骨刺胶囊的质量标准研究
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摘要
目的建立和提高骨刺胶囊的质量标准。方法采用显微鉴别法对骨刺胶囊中的杜仲、牛膝、熟地和续断进行鉴别;采用薄层色谱法(TLC)对骨刺胶囊中的独活、续断、牛膝和当归药材进行定性鉴别。结果显微特征明显;建立了独活、续断、牛膝和当归药材的薄层鉴别法,TLC斑点清晰,重现性好,专属性强,阴性对照无干扰。结论显微鉴别方法操作简便、准确可靠,耗费少;TLC方法简便可行,结果准确可靠,重复性好,可作为骨刺胶囊的质量控制方法。
Objective To establish and improve quality standard of Guci capsule. Methods Microscopic identification method was used to identify Eucommia, Achyranthes,Radix rehmanniae praeparata and teasel root in Guci capsule;Thin layer chromatography(TLC) was used to identify Angelica,teasel root,Achyranthes and Angelica sinensis in Guci capsule. Results The microscopic characteristics were obvious,TLC methods of Angelica,teasel root,Achyranthes and Angelica sinensis were established.TLC spots were clear with good reproducibility,specificity,negative control without interference. Conclusion Microscopic identification method is simple,accurate and reliable,less waste;TLC method is simple with accurate results and good repeatability,and it can be used as the quality control method of Guci capsule.
Objective To establish and improve quality standard of Guci capsule. Methods Microscopic identification method was used to identify Eucommia, Achyranthes,Radix rehmanniae praeparata and teasel root in Guci capsule;Thin layer chromatography(TLC) was used to identify Angelica,teasel root,Achyranthes and Angelica sinensis in Guci capsule. Results The microscopic characteristics were obvious,TLC methods of Angelica,teasel root,Achyranthes and Angelica sinensis were established.TLC spots were clear with good reproducibility,specificity,negative control without interference. Conclusion Microscopic identification method is simple,accurate and reliable,less waste;TLC method is simple with accurate results and good repeatability,and it can be used as the quality control method of Guci capsule.
引文
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[16]邓小玉,殷婵玉,赵吉平.少林风湿跌打膏质量标准研究[J].湖北中医杂志,2012,34(2):73.
[2]胡世林,冯学锋,唐晓军.中国道地药材原色图说[M].济南:山东科学技术出版社,1998:196,211,348.
[3]曹玲,冯有龙,王亚超,等.骨刺片的质量标准研究[J].中国药品标准,2011,12(3):191-195.
[4]刘桂双,李文军.骨刺消痛胶囊的质量标准研究[J].中医药学报,2009,37(1):45-48.
[5]张湛睿,史亚军,姜建东,等.骨刺消痛胶囊质量标准研究[J].陕西中医,2009,30(6):726.
[6]国家药典委员会.中华人民共和国药典[M].北京:中国医药科技出版社,2010:67,116,124,154,246,309.
[7]王晓一,周昕,陈剑.薄层鉴别法定性鉴别腰疼丸中续断、牛膝报告[J].九江学院学报·自然科学版,2006,21(1):82-83.
[8]袁玲艳,赵永慧,赵嘉琳,等.续断通络胶囊质量标准研究[J].中国实验方剂学杂志,2012,18(2):97.
[9]陈宁,韦英杰,周学敏,等.复方续断胶囊的质量标准研究[J].中国新药杂志,2009,18(23):2283.
[10]卢树杰,张纲,甄兰敏.舒筋通络颗粒中牛膝的薄层色谱鉴别[J].中国药业,2010,19(6):26.
[11]黄荣增,孟军华,吴娟.根痛平胶囊的质量标准研究[J].中国药师,2010,18(4):508.
[12]金珠,位鸿,李秉钧,等.骨痹灵胶囊质量标准研究[J].中成药,2005,27(5):529-532.
[13]杜天信,李洁,杜志谦,等.桃仁膝康丸质量标准研究[J].世界中西医结合杂志,2011,6(6):513.
[14]陈岩,谢培山,颜玉贞.中华人民共和国药典中药薄层色谱彩色图集[M].广州:广东科技出版社,1993:110.
[15]郭亮,郭剑华,马善治,等.膝舒胶囊质量标准研究[J].实用中医药杂志,2012,28(12):1070.
[16]邓小玉,殷婵玉,赵吉平.少林风湿跌打膏质量标准研究[J].湖北中医杂志,2012,34(2):73.