注射毒品致股动脉假性动脉瘤患者血液指标检测分析
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摘要
目的了解注射毒品致股动脉假性动脉瘤患者血液指标的变化情况。方法选择注射毒品致股动脉假性动脉瘤患者(观察组)132例和健康体检者(正常对照组)132例,分别检测2组白细胞(WBC)计数、红细胞(RBC)计数、血小板(PLT)计数及血红蛋白(Hb)、中性粒细胞(NEUT)百分率、淋巴细胞(LYM)比率、红细胞比容(HCT)、红细胞平均体积(MCV)、红细胞平均血红蛋白(MCH)、红细胞分布宽度变异系数(RDW-CV)、红细胞分布宽度标准差(RDW-SD)的水平。结果观察组WBC计数、PLT计数、NEUT百分率和RDW-CV水平均高于正常对照组,RBC计数、Hb、LYM、HCT、MCV、MCH水平均低于正常对照组(均P<0.05);观察组男性WBC计数、PLT计数、NEUT百分率和RDW-CV水平均高于正常对照组,RBC计数、Hb、LYM比率、HCT、MCV、MCH和RDW-SD水平均低于正常对照组(均P<0.05);观察组女性WBC计数、NEUT百分率和RDW-CV水平均高于正常对照组,RBC计数、Hb、LYM比率、HCT、MCV、MCH水平均低于正常对照组(均P<0.05)。结论吸毒会增加股动脉假性动脉瘤患者感染的风险,同时也导致吸毒者贫血,及时治疗和干预是减少股动脉假性动脉瘤并发症的发生、确保手术成功及提高患者生活质量的关键。
Objective To investigate the changes in blood indexes in patients with femoral pseudoaneurysms(FPA)caused by addictive drug injection.Methods White blood cell(WBC)count,red blood cell(RBC)count,platelet(PLT)count,hemoglobin(Hb)level,neutrophil(NEUT)percentage,lymphocyte(LYM)ratio,hematocrit(HCT)value,mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH)concentration,red cell distribution width coefficient variation(RDW-CV)and red blood cell distribution width-standard deviation(RDW-SD)were detected in 132 patients with addictive drug injection-caused FPA(observation group)and132 healthy subjects(control group).Results Compared with control group,WBC count,PLT count,NEUT percentage and RDW-CV increased but RBC count,Hb level,LYM ratio,HCT value,MCV,MCH and RDW-SD decreased in observation group(P<0.05).Compared with males in control group,WBC count,PLT count,NEUT percentage and RDW-CV increased but RBC count,Hb level,LYM ratio,HCT value,MCV,MCH and RDW-SD decreased in males in observation group(P<0.05).Compared with females in control group,WBC count,NEUT percentage and RDW-CV increased but RBC count,Hb level,LYM ratio,HCT value,MCV and MCH decreased in females in observation group(P<0.05).Conclusion Addictive drug injection can increase the risk for FPA and cause anemia.Timely treatment and intervention are important to reduce complications,ensure successful operation and improve the quality of life in patients with addictive drug injection-caused FPA.
Objective To investigate the changes in blood indexes in patients with femoral pseudoaneurysms(FPA)caused by addictive drug injection.Methods White blood cell(WBC)count,red blood cell(RBC)count,platelet(PLT)count,hemoglobin(Hb)level,neutrophil(NEUT)percentage,lymphocyte(LYM)ratio,hematocrit(HCT)value,mean corpuscular volume(MCV),mean corpuscular hemoglobin(MCH)concentration,red cell distribution width coefficient variation(RDW-CV)and red blood cell distribution width-standard deviation(RDW-SD)were detected in 132 patients with addictive drug injection-caused FPA(observation group)and132 healthy subjects(control group).Results Compared with control group,WBC count,PLT count,NEUT percentage and RDW-CV increased but RBC count,Hb level,LYM ratio,HCT value,MCV,MCH and RDW-SD decreased in observation group(P<0.05).Compared with males in control group,WBC count,PLT count,NEUT percentage and RDW-CV increased but RBC count,Hb level,LYM ratio,HCT value,MCV,MCH and RDW-SD decreased in males in observation group(P<0.05).Compared with females in control group,WBC count,NEUT percentage and RDW-CV increased but RBC count,Hb level,LYM ratio,HCT value,MCV and MCH decreased in females in observation group(P<0.05).Conclusion Addictive drug injection can increase the risk for FPA and cause anemia.Timely treatment and intervention are important to reduce complications,ensure successful operation and improve the quality of life in patients with addictive drug injection-caused FPA.
引文
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[10]朱莉莉,施苗盛,赵印敏.吸毒者免疫功能改变的检测及分析[J].检验医学,2013,28(12):1144-1146.
[11]苏宏斌,周兴立,郭曙光,等.注射毒品致股动脉感染性假性动脉瘤破裂出血的外科治疗[J].西南国防医药,2012,22(9):978-979.
[12]Klonaris C,Katsargyris A,Papapetrou A,et al.Infected femoral artery pseudoaneurysm in drug addicts:the beneficial use of the internal iliac artery for arterial Reconstruction[J].J Vasc Surg,2007,45(3):498-504.
[13]孙立伶,刘永东,康中强.感染性股动脉假性动脉瘤破裂出血外科治疗[J].现代医药卫生,2014,30(6):891-893.
[14]Devecioglu M,Settembre N,Samia Z,et al.Treatment of arterial lesions in drug addicts[J].Ann Vasc Surg,2014,28(1):184-191.
[2]杨玉金,颜兴伟,龚俊平,等.吸毒致假性动脉瘤者肝肾功能生化指标检测分析[J].现代预防医学,2012,39(12):3069-3070,3074.
[3]严振辉,洪居陆,柳学国,等.股动脉假性动脉瘤病因及治疗方法分析[J/CD].中国血管外科杂志(电子版),2015,7(2):107-111.
[4]Qiu J,Zhou W,Zhou W,et al.The Treatment of infected femoral artery pseudoaneurysms secondary to drug abuse:11years of experience at a single institution[J].Ann Vasc Surg,2016,36:35-43.
[5]Hu Z J,Wang S M,Li X X,et al.Tolerable hemodynamic changes after femoral artery ligation for the treatment of infected femoral artery pseudoaneurysm[J].Ann Vasc Surg,2010,24(2):212-218.
[6]庞博,刘贵建.血液细胞分析技术的临床应用与研究进展[J].首都医科大学学报,2013,34(4):550-553.
[7]Antoniou G A,Papas T T,Tsagkos I,et al.Endovascular stent-graft repair of bleeding common femoral artery pseudoaneurysm in intravenous drug users:a bridge to surgical reconstruction[J].Vasa,2014,43(6):473-476.
[8]徐媶,刘晓霞.毒品注射性股动脉假性动脉瘤破裂出血围术期护理体会[J].实用临床医药杂志,2015,19(2):125-127.
[9]Sonnenberg G F,Artis D.Innate lymphoid cells in the initiation,regulation and resolution of inflammation[J].Nat Med,2015,21(7):698-708.
[10]朱莉莉,施苗盛,赵印敏.吸毒者免疫功能改变的检测及分析[J].检验医学,2013,28(12):1144-1146.
[11]苏宏斌,周兴立,郭曙光,等.注射毒品致股动脉感染性假性动脉瘤破裂出血的外科治疗[J].西南国防医药,2012,22(9):978-979.
[12]Klonaris C,Katsargyris A,Papapetrou A,et al.Infected femoral artery pseudoaneurysm in drug addicts:the beneficial use of the internal iliac artery for arterial Reconstruction[J].J Vasc Surg,2007,45(3):498-504.
[13]孙立伶,刘永东,康中强.感染性股动脉假性动脉瘤破裂出血外科治疗[J].现代医药卫生,2014,30(6):891-893.
[14]Devecioglu M,Settembre N,Samia Z,et al.Treatment of arterial lesions in drug addicts[J].Ann Vasc Surg,2014,28(1):184-191.