麻杏石甘汤合千金苇茎汤加减治疗社区获得性肺炎47例临床疗效观察
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摘要
目的:探讨麻杏石甘汤合千金苇茎汤加减治疗对社区获得性肺炎患者炎症指标以及中医证候积分的影响。方法:回顾性分析2017年1月—2018年10月期间在我院治疗的94例社区获得性肺炎患者的临床资料,依据上述入选者治疗方案的不同,将其分为对照组(哌拉西林他唑巴坦钠注射液治疗,47例)与观察组(哌拉西林他唑巴坦钠注射液+麻杏石甘汤合千金苇茎汤加减治疗,47例),分别于治疗前与治疗后比较两组患者炎性指标[C反应蛋白(C-reactive protein,CRP)与降钙素原(Procalcitonin,PCT)]与中医证候积分。结果:治疗前,两组患者CRP与PCT水平对比,差异无统计学意义(P>0.05);治疗10d后,观察组患者CRP与PCT水平均低于对照组患者,差异有统计学意义(P<0.05);治疗前,两组患者中医证候积分对比,差异无统计学意义(P>0.05);治疗第3d与治疗第10d,观察组中医证候积分均低于对照组,差异有统计学意义(P<0.05)。结论:社区获得性肺炎患者经麻杏石甘汤合千金苇茎汤加减治疗,可有效缓解临床症状,利于控制炎症反应,促使患者早日康复。
Objective:To investigate the effect of Maxing Shigan decoction and Qianjin Weibei decoction on in?ammatory index and TCM syndrome score of community-acquired pneumonia patients. Methods: The clinical data of 94 patients with community acquired pneumonia treated in our hospital from January 2017 to October 2018 were analyzed retrospectively. They were divided into two groups: the control group(piperacillin tazobactam sodium injection, 47 cases)and the observation group(piperacillin tazobactam sodium injection maxing Shigan decoction combined with Qianjin Weicai decoction, 47 cases), and the other 47 cases were treated with piperacillin tazobactam sodium injection. In?ammation index, such as C-reactive protein(C-reactive protein, CRP), procalcitonin(Procalcitonin,PCT)] and TCM syndrome integral before and after treatment were compared. Results: There was no signi?cant difference in the levels of CRP and PCT between the two groups before treatment(P>0.05.After 10 days of treatment, the levels of CRP and PCT in the observation group were lower than those in the control group(P<0.05). Before treatment, there was no signi?cant difference in the scores of TCM syndromes between the two groups(P>0.05), and there was no signi?cant difference between the two groups on the 3 rd day and the 10 th day(P>0.05). The scores of TCM syndromes in the observation group were lower than those in the control group(P<0.05). Conclusion: The treatment of community acquired pneumonia with Maxing Shigan decoction and Qianjin Weibei decoction can effectively relieve the clinical symptoms, control the in?ammatory reaction and promote the patients to recover as soon as possible.
Objective:To investigate the effect of Maxing Shigan decoction and Qianjin Weibei decoction on in?ammatory index and TCM syndrome score of community-acquired pneumonia patients. Methods: The clinical data of 94 patients with community acquired pneumonia treated in our hospital from January 2017 to October 2018 were analyzed retrospectively. They were divided into two groups: the control group(piperacillin tazobactam sodium injection, 47 cases)and the observation group(piperacillin tazobactam sodium injection maxing Shigan decoction combined with Qianjin Weicai decoction, 47 cases), and the other 47 cases were treated with piperacillin tazobactam sodium injection. In?ammation index, such as C-reactive protein(C-reactive protein, CRP), procalcitonin(Procalcitonin,PCT)] and TCM syndrome integral before and after treatment were compared. Results: There was no signi?cant difference in the levels of CRP and PCT between the two groups before treatment(P>0.05.After 10 days of treatment, the levels of CRP and PCT in the observation group were lower than those in the control group(P<0.05). Before treatment, there was no signi?cant difference in the scores of TCM syndromes between the two groups(P>0.05), and there was no signi?cant difference between the two groups on the 3 rd day and the 10 th day(P>0.05). The scores of TCM syndromes in the observation group were lower than those in the control group(P<0.05). Conclusion: The treatment of community acquired pneumonia with Maxing Shigan decoction and Qianjin Weibei decoction can effectively relieve the clinical symptoms, control the in?ammatory reaction and promote the patients to recover as soon as possible.
引文
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[9]戴乐凤.香砂六君子汤加味联合穴位拔罐治疗老年肺脾气虚型社区获得性肺炎40例[J].浙江中医杂志, 2018, 53(05):338.
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[11]魏毅,许先荣.清金益气汤治疗气阴两虚型社区获得性肺炎40例观察[J].浙江中医杂志, 2018, 53(07):496.
[12]程玉峰,何蕊,魏姗姗,等.麻杏石甘汤合千金苇茎汤加减治疗风温肺热病痰热壅肺证35例[J].河南中医, 2017, 37(01):102-104.
[2]曾小云,李慧,胡春林,等.老年人反复发生社区获得性肺炎的临床特征和危险因素分析[J].中华全科医师杂志, 2016, 15(06):434-438.
[3]徐国亮.麻杏石甘汤合千金苇茎汤加味治疗重症肺炎疗效观察[J].中国中医急症, 2016, 25(09):1805-1806.
[4]中华医学会呼吸病学分会.中国成人社区获得性肺炎诊断和治疗指南(2016年版)[J].中华结核和呼吸杂志, 2016, 39(04):253-279.
[5]国家中医药管理局.中医病症诊断疗效标准[S].南京:南京大学出版社,1994:10-11.
[6]李音,姜红妮,瞿介明.老年、高龄老年和超高龄老年社区获得性肺炎的临床特征及预后对照分析[J].老年医学与保健, 2016, 22(01):19-23.
[7]陈亮,李真.老年重症社区获得性肺炎临床特征及预后影响因素分析[J].国际流行病学传染病学杂志, 2015, 42(06):380-383.
[8]苏庆珠,孙兴华,杨艳华,等.中西医结合治疗社区获得性肺炎痰热壅肺证临床研究[J].中医学报, 2016, 31(12):1855-1858.
[9]戴乐凤.香砂六君子汤加味联合穴位拔罐治疗老年肺脾气虚型社区获得性肺炎40例[J].浙江中医杂志, 2018, 53(05):338.
[10]邹鹏,蔡海荣,袁康,等.社区获得性肺炎中医证型与炎症指标的相关性研究[J].中国中医急症, 2018, 27(11):1999-2001.
[11]魏毅,许先荣.清金益气汤治疗气阴两虚型社区获得性肺炎40例观察[J].浙江中医杂志, 2018, 53(07):496.
[12]程玉峰,何蕊,魏姗姗,等.麻杏石甘汤合千金苇茎汤加减治疗风温肺热病痰热壅肺证35例[J].河南中医, 2017, 37(01):102-104.