肝胃百合汤联合西药治疗幽门螺杆菌阳性消化性溃疡肝郁气滞证的临床观察
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摘要
[目的]观察肝胃百合汤联合西药治疗幽门螺杆菌(Hp)阳性消化性溃疡肝郁气滞证的临床疗效。[方法]选取Hp阳性消化性溃疡肝郁气滞证患者60例,采取随机数字表法分为2组,每组各30例。2组均予根除Hp治疗,观察组加予肝胃百合汤,对照组加予胃苏颗粒。治疗时间均为4周。比较2组患者治疗前后中医症候总积分、临床疗效及Hp根除率。[结果]2组治疗后中医症候总积分均明显下降(P<0.05),且观察组低于对照组(P<0.05);治疗后2组总体有效率分别为90.00%和76.67%,观察组优于对照组(P<0.05);治疗后2组Hp根除率分别为86.67%和73.33%,观察组优于对照组(P<0.05)。[结论]肝胃百合汤联合西药治疗Hp阳性消化性溃疡肝郁气滞证的临床疗效明显。
[Objective]To observe the clinical efficacy of Ganwei Baihe decoction combined with western medicine in the treatment of Hp positive peptic ulcer with liver Qi stagnation syndrome.[Methods]60cases of Hp-positive peptic ulcer with stagnation of Liver-Qi were selected and randomly divided into two groups with 30 cases in each group adopting number table method.Both groups were treated with Hp eradication,while the observation group was given Ganwei Baihe decoction,and the control group was given Weisu granules.The treatment time was 4weeks.The TCM syndrome total score,clinical efficacy and Hp eradication rate of the 2groups before and after treatment were compared.[Results]The total scores of TCM syndromes in the two groups were significantly decreased(P<0.05),and the observation group was lower than that of control group(P<0.05).The overall effective rate of the two groups after treatment was90.00%and 76.67%,respectively.The control group was better than the control group(P<0.05);the Hp eradication rate of the two groups after treatment was 86.67%and 73.33%,respectively,and the observation group was superior to the control group(P<0.05).[Conclusion]The clinical efficacy of Ganwei Baihe decoction combined with western medicine in the treatment of Hp-positive peptic ulcer with liver Qi stagnation syndrome is obvious.
[Objective]To observe the clinical efficacy of Ganwei Baihe decoction combined with western medicine in the treatment of Hp positive peptic ulcer with liver Qi stagnation syndrome.[Methods]60cases of Hp-positive peptic ulcer with stagnation of Liver-Qi were selected and randomly divided into two groups with 30 cases in each group adopting number table method.Both groups were treated with Hp eradication,while the observation group was given Ganwei Baihe decoction,and the control group was given Weisu granules.The treatment time was 4weeks.The TCM syndrome total score,clinical efficacy and Hp eradication rate of the 2groups before and after treatment were compared.[Results]The total scores of TCM syndromes in the two groups were significantly decreased(P<0.05),and the observation group was lower than that of control group(P<0.05).The overall effective rate of the two groups after treatment was90.00%and 76.67%,respectively.The control group was better than the control group(P<0.05);the Hp eradication rate of the two groups after treatment was 86.67%and 73.33%,respectively,and the observation group was superior to the control group(P<0.05).[Conclusion]The clinical efficacy of Ganwei Baihe decoction combined with western medicine in the treatment of Hp-positive peptic ulcer with liver Qi stagnation syndrome is obvious.
引文
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[9]浦清,彭明发,方菁.三联疗法联合疏肝理气活血方治疗幽门螺杆菌阳性消化性溃疡患者的疗效观察[J].中国中西医结合消化杂志,2016,24(9):709-711.
[10]王大鹏,俞静,张俊.柴胡舒肝散联合西药四联疗法治疗老年消化性溃疡的疗效及对患者生长因子表达的影响[J].中国中西医结合消化杂志,2017,25(7):553-556.
[11]张娜,朱莹.朱莹运用肝胃百合汤化裁治疗胃痛验案3则[J].湖南杂志,2017,33(5):106-107.
[2]刘亚祥,李煜国.疏肝和胃法配合奥美拉唑治疗肝气犯胃型消化性溃疡的临床研究[J].现代中西医结合杂志,2016,25(28):3165-3167.
[3]杨瑞玲.奥美拉唑联合甲硝唑等三联方案治疗消化性溃疡[J].临床医学,2009,29(3):71-72.
[4]瞿艳红.埃索美拉唑治疗消化性溃疡的临床观察[J].临床合理用药杂志,2012,5(29):65-65.
[5]郭金秀.中西医结合治疗消化性溃疡研究进展[J].中国中医急症,2010,19(3):495-496.
[6]张万岱,李军祥,陈治水,等.消化性溃疡中西医结合诊疗共识意见(2011·天津)[J].现代消化及介入诊疗,2012,17(3):177-180.
[7]中国中西医结合学会消化系统疾病专业委员会.消化性溃疡中西医结合诊疗共识意见(2017年)[J].中国中西医结合消化杂志,2018,26(2):112-120.
[8]刘亚祥,李煜国.疏肝和胃法配合奥美拉唑治疗肝气犯胃型消化性溃疡的临床研究[J].现代中西医结合杂志,2016,25(28):3165-3167.
[9]浦清,彭明发,方菁.三联疗法联合疏肝理气活血方治疗幽门螺杆菌阳性消化性溃疡患者的疗效观察[J].中国中西医结合消化杂志,2016,24(9):709-711.
[10]王大鹏,俞静,张俊.柴胡舒肝散联合西药四联疗法治疗老年消化性溃疡的疗效及对患者生长因子表达的影响[J].中国中西医结合消化杂志,2017,25(7):553-556.
[11]张娜,朱莹.朱莹运用肝胃百合汤化裁治疗胃痛验案3则[J].湖南杂志,2017,33(5):106-107.