香葛茯茶主要药效学研究
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摘要
目的:对香葛茯茶的主要药效学进行研究。方法:通过观察香葛茯茶对自由饮食实验小鼠体质量、摄食量以及食物利用率方面的影响研究其促消化功效;通过观察香葛茯茶对实验小鼠脾指数和胸腺指数的影响研究其对免疫功能的调节作用;通过观察香葛茯茶对实验大鼠排便情况的影响研究其促排便的功效;通过观察香葛茯茶对自发性高血压大鼠(SHR)模型收缩压的影响研究其对血压的调节作用。结果:香葛茯茶能够显著降低自由饮食小鼠的体质量和食物利用率,与空白对照组比较,差异有统计学意义(P <0. 05或P <0. 01);香葛茯茶能增加小鼠胸腺指数与脾指数,与空白对照组比较,差异有统计学意义(P <0. 05);香葛茯茶在给药4周后能够略微降低SHR尾动脉收缩压(SP),与模型对照组比较,差异有统计学意义(P <0. 05)。结论:香葛茯茶具有减肥、增强免疫、促消化的作用,长期饮用还具有调节血压的功效。
Objective: To investigate the pharmacodynamics of Xianggefu tea. Methods: The effect of Xianggefu tea on body weight,food intake,and food utilization rate was observed in mice with free diet to evaluate the function of Xianggefu tea in promoting digestion. The effect of Xianggefu tea on spleen index and thymus index was observed in experimental mice to evaluate the function of Xianggefu tea in regulating immune function. The effect of Xianggefu tea on defecation was observed in experimental rats to evaluate the function of Xianggefu tea in promoting defecation. The effect of Xianggefu tea on systolic pressure was observed in spontaneously hypertensive rat( SHR) to evaluate the function of Xianggefu tea in regulating blood pressure. Results: Compared with the blank control group,the Xianggefu tea group had significant reductions in body weight and food utilization rate of mice with free diet( P < 0. 05 or P < 0. 01),significant increases in thymus index and spleen index of mice( P < 0. 05),and a significant reduction in systolic pressure of the caudal artery in SHR after 4 weeks of administration( P < 0. 05). Conclusion: Xianggefu tea can reduce body weight,enhance immunity,and promote digestion,and long-term drinking can help to regulate blood pressure.
Objective: To investigate the pharmacodynamics of Xianggefu tea. Methods: The effect of Xianggefu tea on body weight,food intake,and food utilization rate was observed in mice with free diet to evaluate the function of Xianggefu tea in promoting digestion. The effect of Xianggefu tea on spleen index and thymus index was observed in experimental mice to evaluate the function of Xianggefu tea in regulating immune function. The effect of Xianggefu tea on defecation was observed in experimental rats to evaluate the function of Xianggefu tea in promoting defecation. The effect of Xianggefu tea on systolic pressure was observed in spontaneously hypertensive rat( SHR) to evaluate the function of Xianggefu tea in regulating blood pressure. Results: Compared with the blank control group,the Xianggefu tea group had significant reductions in body weight and food utilization rate of mice with free diet( P < 0. 05 or P < 0. 01),significant increases in thymus index and spleen index of mice( P < 0. 05),and a significant reduction in systolic pressure of the caudal artery in SHR after 4 weeks of administration( P < 0. 05). Conclusion: Xianggefu tea can reduce body weight,enhance immunity,and promote digestion,and long-term drinking can help to regulate blood pressure.
引文
[1]梁艳.茯茶的化学成分和保健功能的研究进展[J].蚕桑茶叶通讯,2011(5):29-31.
[2]陈文杰.葛根研究进展[J].中国中医药现代远程教育,2009,7(1):6-8.
[3]袁郝郝.预防人类肥胖的重要性——关于肥胖是糖尿病和心血管疾病重要危险因素的研究[J].特别健康(下),2014(7):709-710.
[4]刘程程. c Tn I、BNP及入院时收缩压水平在急性心衰监测中的意义及其对判断预后的价值[D].长春:吉林大学,2011.
[2]陈文杰.葛根研究进展[J].中国中医药现代远程教育,2009,7(1):6-8.
[3]袁郝郝.预防人类肥胖的重要性——关于肥胖是糖尿病和心血管疾病重要危险因素的研究[J].特别健康(下),2014(7):709-710.
[4]刘程程. c Tn I、BNP及入院时收缩压水平在急性心衰监测中的意义及其对判断预后的价值[D].长春:吉林大学,2011.