上海市金泽镇成人下肢静脉曲张患病状况及相关因素分析
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摘要
【目的】调查上海市金泽镇成人下肢静脉曲张患病情况及其危险因素。【方法】采用多阶段随机抽样方法,对上海市青浦区金泽镇9个村18岁及以上居民共2 100人进行问卷调查和体格检查,主要涉及静脉曲张患病情况和相关因素,应用logistic回归模型进行患病因素分析。【结果】有效统计问卷共2 048份(女1 069人,男979人),青浦区金泽镇成人静脉曲张患病率为10.5%(216/2 048),其中男性、女性的患病率分别为11.0%(108/979)和10.1%(108/1 069)。多因素logistic回归分析年龄、平均日站立时间、血脂异常、家族遗传病史等变量为下肢静脉曲张患病的主要危险因素。【结论】青浦区金泽镇成人下肢静脉曲张患病率不可忽视;有家族遗传史、血脂异常、体力劳动强度大的人群是下肢静脉疾病预防控制的重点人群。
[Objective] To investigate the morbidity and risk factors of varicose veins(VVs) in adult lower limbs in Jinze Township of Shanghai. [Methods] Multistage random sampling method was employed to include 2 100 local residents aged over 18 years from Jinze Township,who were investigated by questionnaires and physical examination in relation fo prevalence and risk factors of varicose veins in adult lower limbs in Qingpu District of Shanghai. [Results] A total of 2 048 valid questionnaires were collected from 1 069 females and 979 males.The prevalence rate of VVs was 10.5%(216/2 048),11.0%(108/979)in males and 10.1%(108/1 069) in females.It was found that age,average standing time per day,hyperlipidemia and family history of VVs were risk factors in the prevalence of VVs based on the results of multiple logistic regression analysis. [Conclusion] The prevalence of VVs in adult lower limbs in Jinze Township of Qingpu District of Shanghai is at a high level.The investigation indicates that great importance should be attached to those with family history of VVs,hyperlipidemia or working with strenuous manual labor.
[Objective] To investigate the morbidity and risk factors of varicose veins(VVs) in adult lower limbs in Jinze Township of Shanghai. [Methods] Multistage random sampling method was employed to include 2 100 local residents aged over 18 years from Jinze Township,who were investigated by questionnaires and physical examination in relation fo prevalence and risk factors of varicose veins in adult lower limbs in Qingpu District of Shanghai. [Results] A total of 2 048 valid questionnaires were collected from 1 069 females and 979 males.The prevalence rate of VVs was 10.5%(216/2 048),11.0%(108/979)in males and 10.1%(108/1 069) in females.It was found that age,average standing time per day,hyperlipidemia and family history of VVs were risk factors in the prevalence of VVs based on the results of multiple logistic regression analysis. [Conclusion] The prevalence of VVs in adult lower limbs in Jinze Township of Qingpu District of Shanghai is at a high level.The investigation indicates that great importance should be attached to those with family history of VVs,hyperlipidemia or working with strenuous manual labor.
引文
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[6]祝楠波,周密,余灿清,等.中国成年人主要慢性病家族史与个体健康生活方式的关联分析[J].中华流行病学杂志,2018,39(12):1537-1543.
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[11]PIAZZA G.Varicose veins[J].Circulation,2014,130(7):582-587.
[12]ZHANG S,MELANDER S.Varicose veins:diagnosis,management,and treatment[J].J Nurse Pract,2014,10(6):417-424.
[13]PIAZZA G.Cardiology patient page.Varicose veins[J].Circulation,2014,130(7):e59-e61.
[14]JACOBS B N,ANDRASKA E A,OBI A T,et al.Pathophysiology of varicose veins[J].J Vasc Surg Venous Lymphat Disord,2017,5(3):460-467.
[15]BHARATH V,KAHN S R,LAZO-LANGNER A.Genetic polymorphisms of vein wall remodeling in chronic venous disease:a narrative and systematic review[J].Blood,2014,124(8):1242-1250.
[16]LI X,JIANG X Y,GE J,et al.Aberrantly expressed lncRNAs in primary varicose great saphenous veins[J].PLoS One,2014,9(1):e86156.
[17]VAN RIJ A M,De ALWIS C S,JIANG P,et al.Obesity and impaired venous function[J].Eur J Vasc Endovasc Surg,2008,35(6):739-744.
[18]ALBITSKII A V,LAKUNIN K,PETUKHOV V A.The role of hyperlipidemia in the pathogenesis of acute thrombophlebitis of the surface veins of the lower extremities[J].Grud Serdechnososudistaia Khir,1993,(6):53-54.
[2]LI L,LI X,THE E,et al.Low expression of lncRNA-GAS5 is implicated in human primary varicose great saphenous veins[J].PLoS One,2015,10(3):e0120550.
[3]ONIDA S,LANE T R A,DAVIES A H.Varicose veins and their management[J].Surgery (Oxford),2013,31(5):211-217.
[4]黄涛,李立明.系统流行病学[J].中华流行病学杂志,2018,39(5):694-699.
[5]常光其,陈翠菊,陈忠,等.慢性下肢静脉疾病诊断与治疗中国专家共识[J].中国血管外科杂志(电子版),2014,6(3):143-151.
[6]祝楠波,周密,余灿清,等.中国成年人主要慢性病家族史与个体健康生活方式的关联分析[J].中华流行病学杂志,2018,39(12):1537-1543.
[7]中华医学会糖尿病学分会.中国2型糖尿病防治指南(2013年版)[J].中国糖尿病杂志,2014,22(8):2-42.
[8]刘力生.中国高血压防治指南2010[J].中华高血压杂志,2011,19(8):701-743.
[9]武阳丰,赵冬,周北凡,等.中国成人血脂异常诊断和危险分层方案的研究[J].中华心血管病杂志,2007,35(5):428-433.
[10]邱桦,阮晓楠,周先锋,等.上海市浦东新区成人糖尿病患病情况及相关因素分析[J].上海预防医学,2015,27(11):673-677.
[11]PIAZZA G.Varicose veins[J].Circulation,2014,130(7):582-587.
[12]ZHANG S,MELANDER S.Varicose veins:diagnosis,management,and treatment[J].J Nurse Pract,2014,10(6):417-424.
[13]PIAZZA G.Cardiology patient page.Varicose veins[J].Circulation,2014,130(7):e59-e61.
[14]JACOBS B N,ANDRASKA E A,OBI A T,et al.Pathophysiology of varicose veins[J].J Vasc Surg Venous Lymphat Disord,2017,5(3):460-467.
[15]BHARATH V,KAHN S R,LAZO-LANGNER A.Genetic polymorphisms of vein wall remodeling in chronic venous disease:a narrative and systematic review[J].Blood,2014,124(8):1242-1250.
[16]LI X,JIANG X Y,GE J,et al.Aberrantly expressed lncRNAs in primary varicose great saphenous veins[J].PLoS One,2014,9(1):e86156.
[17]VAN RIJ A M,De ALWIS C S,JIANG P,et al.Obesity and impaired venous function[J].Eur J Vasc Endovasc Surg,2008,35(6):739-744.
[18]ALBITSKII A V,LAKUNIN K,PETUKHOV V A.The role of hyperlipidemia in the pathogenesis of acute thrombophlebitis of the surface veins of the lower extremities[J].Grud Serdechnososudistaia Khir,1993,(6):53-54.