再生丝素蛋白可纺性研究
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摘要
静电纺丝技术制备的纳米纤维具有极高的比表面积和孔隙率等独特性质,使其在生物医学、电子、能源等方面具有广泛的应用前景。丝素蛋白由于其独特的机械性能、生物相容性和缓慢的降解性,成为组织工程的基质材料。利用静电纺丝技术进行了再生丝素蛋白的可纺性研究,获得了相应的静电纺丝工艺参数,取得了预期的效果。
The nano-fibers prepared by electrostatic spinning technology have high specific surface area, high porosity and other unique properties, which make them have wide application prospects in biomedicine, electronics, energy and other fields. Silk fibroin has become a matrix material for tissue engineering due to its unique mechanical properties, biocompatibility and slow degradation. In this paper, the spinnability of regenerated silk fibroin was studied by using electrostatic spinning technology, the process parameters of electrostatic spinning were obtained and the expected results were obtained.
The nano-fibers prepared by electrostatic spinning technology have high specific surface area, high porosity and other unique properties, which make them have wide application prospects in biomedicine, electronics, energy and other fields. Silk fibroin has become a matrix material for tissue engineering due to its unique mechanical properties, biocompatibility and slow degradation. In this paper, the spinnability of regenerated silk fibroin was studied by using electrostatic spinning technology, the process parameters of electrostatic spinning were obtained and the expected results were obtained.
引文
[1]刘力菲,李伟,黄潇楠.静电纺丝纳米纤维的制备与应用[J].首都师范大学学报:自然科学版,2017,38(1):58-63.
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[5]VALIZADEH A,FAR K HANI S M.Elect rospin ning and electrospun nanofibres[J].Iet Nanobiotechnology,2014,8(2):83-92.
[6]KIM I G,LEE J H,UNNITHAN A R,et al.A comprehensive electricfield analysis of cylinder-typemulti-nozzle electrospinning system for mass production of nanofibers[J].Industrial&Engineering Chemistry,2016(31):251-256.
[7]孙斌,郭勤,王围.静电纺丝生产纳米纤维方法的研究进展[J].化工管理,2018(2):145-147.
[8]赵亚红,牛长梅,龚佳欢,等.静电纺丝石墨烯/丝素蛋白纳米膜的构建及体外生物相容性研究[J].中国修复重建外科杂志,2017(9):1 119-1 126.
[9]王利君,熊杰,骆菁菁,等.聚乳酸-聚己内酯/丝素蛋白三元复合纳米纤维膜支架的结构与性能[J].纺织学报,2017(5):8-13.
[10]朱彩红,石培峰,吕张飞,等.静电纺丝纳米纤维的制备研究[J].无线互联科技,2018,15(5):102-103.
[2]唐培朵,戴俊,杨晓东,等.静电纺丝素纳米纤维在生物医学组织工程领域的研究进展[J].山西化工,2018,175(3):36-39.
[3]LIU M,DUAN X P,LI Y M,et al.Electrospun nanofibers for wound healing[J].Materials Science&Engineering C Materials for Biological Applications,2017(76):1 413-1 423.
[4]LING S J,QIN Z,LI C M,et al.Polymorphic regenerated silk fibers assembled through bioinspired spinning[J].Nature Communications,2017(8):1 387.
[5]VALIZADEH A,FAR K HANI S M.Elect rospin ning and electrospun nanofibres[J].Iet Nanobiotechnology,2014,8(2):83-92.
[6]KIM I G,LEE J H,UNNITHAN A R,et al.A comprehensive electricfield analysis of cylinder-typemulti-nozzle electrospinning system for mass production of nanofibers[J].Industrial&Engineering Chemistry,2016(31):251-256.
[7]孙斌,郭勤,王围.静电纺丝生产纳米纤维方法的研究进展[J].化工管理,2018(2):145-147.
[8]赵亚红,牛长梅,龚佳欢,等.静电纺丝石墨烯/丝素蛋白纳米膜的构建及体外生物相容性研究[J].中国修复重建外科杂志,2017(9):1 119-1 126.
[9]王利君,熊杰,骆菁菁,等.聚乳酸-聚己内酯/丝素蛋白三元复合纳米纤维膜支架的结构与性能[J].纺织学报,2017(5):8-13.
[10]朱彩红,石培峰,吕张飞,等.静电纺丝纳米纤维的制备研究[J].无线互联科技,2018,15(5):102-103.