皮片移植修复联合局部氧疗对深度烧伤患者创面的治疗效果研究
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摘要
目的研究皮片移植修复联合局部氧疗对深度烧伤患者创面的治疗效果。方法选择2013年6月—2018年5月本院收治的267例深度烧伤患者,随机分为两组。两组均采用皮片移植修复治疗,观察组联合采用局部氧疗。比较两组的创面修复效果。结果观察组治疗创面的有效率明显高于对照组(P<0.05);观察组深度烧伤患者创面的愈合时间明显短于对照组(P<0.05);观察组的住院时间、肉芽组织生长时间和疼痛评分均明显低于对照组(P<0.05);观察组的创面愈合率为81.34%(109/134),明显高于对照组的65.41%(87/133)(P<0.05),且观察组的感染发生率和并发症发生率明显低于对照组(P<0.05)。结论皮片移植修复联合局部氧疗有助于促进深度烧伤患者创面的修复,创面愈合率高、愈合时间短且并发症低,值得应用推广。
Objective To discuss the effect of skin graft repair combined with local oxygen therapy on deep burn wounds. Methods 267 cases of deep burn patients from June 2013 to May 2018 were divided into two groups randomly. The two groups were treated with skin graft, and the observation group was treated with local oxygen therapy in addition. The wound healing effects were compared. Results The effective rate of the observation group was significantly higher than control group(P<0.05). The healing time of observation group was significantly shorter than control group(P<0.05), and the hospitalization time, granulation tissue growth time and pain score of observation group were significantly lower than control group(P<0.05). The wound healing rate in the observation group was 81.34%(109/134), which was significantly higher than control group 65.41%(87/133)(P<0.05), and the incidence of infection and complications in the observation group was significantly lower than control group(P<0.05). Conclusion Skin graft repair combined with local oxygen therapy can promote the repair of deep burn wounds. The wound healing rate is high, the healing time is short and the complications are low.
Objective To discuss the effect of skin graft repair combined with local oxygen therapy on deep burn wounds. Methods 267 cases of deep burn patients from June 2013 to May 2018 were divided into two groups randomly. The two groups were treated with skin graft, and the observation group was treated with local oxygen therapy in addition. The wound healing effects were compared. Results The effective rate of the observation group was significantly higher than control group(P<0.05). The healing time of observation group was significantly shorter than control group(P<0.05), and the hospitalization time, granulation tissue growth time and pain score of observation group were significantly lower than control group(P<0.05). The wound healing rate in the observation group was 81.34%(109/134), which was significantly higher than control group 65.41%(87/133)(P<0.05), and the incidence of infection and complications in the observation group was significantly lower than control group(P<0.05). Conclusion Skin graft repair combined with local oxygen therapy can promote the repair of deep burn wounds. The wound healing rate is high, the healing time is short and the complications are low.
引文
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[9] 张志云,徐姝娟,王方,等.负压封闭引流技术联合局部氧疗在重度压疮治疗中的应用[J].皖南医学院学报,2017,36(5):504-506.
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[13] 冷冬,王建章,宋保强.烧伤创面内Notch信号因子变化临床研究[J].临床军医杂志,2017,45(4):360-362.
[14] 王欣,李晓庆,马诗雨,等.脐带间充质干细胞与烧伤创面愈合[J].实用医学杂志,2017,33(18):3148-3150.
[15] 孙家驹,贺兴,谢晓平.聚维酮碘膏联合湿润烧伤膏治疗四肢Ⅱ度烧伤创面的效果观察[J].中国现代医学杂志,2017,27(20):82-85.
[16] 彭杨,覃岭,秦花,等.局部给氧、负压引流促进Ⅱ度烧伤创面愈合效果观察[J].山东医药,2016,56(12):59-60.
[2] 潘南芳,卓金,王欣.异种脱细胞真皮基质移植修复深度烧伤创面[J].中国组织工程研究,2016,20(3):408-412.
[3] 牟晓欣,牟军,解晶.负压封闭引流联合游离植皮对深度烧伤感染创面的疗效研究[J].中华医院感染学杂志,2017,27(9):2084-2087.
[4] 庞淑光,叶胜捷,叶鹂柳,等.MEEK微型皮片移植在大面积深度烧伤创面的应用体会[J].创伤外科杂志,2016,18(4):236-238.
[5] 岳丽青,王晓燕,彭欢,等.康复路径对深度烧伤手术后康复效果的影响[J].中国现代医学杂志,2016,26(7):126-132.
[6] 李廷,王晨,程大胜,等.人工真皮支架早期修复特重烧伤手足深度创面[J].第二军医大学学报,2016,37(1):1-4.
[7] 刘洋,张宜澜,黄亚兰,等.人工真皮联合碱性成纤维细胞生长因子在瘢痕和皮肤深度创面整复中的临床应用[J].中华烧伤杂志,2016,32(4):198-203.
[8] 蒋琪霞,徐娟,李晓华,等.负压封闭结合局部氧疗改善创伤性慢性伤口愈合的效果研究[J].医学研究生学报,2016,29(7):731-736.
[9] 张志云,徐姝娟,王方,等.负压封闭引流技术联合局部氧疗在重度压疮治疗中的应用[J].皖南医学院学报,2017,36(5):504-506.
[10] Chiang I H,Chen S G,Huang K L,et al.Adjunctive hyperbaric oxygen therapy in severe burns:Experience in Taiwan Formosa Water Park dust explosion disaster[J].Burns J Inter Soci Burn Injuries,2016,43(4):S03054-S03056.
[11] Culnan DM,Craft-coffman B,Bitz GH,et al.Carbon monoxide and cyanide poisoning in the burned pregnant patient:an indication for hyperbaric oxygen therapy[J].An Plastic Surgery,2018,80(2):S106-S112.
[12] 王国才,程秀萍,杨涛.深度烧伤创面愈后的康复治疗[J].中国医刊,2017,52(12):8-9.
[13] 冷冬,王建章,宋保强.烧伤创面内Notch信号因子变化临床研究[J].临床军医杂志,2017,45(4):360-362.
[14] 王欣,李晓庆,马诗雨,等.脐带间充质干细胞与烧伤创面愈合[J].实用医学杂志,2017,33(18):3148-3150.
[15] 孙家驹,贺兴,谢晓平.聚维酮碘膏联合湿润烧伤膏治疗四肢Ⅱ度烧伤创面的效果观察[J].中国现代医学杂志,2017,27(20):82-85.
[16] 彭杨,覃岭,秦花,等.局部给氧、负压引流促进Ⅱ度烧伤创面愈合效果观察[J].山东医药,2016,56(12):59-60.