151例喉癌患者的中医证型聚类分析
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摘要
目的:探讨喉癌中医证候分布及演变规律,为进一步研究该病的中医药治疗提供依据。方法:编写信息采集表对本单位已出院的喉癌患者进行信息采集,对所得数据进行聚类分析。结果:根据聚类分析得到喉癌的三个证候分类。结论:喉癌的中医证型可能是一个以痰瘀为主导,并逐步演变的过程,随着发病时间的推移、肿瘤的侵犯,痰热瘀互结证所占比例越高,所包含的中医证候要素越多,中医证型越复杂。
Objective: To explore the syndrome distribution principle of laryngeal cancer and the methodology in traditional chinese medicine in order to provide evidence for further study of the etiology,pathogen and syndrome characteristic of this disease.Methods: Totally 151 patients with laryngeal cancer were studied according to the self-compiled symptom questionnaire. And the data was analyzed through cluster analysis. Results: Three syndrome types of laryngeal cancer were identified through cluster analysis according to study results. Conclusion: Development relationship between TCM syndrome type of throat cancer are as follows:with elements of traditional Chinese medicine phlegm and blood stasis as the leading factor and syndrome types will be gradually developed as time migration and tumor invasion.
Objective: To explore the syndrome distribution principle of laryngeal cancer and the methodology in traditional chinese medicine in order to provide evidence for further study of the etiology,pathogen and syndrome characteristic of this disease.Methods: Totally 151 patients with laryngeal cancer were studied according to the self-compiled symptom questionnaire. And the data was analyzed through cluster analysis. Results: Three syndrome types of laryngeal cancer were identified through cluster analysis according to study results. Conclusion: Development relationship between TCM syndrome type of throat cancer are as follows:with elements of traditional Chinese medicine phlegm and blood stasis as the leading factor and syndrome types will be gradually developed as time migration and tumor invasion.
引文
[1]黄选兆,汪吉宝,孔维佳,主编.实用耳鼻咽喉科学[M]. 2版.北京:人民卫生出版社,2008:488.
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[3]Jaseviciene L,Gurevicius R,Obelenis V,et al. Trends in laryngeal cancer incidence in Lithuania:a future perspective[J]. Int J Occup Med Environ Health,2004,17(4):473-477.
[4]卢善婷,魏矿荣,余炳辉,等.中山市1970年-1999年喉癌发病趋势分析[J].现代肿瘤医学,2004,12(2):158-160.
[5]Ferlay J,Bray F,Pisani P,et al. Globocan 2000:cancer incidence,mortality and prevalence worldwide[M]. Lyon:IARC press,2001:5.
[6]Hoffman HT,Porter K,Karnell LH,et al. Laryngeal cancer in the United States:changes in demographics,patterns of care,and survival[J].Laryngoscope,2006,116(9 Pt 2 Suppl 111):1-13.
[7]国家技术监督局.中华人民共和国国家标准:中医临床诊疗术语证候部分[S]. GB/T l6751. 2-1997.
[8]万春,熊墨年,彭翠波,等.益气清毒法介入喉癌患者术后复声的效果评价[J].按摩与康复医学,2012,3(4):17-19.
[9]张义清.化疗配合益气养阴中药治疗晚期喉癌36例临床观察[J].国际中医中药杂志,2009,31(4):335.
[10]李佩文.润肺鸣金法治疗肿瘤患者声音嘶哑[J].疑难病杂志,2005,4(6):323.
[11]苏晓宇.数据挖掘聚类分析方法在中医临床中的应用[J].实用中西医结合临床,2010,10(11):727.
[12]卢标清,李云英,孙一帆,等.喉癌前病变中医证候及四诊特征初步研究[J].世界中西医结合杂志,2012,7(7):579-582.
[2]于华,辛玉芬,段晓东,等.喉癌的流行病学病因学动态分析[J].现代生物医学进展,2007,7(3):393-394.
[3]Jaseviciene L,Gurevicius R,Obelenis V,et al. Trends in laryngeal cancer incidence in Lithuania:a future perspective[J]. Int J Occup Med Environ Health,2004,17(4):473-477.
[4]卢善婷,魏矿荣,余炳辉,等.中山市1970年-1999年喉癌发病趋势分析[J].现代肿瘤医学,2004,12(2):158-160.
[5]Ferlay J,Bray F,Pisani P,et al. Globocan 2000:cancer incidence,mortality and prevalence worldwide[M]. Lyon:IARC press,2001:5.
[6]Hoffman HT,Porter K,Karnell LH,et al. Laryngeal cancer in the United States:changes in demographics,patterns of care,and survival[J].Laryngoscope,2006,116(9 Pt 2 Suppl 111):1-13.
[7]国家技术监督局.中华人民共和国国家标准:中医临床诊疗术语证候部分[S]. GB/T l6751. 2-1997.
[8]万春,熊墨年,彭翠波,等.益气清毒法介入喉癌患者术后复声的效果评价[J].按摩与康复医学,2012,3(4):17-19.
[9]张义清.化疗配合益气养阴中药治疗晚期喉癌36例临床观察[J].国际中医中药杂志,2009,31(4):335.
[10]李佩文.润肺鸣金法治疗肿瘤患者声音嘶哑[J].疑难病杂志,2005,4(6):323.
[11]苏晓宇.数据挖掘聚类分析方法在中医临床中的应用[J].实用中西医结合临床,2010,10(11):727.
[12]卢标清,李云英,孙一帆,等.喉癌前病变中医证候及四诊特征初步研究[J].世界中西医结合杂志,2012,7(7):579-582.