美拉唑组)和试验组(合奥美拉唑联合黄芪建中丸组),治疗4周。结果:对照组患者痊愈20例,显著有效15例,治疗总有效率为70%;试验组痊愈30例,显著有效17例,总有效率为94%,两组相比差异具有统计学意义(P<0.05);胃溃疡的主要症状明显得到缓解,差异均具有统计学意义(P<0.05);对照组和试验组的Hp清除率分别为78%、56%,差异具有统计学意义(P<0.05)。结论:黄芪建中丸联合奥美拉唑治疗脾胃虚寒型胃溃疡比单用奥美拉唑疗效更好。
AIM:To observe the clinical effect of HuangqiJianzhong pill combined with omeprazole on gastric ulcer of deficiency cold of spleen and stomach type.METHODS:100cases gastric ulcer of deficiency cold of spleen and stomach type from our hospital were chose,who were randomly divided into two groups:the control group(omeprazole)and the experimental group(HuangqiJianzhong pill and omeprazole),treatment lasted for 4weeks.RESULTS:20cases in the control group were fully recovered,remarkably effective:15cases,the total effective rate was 70%;30 cases in the experimental group were fully recovered,remarkably effective:17cases,the total effective rate was 94%,there was statistically significant difference(P<0.05).Compared with the control group,the main symptoms of gastric ulcer in the experimental group were significantly reduced,there was statistically significant difference(P <0.05).The rate of Hp clearance was 78% and56%in the control group and the experimental group,there was statistically significant difference(P<0.05).CONCLUSION:The effect using HuangqiJianzhong pill combined with omeprazole for the treatment gastric ulcer of deficiency cold of spleen and stomach type is better than omeprazole alone.
引文
[1]姚永莉,张万岱.幽门螺旋杆菌与胃癌的关系[J].世界华人消化杂志,2011,9(9):1045-1049.
[2]陶国水.消化性溃疡中医诊治经验[J].世界中医药,2011,6(4):329-331.
[3]王洪京,张春梅.消化性溃疡中医证型及客观化研究进展[J].山东中医,2005.24(2):124-125.
[4]李益农.消化性溃疡药物治疗的最新进展[J].中国实用内科志,2010,20(11):131-132.
[5]刘中宏,王秀江,马香华.泮托拉唑与奥美拉唑治疗胃溃疡的疗效观察[J].中国基层医药,2002,9(2):111-112.
[6]殷文银,尹玉平.中药分期联合西药治疗消化性溃疡98例[J].中国中医急症,2012,21(4):664-665.
[7]Nguyen LT,Uchida T,Tsukamoto Y,et al.Evaluation of rapid urine test for the detection of helicobacter pylori infection in the Vietnamese popolation[J].Dig Dis Sci,2010,55(1):89-93.
[8]李见好.幽门螺旋杆菌阳性消化性溃疡的治疗及护理效果观察[J].全科护理,2013,11(8):2137-2138.
[9]姚洁.复方丹参滴丸联合奥美拉唑治疗老年胃溃疡95例疗效观察[J].重庆医学,2012,37(23):2733-2734.