摘要
目的观察益肾种子丸对肾虚精亏型弱精子症患者精子活力的影响。方法将144例患者按随机数字表法分为治疗组(71例)和对照组(73例),治疗过程中脱落10例,完成134例,每组67例。治疗组给予益肾种子丸,每次6 g,每日2次;对照组给予五子衍宗丸,每次6 g,每日2次,两组疗程均为1个月。观察两组患者治疗前后精子活力变化,临床疗效及中医症状评分的变化。结果与本组治疗前比较,治疗后两组a级精子和a+b级精子百分率均增高(P<0.01),且治疗组高于对照组(P<0.05)。治疗组治疗后总有效率为77.61%(52/67),对照组总有效率为58.21%(39/67),两组比较,治疗组优于对照组(Z=-2.914,P=O.004)。与本组治疗前比较,两组治疗后症状积分均降低(P<0.01),治疗组积分差值高于对照组(P<0.01)。结论益肾种子丸治疗肾虚精亏型弱精子症疗效良好,可有效提高精子活力。
Objective To observe the effect of Yishen Zhongzi Pill(YZP) on the sperm motility of Shen-essence deficiency syndrome(SEDS) patients.Methods Totally 144 patients were randomly assigned to the treatment group(71 cases) and the control group(73 cases).Ten cases dropped out during the therapeutic course.A total of 134 patients completed this clinical study,67 in each group.Patients in the treatment group took YZP(6 g each time,twice daily),while those in the control group took Wuzi Yanzong Pill(6 g each time,twice daily).The therapeutic course for all was one month.Changes of the sperm motility,clinical efficacy,and Chinese medical symptoms scores were observed between the two groups before and after treatment.Results Compared with before treatment in the same group,percentages of class a spermatozoa and class a + b spermatozoa were enhanced in the two groups after treatment(P <0.01).Besides,they were higher in treatment group than in the control group(P <0.05).The total effective rate of the treatment group was 77.61%(52/67 cases),while it was 58.21%(39/67cases) in the control group.It was better in the treatment group than in the control group(Z=-2.914,P =0.004).Compared with before treatment in the same group,scores for Chinese medical symptoms decreased in the two groups(P <0.01).The difference of pre-post integrals was higher in the treatment group than in the control group(P <0.01).Conclusion YZP showed favorable effect in treating asthenospermia patients with SEDS and could effectively elevate the motility of sperm.
引文
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