磁共振磁敏感加权成像诊断不同类别早期前列腺癌的价值
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摘要
目的研究磁共振磁敏感加权成像(SWI)对不同类别早期前列腺癌诊断的临床价值。方法纳入2017年6月—2018年6月期间收治的30例前列腺癌患者作为研究组,所有患者均进行前列腺特异性抗原(PSA)检测,根据PSA值范围分为不同组别,其中0-4 ng/m L为A组(9例)、4～10 ng/m L为B组(13例),> 10 ng/m L分为C组(8例)。另选取同期收治的30例前列腺增生患者作为对照组。所有患者均进行磁共振磁敏感加权成像检查,观察所得图像,分析磁共振磁敏感加权成像对不同类别早期前列腺癌诊断的临床价值。结果四组患者Ve水平无差异,P> 0. 05; C组Sus E评分、Ktrans以及Kep水平均高于B组,B组高于A组,A组高于对照组,均P <0. 05。早期前列腺癌患者Sus E评分与Ktrans、Kep水平呈正相关,P <0. 05;与Ve水平无相关性,P> 0. 05。结论磁共振磁敏感加权成像对前列腺癌诊断效果较好,能有效鉴别诊断早期不同类别前列腺癌,对临床诊断前列腺癌及评估治疗效果具有重要意义。
Ojbective To study the advantages and clinical value of magnetic resonance susceptibility weighted imaging( SWI) in the diagnosis of different types of early prostate cancer. Methods A total of 30 patients with prostate cancer were enrolled in the study group from June 2017 to June 2018. All patients were tested for prostate specific antigen( PSA).According to the range of PSA,they were divided into different groups: group A( n = 9) for 0-4 ng/m L,group B( n = 13)for 4-10 ng/m L and group C( n = 8) for > 10 ng/m L. Another 30 cases of benign prostatic hyperplasia in our hospital during the same period were selected as the control group. All patients underwent magnetic resonance susceptibility weighted imaging( MSWI),and the images were observed and examined. The clinical value of MSWI in the diagnosis of different types of early prostate cancer was analyzed. Results There was no difference in Ve level between the four groups( P > 0. 05);Sus E score,Ktrans and Kep levels in group C were higher than those in group B. The results of group B were higher than those of group A and the results in group A were higher than those in the control group( P < 0. 05). Sus E score was positively correlated with Ktrans and Kep levels in the patients with early prostate cancer( P < 0. 05),but there was no correlation with Ve level( P > 0. 05). Conclusion Magnetic resonance susceptibility weighted imaging has a good diagnostic effect on prostate cancer,for it can effectively differentiate and diagnose different types of early prostate cancer. Therefore it is of great significance for clinical diagnosis and evaluation of treatment effect of prostate cancer.
Ojbective To study the advantages and clinical value of magnetic resonance susceptibility weighted imaging( SWI) in the diagnosis of different types of early prostate cancer. Methods A total of 30 patients with prostate cancer were enrolled in the study group from June 2017 to June 2018. All patients were tested for prostate specific antigen( PSA).According to the range of PSA,they were divided into different groups: group A( n = 9) for 0-4 ng/m L,group B( n = 13)for 4-10 ng/m L and group C( n = 8) for > 10 ng/m L. Another 30 cases of benign prostatic hyperplasia in our hospital during the same period were selected as the control group. All patients underwent magnetic resonance susceptibility weighted imaging( MSWI),and the images were observed and examined. The clinical value of MSWI in the diagnosis of different types of early prostate cancer was analyzed. Results There was no difference in Ve level between the four groups( P > 0. 05);Sus E score,Ktrans and Kep levels in group C were higher than those in group B. The results of group B were higher than those of group A and the results in group A were higher than those in the control group( P < 0. 05). Sus E score was positively correlated with Ktrans and Kep levels in the patients with early prostate cancer( P < 0. 05),but there was no correlation with Ve level( P > 0. 05). Conclusion Magnetic resonance susceptibility weighted imaging has a good diagnostic effect on prostate cancer,for it can effectively differentiate and diagnose different types of early prostate cancer. Therefore it is of great significance for clinical diagnosis and evaluation of treatment effect of prostate cancer.
引文
[1]方俊华,闵祥德,冯朝燕,等.磁共振灌注加权成像定量参数在前列腺外周带前列腺癌鉴别诊断中的价值[J].磁共振成像,2015,6(2):136-140.
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[3]李文,李胜凯,林优,等. 3. 0T磁共振DWI、ADC、MRS联合前列腺特异性抗原诊断前列腺癌效能分析[J].实用医学杂志,2017,33(9):1502-1505.
[4]潘昌远,叶华震,梅淼华,等.磁共振扩散加权成像在老年前列腺癌诊断中的应用价值[J].中国老年学杂志,2016,36(8):1895-1897.
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[6]赖吉安,邹良英,黄绍明,等.血清PSA联合PAP检测提高前列腺癌诊断率的临床意义[J].现代医院,2014,14(10):58-59.
[7]万红燕,毕芸祺,衣岩,等.基于体素内不相干运动的MR扩散加权成像对前列腺癌诊断价值的初步研究[J].磁共振成像,2015,6(6):445-449.
[8]汪维,张青,张冰,等.自由臂经会阴多参数磁共振-超声影像融合引导靶向穿刺诊断前列腺癌的前瞻性研究[J].中华泌尿外科杂志,2018,39(3):192-196.
[9]张志平. 3. 0 T磁共振扩散加权成像及表观扩散系数在老年前列腺癌诊断中的价值[J].中国老年学杂志,2015,35(3):689-691.
[10]王省白,高益萍,黎良山,等.磁共振弥散加权成像与动态增强在早期前列腺癌诊断中的应用分析[J].医学影像学杂志,2015,25(11):1991-1994.
[11]孙海燕,方呈祥,刘艳娥,等.盆腔磁共振T2加权像在老年前列腺癌中的诊断价值[J].中国老年学杂志,2015,35(7):1798-1800.
[12]王鑫,王萱,刘明,等.盆腔多参数磁共振诊断模型在早期前列腺癌诊断中的应用研究[J].中华泌尿外科杂志,2015,36(11):826-831.
[13]刘宝冬,聂丰静,陈霞,等.经直肠超声和磁共振弥散加权成像对前列腺癌诊断价值的对比研究[J].中国超声医学杂志,2017,33(6):551-553.
[14]刘明勇,严永峰,孙致强,等.磁共振弥散加权成像联合经直肠超声定位经直肠前列腺穿刺活检80例诊断分析[J].广东医学,2015,36(13):2073-2075.
[15]陈杰,任永芳,曲源,等.磁共振LAVA动态增强半定量分析对前列腺癌的诊断价值[J].中国CT和MRI杂志,2016,14(1):102-105.
[16]闵祥德,王良,冯朝燕,等.磁敏感成像技术与磁共振动态增强扫描对前列腺癌和前列腺炎鉴别诊断价值的对比分析[J].临床放射学杂志,2016,35(2):233-237.
[17]程丽,徐凯,汪秀玲,等.磁共振弥散加权成像及动态增强在前列腺癌诊断中的临床应用价值[J].实用癌症杂志,2017,32(11):1832-1834.
[2]张志鹏,刘明,陈敏,等.磁共振靶向前列腺穿刺活检对前列腺癌诊断的研究[J].中华泌尿外科杂志,2016,37(3):161-164.
[3]李文,李胜凯,林优,等. 3. 0T磁共振DWI、ADC、MRS联合前列腺特异性抗原诊断前列腺癌效能分析[J].实用医学杂志,2017,33(9):1502-1505.
[4]潘昌远,叶华震,梅淼华,等.磁共振扩散加权成像在老年前列腺癌诊断中的应用价值[J].中国老年学杂志,2016,36(8):1895-1897.
[5]王倩,房俊芳,王滨,等.磁共振扩散张量成像诊断前列腺癌的理论基础[J].磁共振成像,2015,6(1):76-80.
[6]赖吉安,邹良英,黄绍明,等.血清PSA联合PAP检测提高前列腺癌诊断率的临床意义[J].现代医院,2014,14(10):58-59.
[7]万红燕,毕芸祺,衣岩,等.基于体素内不相干运动的MR扩散加权成像对前列腺癌诊断价值的初步研究[J].磁共振成像,2015,6(6):445-449.
[8]汪维,张青,张冰,等.自由臂经会阴多参数磁共振-超声影像融合引导靶向穿刺诊断前列腺癌的前瞻性研究[J].中华泌尿外科杂志,2018,39(3):192-196.
[9]张志平. 3. 0 T磁共振扩散加权成像及表观扩散系数在老年前列腺癌诊断中的价值[J].中国老年学杂志,2015,35(3):689-691.
[10]王省白,高益萍,黎良山,等.磁共振弥散加权成像与动态增强在早期前列腺癌诊断中的应用分析[J].医学影像学杂志,2015,25(11):1991-1994.
[11]孙海燕,方呈祥,刘艳娥,等.盆腔磁共振T2加权像在老年前列腺癌中的诊断价值[J].中国老年学杂志,2015,35(7):1798-1800.
[12]王鑫,王萱,刘明,等.盆腔多参数磁共振诊断模型在早期前列腺癌诊断中的应用研究[J].中华泌尿外科杂志,2015,36(11):826-831.
[13]刘宝冬,聂丰静,陈霞,等.经直肠超声和磁共振弥散加权成像对前列腺癌诊断价值的对比研究[J].中国超声医学杂志,2017,33(6):551-553.
[14]刘明勇,严永峰,孙致强,等.磁共振弥散加权成像联合经直肠超声定位经直肠前列腺穿刺活检80例诊断分析[J].广东医学,2015,36(13):2073-2075.
[15]陈杰,任永芳,曲源,等.磁共振LAVA动态增强半定量分析对前列腺癌的诊断价值[J].中国CT和MRI杂志,2016,14(1):102-105.
[16]闵祥德,王良,冯朝燕,等.磁敏感成像技术与磁共振动态增强扫描对前列腺癌和前列腺炎鉴别诊断价值的对比分析[J].临床放射学杂志,2016,35(2):233-237.
[17]程丽,徐凯,汪秀玲,等.磁共振弥散加权成像及动态增强在前列腺癌诊断中的临床应用价值[J].实用癌症杂志,2017,32(11):1832-1834.