色素性痒疹1例
摘要
报告1例色素性痒疹。患者女,18岁,上肢、胸前、腰背部皮疹伴瘙痒4年。皮肤专科检查:腰背部、上肢、胸前部可见片状暗褐色色素沉着斑,相互融合成网状,其间及边缘可见少许散在淡红色丘疹、丘疱疹,无明显鳞屑,无毛细血管扩张。腰背部皮损组织病理示:表皮轻度增生,棘细胞间轻度水肿,基底细胞灶区空泡化变性,真皮浅层血管周围淋巴细胞及中性粒细胞为主浸润,并见噬黑素细胞及色素颗粒。根据临床特征及病理检查,诊断:色素性痒疹。治疗:予盐酸多西环素肠溶胶囊100 mg,每日2次口服,治疗一周后患者觉瘙痒减轻,原红色皮疹转暗红色。后继续给予多西环素口服2周,每次100 mg,每日2次。患者最后失访。
引文
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[6] TORRELO A, AZORN D, NOGUERA L,et al.Segmental prurigo pigmentosa[J].Pediatr Dermatol,2014,31(4):523-525.
[7] JANG M S,BAEK J W,KANG D Y,et al.Successful treatment with narrowband UVB phototherapy in prurigo pigmentosa associated with pregnancy[J].Eur J Dermatol,2011,21(4):634-635.
[8] 赵莉.色素性痒疹1例[J].中国皮肤[9] 蔡林,杜鹃,张建中.暂时性棘层松解性皮病[J].临床皮肤科杂志,2007,36(2):121-122.性病学杂志,2014,28(12):1275-1276.
[10] 储开宇,钟卫红,莫惠芳,等.色素性痒疹1例[J].皮肤性病诊疗学杂志,2017,24(4):285-287.
[11] 柳岩,张剑,邓永琼,等.血管萎缩性皮肤异色病1例[J].中国麻风皮肤病杂志,2014,30(6):371-373.
[12] 姜彬,陈办成,于波,等.色素性痒疹1例[J].皮肤性病诊疗学杂志,2017,24(2):124-126.
[13] AKOGLU G,BOZTEPE G,KARADUMAN A.Prurigo pigmentosa successfully treated with low-dose isotretinoin[J].Dermatology,2006,213(4):331-333.
[2] KIM T I, CHOI J W, JEONG K H, et al. Pustular prurigo pigmentosa treated with doxycycline[J].J Dermatol,2016,43(8):965-966.
[3] YAMADA D,FUJIKAWA T.Prurigo pigmentosa[J].Am J Med,2017,131(1):e11-e12.
[4] ZENG X, LI L, CUI B N.Prurigo pigmentosa: a clinical and histopathological study of nine Chinese cases[J].J Eur Acad Dermatol Venereol,2016,30(10):1794-1798.
[5] SATTER E, ROZELLE C, SPERLING L.Prurigo Pigmentosa:an under-recognized inflammatory dermatosis characterized by an evolution of distinctive clinicopathological features[J].J Cutan Pathol,2016,43(10):809-814.
[6] TORRELO A, AZORN D, NOGUERA L,et al.Segmental prurigo pigmentosa[J].Pediatr Dermatol,2014,31(4):523-525.
[7] JANG M S,BAEK J W,KANG D Y,et al.Successful treatment with narrowband UVB phototherapy in prurigo pigmentosa associated with pregnancy[J].Eur J Dermatol,2011,21(4):634-635.
[8] 赵莉.色素性痒疹1例[J].中国皮肤[9] 蔡林,杜鹃,张建中.暂时性棘层松解性皮病[J].临床皮肤科杂志,2007,36(2):121-122.性病学杂志,2014,28(12):1275-1276.
[10] 储开宇,钟卫红,莫惠芳,等.色素性痒疹1例[J].皮肤性病诊疗学杂志,2017,24(4):285-287.
[11] 柳岩,张剑,邓永琼,等.血管萎缩性皮肤异色病1例[J].中国麻风皮肤病杂志,2014,30(6):371-373.
[12] 姜彬,陈办成,于波,等.色素性痒疹1例[J].皮肤性病诊疗学杂志,2017,24(2):124-126.
[13] AKOGLU G,BOZTEPE G,KARADUMAN A.Prurigo pigmentosa successfully treated with low-dose isotretinoin[J].Dermatology,2006,213(4):331-333.