三氟乙胺盐酸盐在药物化学中的应用
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摘要
三氟乙胺盐酸盐在药物合成中应用广泛。本文介绍了三氟乙胺盐酸盐的概况,对其在药物合成中的应用进行了综述。
Trifluoroethylamine hydrochloride is widely used in drug synthesis. This paper introduces the general situation of trifluoroethylamine hydrochloride and its application in drug synthesi.
Trifluoroethylamine hydrochloride is widely used in drug synthesis. This paper introduces the general situation of trifluoroethylamine hydrochloride and its application in drug synthesi.
引文
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[2]Anderson E,Jiang X.et al.Antioxidant inflammation modulators:oleanolic acid derivatives with saturation in the C-ring:US,20100056777[P].2010-03-04.
[3]Jiang X,Liu X.Antioxidant inflammation modulators:C-17 homologated oleanolic acid derivatives:WO,2009129548[P].2009-10-22.
[4]Wei C C,Angehrn P.Cephalosporin antibiotics:US,5523400[P].1996-06-04.
[5]Angehrn P,Wei C C.Cephalosporin derivatives:EP,620225[P].1994-10-19.
[6]Breuer H,Treuner U D.Trifluoroalkylureido 3-heterocyclic thio methyl cephalosporins:US,4092475[P].1978-05-30.
[7]Casarez A,Chaudhary K.Antiviral phosphinate compounds:WO,2008005565[P].2008-01-10.
[8]Gauthier D R,Ikemoto N.Total synthesis of a second generation HIV protease inhibitor[J].Tetrahedron:Asymmetry,2003,14(22):3557-3567.
[9]Miller R A,Karady S.Piperazine carboxamide intermediates of HIV protease inhibitors and processes for their preparation:US,20030191121[P].2003-10-09.
[10]Ikemoto N,Liu J.Process for preparing piperazinepentaneamide HIV protease inhibitors:US,20030144512[P].2003-07-31.
[11]Fleitz F J,Petrillo D E.Hydrohalide salts of an HIV protease inhibitor:US,20030125336[P].2003-07-03.
[12]Karki S B.HIV protease inhibitors supported on cation exchange resins for oral administration:WO,2002067683[P].2002-09-06.
[13]Yu K L,Wang X.Substituted 2-methyl-benzimidazole respiratory syncytial virus antiviral agents:WO,2003053344[P].2003-07-03.
[14]Yu K L,Civiello R L.Heterocyclic substituted 2-methylbenzimidazole antiviral agents:US,20020099208[P].2003-07-25.
[15]Yu K L,Wang X.Imidazopyridine and imidazopyrimidine antiviral agents:WO,2001095910[P].2001-12-20.
[16]Anand N K,Baik T G.Benzoxazepines as inhibitors of mTOR and their use to treat cancer:WO,2010135568[P].2010-11-25.
[17]Giannini G,Cabri W.5-phenylisoxazole-3-carboxamides modulating Hsp90 with antitumor activity:WO,2010000748[P].2010-01-07.
[18]Chen L,Han X C.Spiroindolinone derivatives:US,20090163512[P].2009-06-25.
[19]Ding Q J,Jiang N.Spiroindolinone derivatives:US,20090156610[P].2009-06-18.
[20]Binch H,Young S.Aminopyrimidines useful as kinase inhibitors:WO,2008128009[P].2008-10-23.
[21]Axten J M,Bryan D L.Anthranilamide inhibitors of aurora kinase:WO,2008092049[P].2008-07-31.
[22]Magnuson S,Dixon J.Pyrrolo triazine derivatives useful for treating cancer through inhibition of aurora kinase:WO,2007064932[P].2007-06-07.
[23]Mortlock A A,Keen N J.Quinazoline derivatives and their use as pharmaceuticals:WO,2001021596[P].2001-03-29.
[24]Mortlock A A,Keen N J.Quinazoline derivatives:WO,2001021595[P].2001-03-29.
[25]Dumont J A,Bitonti A J.6,9-disubstituted 2-[trans-(4-aminocyclohexyl)amino]purines:WO,9943676[P].1999-09-02.
[26]Guy R K,Zhu F.Substituted 2-alkyl-1-oxo-n-phenyl-3-heteroaryl-1,2,3,4-tetrahy droisoquinoline-4-carboxamides for antimalarial therapies:WO,2013027196[P].2013-02-28.
[27]Itoh K,Okonogi K.Azole compounds,their production and use:EP,510700[P].1992-10-28.
[28]Chaudhari S S,Thomas A.Fused imidazole carboxamides as TRPV3 modulators:US,20100152192[P].2010-06-17.
[29]Jones D F,Oldham K.Heterocyclic derivatives:EP,60697[P].1982-09-22.
[30]Brackley J A III,Shaw A N.Prolyl hydroxylase inhibitors:WO,2009158315[P].2009-12-30.