空间占位法制备多孔Ti-5Cu合金及性能的研究
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摘要
以钛粉和铜粉为原料,碳酸氢铵为占位剂,应用粉末冶金的方法制备出多孔Ti-5Cu合金,并对其微观结构和力学性能进行表征。结果表明:碳酸氢铵作为占位剂时,其添加量对制备出的多孔Ti-5Cu合金的相组成没有明显影响,但对其孔结构和力学性能有显著影响。当加入的碳酸氢铵量增加时,多孔Ti-5Cu合金的孔隙率随之增加,大孔结构变得相互连通;其弹性模量和抗压强度均降低,可通过调整碳酸氢铵的添加量调整其与自然骨近似匹配,有潜力用作多孔抗菌硬组织植入体。
Porous Ti-5Cu alloy was prepared by powder metallurgy method using titanium powder and copper powder as raw materials and ammonium bicarbonate as space holder agent, and its microstructure and mechanical properties were characterized. The results show that taking ammonium bicarbonate as a space holder, its adding amount has no significant effect on the phase composition of porous Ti-5Cu alloy, but it has a significant effect on its pore structure and mechanical properties. With the increase of the amount of ammonium bicarbonate, the porosity of porous Ti-5Cu alloy increases, the macro-pore structure becomes interconnected; the elastic modulus and compressive strength of porous Ti-5Cu alloy decrease,which could be adjusted to approximately match with that of the natural bone by adjusting the amount of ammonium bicarbonate. It has the potential to be used as porous antibacterial hard tissue implants.
Porous Ti-5Cu alloy was prepared by powder metallurgy method using titanium powder and copper powder as raw materials and ammonium bicarbonate as space holder agent, and its microstructure and mechanical properties were characterized. The results show that taking ammonium bicarbonate as a space holder, its adding amount has no significant effect on the phase composition of porous Ti-5Cu alloy, but it has a significant effect on its pore structure and mechanical properties. With the increase of the amount of ammonium bicarbonate, the porosity of porous Ti-5Cu alloy increases, the macro-pore structure becomes interconnected; the elastic modulus and compressive strength of porous Ti-5Cu alloy decrease,which could be adjusted to approximately match with that of the natural bone by adjusting the amount of ammonium bicarbonate. It has the potential to be used as porous antibacterial hard tissue implants.
引文
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[2]任军帅,张英明,谭江,等.生物医用钛合金材料发展现状及趋势[J].材料导报:纳米与新材料专辑,2016,30(2):384-8.
[3]Kr?ger H, Venesmaa P, Jurvelin J, et al.Bone density at the proximal femur after total hip arthroplasty[J].Clinical Orthopaedics and Related Research,1998,352:66-74.
[4]汤慧萍,王建.多孔钛的研究进展[J].中国材料进展,2014(9):576-585.
[5]Palka K, Pokrowiecki R.Porous titanium implants:a review[J].Advanced Engineering Materials,2018,17:648-652.
[6]Wen C E,Yamada Y,Shimojima K,et al.Processing and mechanical properties of autogenous titanium implant materials[J].Journal of Materials Science:Materials in Medicine,2002,13(4):397-401.
[7]Ryan G, Pandit A, Apatsidis D P.Fabrication methods of porous metals for use in orthopaedic applications[J].Biomaterials,2006,27(13):2651-2670.
[8]Alvarez K, Nakajima H.Metallic scaffolds for bone regeneration[J].Materials,2009,2(3):790-832.
[9]肖健,邱贵宝.泡沫或多孔钛的制备方法研究进展[J].稀有金属材料与工程,2017(6):1734-1748.
[10]Hsu H C, Wu S C, Hsu S K, et al.Effect of ball milling on properties of porous Ti-7.5Mo alloy for biomedical applications[J].Journal of Alloys and Compounds,2014,582(2):793-801.
[11]张力,曹书豪,段可,等.颗粒造孔制备多孔钛中结构及性能影响因素[J].热加工工艺,2013,42(18):84-87.
[12]赵朝勇,张雪峰,张磊,等.多孔Ti-5Ag合金的制备及力学性能研究[J].钢铁钒钛,2018(2):49-55.
[13]赵朝勇,张雪峰,张磊,等.银含量对多孔钛微观结构和力学性能的影响[J].钢铁钒钛,2018(3):40-45.
[14]Zhang E, Li F, Wang H, et al.A new antibacterial titanium-copper sintered alloy:preparation and antibacterial property[J].Materials Science and Engineering C,2013,33(7):4280-4287.
[15]Liu J, Li F, Liu C, et al.Effect of Cu content on the antibacterial activity of titanium-copper sintered alloys[J].Materials Science and Engineering C,2014,35(1):392-400.
[16]Shirai T,Tsuchiya H,Shimizu T,et al.Prevention of pin tract infection with titanium-copper alloys[J].Journal of Biomedical Materials Research Part B Applied Biomaterials,2009,91B(1):373-380.
[17]Zhang E, Zheng L, Liu J, et al.Influence of Cu content on the cell biocompatibility of Ti-Cu sintered alloys[J].Materials Science and Engineering C,2015,46(8):148-157.
[18]袁广银,张佳,丁文江.可降解医用镁基生物材料的研究进展[J].中国材料进展,2011,30(2):44-50.
[19]Karageorgiou V, Kaplan D.Porosity of 3D biomaterial scaffolds and osteogenesis[J].Biomaterials,2005,26(27):5474-5491.
[20]Fujibayashi S, Neo M, Kim H M, et al.Osteoinduction of porous bioactive titanium metal[J].Biomaterials,2004,25(3):443-450.
[21]Takemoto M,Fujibayashi S,Neo M,et al.Osteoinductive porous titanium implants:Effect of sodium removal by dilute HCl treatment[J].Biomaterials,2006,27(13):2682-2691.
[22]Zhao C, Zhu X, Liang K, et al.Osteoinduction of porous titanium:a comparative study between acid-alkali and chemicalthermal treatments[J].Journal of Biomedical Materials Research Part B Applied Biomaterials,2010,95(2):387-396.
[23]唐仁政,田荣璋.二元合金相图及中间相晶体结构[M].湖南:中南大学出版社,2009.
[24]Gibson L J.The mechanical behaviour of cancellous bone[J].Journal of Biomechanics,1985,18(5):317-328.