张晓甦应用补肾化瘀清利法改善子宫内膜容受性
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摘要
胚胎质量和子宫内膜容受性均可影响妊娠结局,有研究表明,子宫内膜容受性低下占胚胎种植率低下的2/3,因此改善子宫内膜容受性对提高妊娠结局至关重要。张晓甦教授总结临床经验认为,子宫内膜容受性低下患者多以湿热瘀结为标,肾虚为致病之本。张师在临床中活用化瘀清利法并结合补肾调周促进内膜充分由增生向分泌期转化,改善子宫内膜容受性,提高胚胎着床几率。
Both embryo quality and endometrial receptivity can af fect pregnancy outcomes. Studies have shown that endometrial receptivity accounts for 2/3 of the low rate of embryo implantation, so improving endometrial receptivity is essential for improving pregnancy outcomes. Professor Zhang Xiaosu summed up the clinical experience that most patients with low endometrial resilience take damp-heat stagnation as the magnification and kidney deficiency as the root causes of the disease. In clinical, Professor Zhang uses the method of clearing and removing blood stasis combined with tonifying kidney and regulating menstrual cycle to promote the transformation of endometrium from hyperplasia to secretory phase, improve endometrial receptivity and increase the probability of embryo implantation.
Both embryo quality and endometrial receptivity can af fect pregnancy outcomes. Studies have shown that endometrial receptivity accounts for 2/3 of the low rate of embryo implantation, so improving endometrial receptivity is essential for improving pregnancy outcomes. Professor Zhang Xiaosu summed up the clinical experience that most patients with low endometrial resilience take damp-heat stagnation as the magnification and kidney deficiency as the root causes of the disease. In clinical, Professor Zhang uses the method of clearing and removing blood stasis combined with tonifying kidney and regulating menstrual cycle to promote the transformation of endometrium from hyperplasia to secretory phase, improve endometrial receptivity and increase the probability of embryo implantation.
引文
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[2]CASPER R F,YANUSHPOLSKY,ELENA H.Optimal endometrial preparation for frozen embryo transfer cycles window of implantation and progesterone support[J].Fertil Steril,2016,105(4):867-872.
[3]SRIVASTAVA A,SENGUPTA J,KRIPLANI A,et al.Profiles of cytokines secreted by isolated human endometrial cells under the influ-ence of chorionic gonadotropin during the window of embryo implantation[J].Reprod Biol Endocrinol,2013,11(1):116.
[4]李华,李蓉,刘洋,等.芬吗通改善反复胚胎移植失败患者子宫内膜血流和提高妊娠率的研究[J].生殖医学杂志,2014,23(1):37-41.
[5]刘菊红,李坚.子宫内膜容受性影响因素的研究进展[J].中国妇产科临床杂志,2018,19(4):369-371.
[6]魏苹,张宜群,赵珊琼.中医药治疗子宫内膜容受性研究进展[J].新中医,2018,50(9):25-28.
[7]傅山.傅青主男女科[M].北京:中国中医药出版社,199342.
[8]封海容,杜伯涛,李洋.影响子宫内膜容受性因素分析[J].中国优生与遗传杂志,2018,26(3):123-125,81.
[9]宋乃光.刘完素医学全书[M].北京:中国中医药出版社,2006:154.
[10]张云.宫腔黏连证候证素特点分析及活血化瘀方的防治作用研究[D].北京:北京中医药大学,2018.
[11]陶小军,闫宇辉,徐志立,等.薏苡仁油抗炎消肿作用研究[J].辽宁中医药大学学报,2015,17(1):45-46.
[12]夏桂成.中医妇科理论与实践[M].北京:人民卫生出版社,2003:395.
[13]傅山.傅青主女科歌括[M].北京:中国中医药出版社,1992:46.
[14]胡秋兰,陈思达,王丽伟,等.针灸改善子宫内膜容受性的研究进展[J].中医药临床杂志,2017,29(3):411-413.