无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并2型糖尿病效果及安全性
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摘要
目的总结并分析慢性阻塞性肺疾病急性加重期合并2型糖尿病患者应用无创呼吸机治疗的临床效果及治疗安全性。方法 50例样本分析对象都是2017年1月—2018年10月在该医院进行治疗的慢性阻塞性肺疾病急性加重期合并2型糖尿病患者,以计算机表法实现各组处理。试验组(n=25例)选择无创呼吸机治疗,对照组(n=25例)进行常规治疗,比较两组患者的治疗效果及治疗安全性。结果该实验探究中试验组患者的血糖指标:糖化血红蛋白(6.41±0.56)%(t=6.025 4,P=0.000 0)、餐后2 h血糖(6.21±1.44)mmol/L(t=6.087 2,P=0.000 0)、空腹血糖(9.48±1.55)mmol/L(t=7.471 4,P=0.000 0);肺功能指标:第1秒用力呼气容积(65.23±11.65)%(t=3.884 5,P=0.000 0)、FEV1/FVC(93.61±4.14)(t=12.138 2,P=0.000 0)、FEV1(5.61±0.46)L(t=22.2251,P=0.000 0);血气指标:动脉血二氧化碳分压(46.55±6.32)mmHg(t=10.293 2,P=0.000 0)、动脉血氧分压(73.94±6.61)mmHg(t=8.593 3,P=0.000 0)、pH(7.44±0.56)(t=12.728 9,P=0.000 0);住院天数:(15.78±3.42)d (t=10.701 9,P=0.000 0)、住院费用(5347.62±289.96)元(t=25.156 4,P=0.000 0)与对照组患者相比均差异有统计学意义(P<0.05)。结论接受无创呼吸机治疗的慢性阻塞性肺疾病急性加重期合并2型糖尿病患者,能够提升患者的临床治疗效果,改善患者的血气指标情况以及维持血糖值在合理的范围之内,并能够改善患者的肺功能,减少住院时间以及治疗费用。
Objective To summarize and analyze the clinical efficacy and safety of non-invasive ventilator in patients with acute exacerbation of chronic obstructive pulmonary disease and type 2 diabetes. Methods Fifty samples were analyzed for patients with acute exacerbation of chronic obstructive pulmonary disease and type 2 diabetes mellitus who were treated in our hospital from January 2017 to February 2018. All groups were treated by computerized method. The experimental group(n=25 cases) was treated with non-invasive ventilator, and the control group(n=25 cases) was treated routinely. The therapeutic effect and treatment safety of the two groups were compared. Results This experiment explored the blood glucose indexes of the patients in the experimental group: glycated hemoglobin(6.41±0.56)%(t=6.0254, P=0.000 0), and postprandial blood glucose(6.21±1.44) mmol/L(t=6.087 2, P=0.000 0), fasting blood glucose(9.48±1.55)mmol/L(t=7.471 4, P=0.000 0); pulmonary function index: forced expiratory volume in the first second(65.23±11.65)%(t=3.884 5, P=0.000 0), FEV1/FVC(93.61±4.1 4)(t=12.138 2, P=0.000 0), FEV1(5.61±0.46) L(t=22.2251, P=0.0000); blood gas index: arterial blood carbon dioxide partial pressure(46.55±6.32) mmHg(t=10.293 2, P=0.000 0),arterial oxygen partial pressure(73.94±6.61) mmHg(t=8.593 3, P=0.000 0), pH(7.44±0.56)(t=12.728 9, P=0.000 0);hospitalization days:(15.78±3.42) days(t=10.701 9, P=0.000 0), hospitalization expenses(5 347.62±289.96) yuan(t=25.156 4, P=0.000 0) were compared with the control group, and the difference was statistically significant(P<0.05).Conclusion Patients with acute exacerbation of chronic obstructive pulmonary disease treated with non-invasive ventilator combined with type 2 diabetes can improve the clinical treatment of patients, improve the blood gas index of patients and maintain the blood glucose level within a reasonable range, and can improve patient's lung function and reduce hospital stay and treatment costs.
Objective To summarize and analyze the clinical efficacy and safety of non-invasive ventilator in patients with acute exacerbation of chronic obstructive pulmonary disease and type 2 diabetes. Methods Fifty samples were analyzed for patients with acute exacerbation of chronic obstructive pulmonary disease and type 2 diabetes mellitus who were treated in our hospital from January 2017 to February 2018. All groups were treated by computerized method. The experimental group(n=25 cases) was treated with non-invasive ventilator, and the control group(n=25 cases) was treated routinely. The therapeutic effect and treatment safety of the two groups were compared. Results This experiment explored the blood glucose indexes of the patients in the experimental group: glycated hemoglobin(6.41±0.56)%(t=6.0254, P=0.000 0), and postprandial blood glucose(6.21±1.44) mmol/L(t=6.087 2, P=0.000 0), fasting blood glucose(9.48±1.55)mmol/L(t=7.471 4, P=0.000 0); pulmonary function index: forced expiratory volume in the first second(65.23±11.65)%(t=3.884 5, P=0.000 0), FEV1/FVC(93.61±4.1 4)(t=12.138 2, P=0.000 0), FEV1(5.61±0.46) L(t=22.2251, P=0.0000); blood gas index: arterial blood carbon dioxide partial pressure(46.55±6.32) mmHg(t=10.293 2, P=0.000 0),arterial oxygen partial pressure(73.94±6.61) mmHg(t=8.593 3, P=0.000 0), pH(7.44±0.56)(t=12.728 9, P=0.000 0);hospitalization days:(15.78±3.42) days(t=10.701 9, P=0.000 0), hospitalization expenses(5 347.62±289.96) yuan(t=25.156 4, P=0.000 0) were compared with the control group, and the difference was statistically significant(P<0.05).Conclusion Patients with acute exacerbation of chronic obstructive pulmonary disease treated with non-invasive ventilator combined with type 2 diabetes can improve the clinical treatment of patients, improve the blood gas index of patients and maintain the blood glucose level within a reasonable range, and can improve patient's lung function and reduce hospital stay and treatment costs.
引文
[1]黎月莲.家庭应用无创呼吸机治疗慢性阻塞性肺疾病急性加重期并Ⅱ型呼吸衰竭的临床研究[J].广西医学,2016, 38(2):282-284.
[2]董学敏,王斐.慢性阻塞性肺疾病急性加重期合并呼吸衰竭30例患者应用无创呼吸机治疗的护理[J].中华肺部疾病杂志:电子版,2016(1):109-110.
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[4]刘萍,王丰.无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭的疗效观察[C]//中国中药杂志/专集:,基层医疗机构从业人员科技论文写作培训会议.中国中药杂志,2016.
[5]刘利娟.中药配合无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭疗效观察[J].河北中医,2016, 38(8):1155-1157.
[6]黄安,吴飞,江志辉.纳洛酮联合无创呼吸机在慢性阻塞性肺疾病急性加重期合并呼吸衰竭患者中的应用[J].基层医学论坛, 2016, 25(17):347-349.
[7]张晓波,窦海艳.丹红注射液联合无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并II型呼吸衰竭80例疗效评价[J].辽宁中医杂志, 2017(2):304-306.
[8]张爱萍.无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭的临床观察[J].中西医结合心血管病电子杂志, 2016, 4(29):89-90.
[9]刘云.无创呼吸机治疗慢性阻塞性肺疾病急性加重合并Ⅱ型呼吸衰竭52例临床分析[J].中国当代医药, 2017,24(1):29-31.
[10]邵伯云,周维华,朱伯金,等.无创呼吸机联合纳洛酮治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭的疗效观察[J].疑难病杂志, 2017, 16(1):40-43.
[2]董学敏,王斐.慢性阻塞性肺疾病急性加重期合并呼吸衰竭30例患者应用无创呼吸机治疗的护理[J].中华肺部疾病杂志:电子版,2016(1):109-110.
[3]苏荣叶.无创呼吸机治疗老年慢性阻塞性肺疾病急性加重期合并呼吸衰竭的效果观察[J].临床合理用药杂志, 2016, 9(35):110-111.
[4]刘萍,王丰.无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭的疗效观察[C]//中国中药杂志/专集:,基层医疗机构从业人员科技论文写作培训会议.中国中药杂志,2016.
[5]刘利娟.中药配合无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭疗效观察[J].河北中医,2016, 38(8):1155-1157.
[6]黄安,吴飞,江志辉.纳洛酮联合无创呼吸机在慢性阻塞性肺疾病急性加重期合并呼吸衰竭患者中的应用[J].基层医学论坛, 2016, 25(17):347-349.
[7]张晓波,窦海艳.丹红注射液联合无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并II型呼吸衰竭80例疗效评价[J].辽宁中医杂志, 2017(2):304-306.
[8]张爱萍.无创呼吸机治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭的临床观察[J].中西医结合心血管病电子杂志, 2016, 4(29):89-90.
[9]刘云.无创呼吸机治疗慢性阻塞性肺疾病急性加重合并Ⅱ型呼吸衰竭52例临床分析[J].中国当代医药, 2017,24(1):29-31.
[10]邵伯云,周维华,朱伯金,等.无创呼吸机联合纳洛酮治疗慢性阻塞性肺疾病急性加重期合并Ⅱ型呼吸衰竭的疗效观察[J].疑难病杂志, 2017, 16(1):40-43.