蚕豆根尖微核致突变性试验标准修订背景研究
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摘要
介绍了蚕豆根尖微核致突变性试验及相关微核试验方法的起源和应用情况,重点比较了国内外技术方法在适用范围、受试生物、试验条件参数等方面的差异。在此基础上,对分析仪器发展前景进行了展望,对方法在环境监测管理中的潜在应用方向提出了建议。
Origins and applications of mutagenicity test by Vicia faba root-tip cell micronucleus and other micronucleus test methods were introduced. The differences on scope of application,test organism and test condition parameters of the methods were compared. On the basis,the developments of monitoring instruments were prospected,and the suggestions on the potential applications of the method in environmental monitoring and environmental management were presented.
Origins and applications of mutagenicity test by Vicia faba root-tip cell micronucleus and other micronucleus test methods were introduced. The differences on scope of application,test organism and test condition parameters of the methods were compared. On the basis,the developments of monitoring instruments were prospected,and the suggestions on the potential applications of the method in environmental monitoring and environmental management were presented.
引文
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[2]刘宝森,杨一苗,程士华.“癌症村”接连曝光矛头直指水污染[N].经济参考报,2013-08-12(5).
[3]刚志荣.“中国癌症村”的分布及其地理成因探究[J].中学地理教学参考,2013(11):71-72.
[4]曹佳.微核试验在中国的应用、发展与展望[J].遗传,2003,25(1):73-76.
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[7]SOUGUIR D,FERJANI E,LEDOIGT G.Exposure of Vicia faba and Pisum sativum to copper-induced genotoxicity[J].Protoplasma,2008,233(3-4):203-207.
[8]BARBAFIERI M,GIORGETTI L.Contaminant bioavailability in soil and phytotoxicity/genotoxicity tests in Vicia faba L.:a case study of boron contamination[J].Environ Sci Pollut Res,2016,23(23):24327-24336.
[9]厉以强,周建忠,刘洪.蚕豆根尖微核技术在工业废水遗传毒性监测中的应用[J].环境监测管理与技术,1996,8(3):16-18.
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[18]ISO.ISO 21427-1-2006,Water quality-Evaluation of genotoxicity by measurement of the induction of micronuclei-part 1:Evaluation of genotoxicity using amphibian larvae[S].Geneva:ISO,2006.
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[25]GRANT W F.The present status of higher plant bioassays for the detection of environmental mutagens[J].Mutat Res,1994,310(2):175-185.
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[27]云南省动物研究所二室.食管癌病人放射治疗时外周血淋巴细胞微核率的变化以及和染色体畸变率的关系[J].遗传学报,1978,5(2):142-146.
[28]HEDDLE J A,CIMINO M C,HAYASHI M.Micronuclei as an index of cytogenetic damage:past,present and future[J].Environ Mole Mutagen,1991,18(4):277-291.
[29]中华人民共和国卫生部.GB 7919—1987化妆品安全性评价程序和方法[S].北京:中国标准出版社,1987.
[30]中华人民共和国卫生部.WS/T 187—1999淋巴细胞微核估算受照剂量方法[S].北京:中国标准出版社,1999.
[31]中华人民共和国国家卫生和计划生育委员会.GB 15193.5—2014食品安全国家标准哺乳动物红细胞微核试验[S].北京:中国标准出版社,2014.
[32]中华人民共和国国家质量监督检验检疫总局,中国国家标准化管理委员会.GB/T 21773—2008化学品体内哺乳动物红细胞微核试验方法[S].北京:中国标准出版社,2008.
[33]中华人民共和国国家质量监督检验检疫总局.SN/T 2178—2008危险品哺乳动物红细胞微核试验方法[S].北京:中国标准出版社,2008.
[34]金波,欧光鉴,李明,等.蚕豆(Vicia faba)根尖微核试验敏感品种的筛选[J].华中师范大学学报(自科版),1984(2):101-108.
[35]欧光鉴,金波,陈光荣,等.蚕豆(Vicia faba)根尖微核试验敏感品种筛选的续报[J].华中师范大学学报(自科版),1985(1):87-90.
[36]杨积晴.应用蚕豆根尖细胞微核技术监测环境致突变物的研究进展[J].环境监测管理与技术,1997,9(1):16-18.
[2]刘宝森,杨一苗,程士华.“癌症村”接连曝光矛头直指水污染[N].经济参考报,2013-08-12(5).
[3]刚志荣.“中国癌症村”的分布及其地理成因探究[J].中学地理教学参考,2013(11):71-72.
[4]曹佳.微核试验在中国的应用、发展与展望[J].遗传,2003,25(1):73-76.
[5]余明泽,欧世萍,蒋中仁.微核试验的应用进展[J].预防医学情报杂志,2006,22(6):705-707.
[6]CHEN Y,WANG C X,WANG Z J,et al.Assessment of the contamination and genotoxicity of soil irrigated with wastewater[J].Plant and Soil,2004,261(1-2):189-196.
[7]SOUGUIR D,FERJANI E,LEDOIGT G.Exposure of Vicia faba and Pisum sativum to copper-induced genotoxicity[J].Protoplasma,2008,233(3-4):203-207.
[8]BARBAFIERI M,GIORGETTI L.Contaminant bioavailability in soil and phytotoxicity/genotoxicity tests in Vicia faba L.:a case study of boron contamination[J].Environ Sci Pollut Res,2016,23(23):24327-24336.
[9]厉以强,周建忠,刘洪.蚕豆根尖微核技术在工业废水遗传毒性监测中的应用[J].环境监测管理与技术,1996,8(3):16-18.
[10]王征.急性毒性与遗传毒性体外高通量筛选方法的研究[D].上海:第二军医大学,2004:35-36.
[11]刘瑞祥,边高鹏,兰婷婷.应用小鼠淋巴细胞彗星试验检测地下水遗传毒性[J].环境监测管理与技术,2017,29(3):45-48.
[12]周长慧,常艳,林海霞.遗传毒性标准试验组合结果分析的最新进展[J].中国新药杂志,2010,19(17):1512-1516.
[13]HEDDLE J A.A rapid in vivo test for chromosomal damage[J].Mutat Res,1973,18(2):187-190.
[14]SCHMID W.The micronucleus test[J].Mutat Res,1975,31(1):9-15.
[15]EPA.EPA 712-C-98-226,OPPTS 870.5395,Health effects test guidelines.Mammalian erythrocyte micronucleus test[S].Washington D.C.:EPA,1998.
[16]OECD.Guideline for testing of chemicals No.474,Mammalian erythrocyte micronucleus test[S].Paris:OECD,2014.
[17]OECD.Guideline for testing of chemicals No.487,In vitro mammalian cell micronucleus test[S].Paris:OECD,2015.
[18]ISO.ISO 21427-1-2006,Water quality-Evaluation of genotoxicity by measurement of the induction of micronuclei-part 1:Evaluation of genotoxicity using amphibian larvae[S].Geneva:ISO,2006.
[19]ISO.ISO 21427-2-2006,Water quality-Evaluation of genotoxicity by measurement of the induction of micronuclei-part 2:Mixed population method using the cell line V79[S].Geneva:ISO,2006.
[20]ISO.ISO 29200—2013,Soil quality-Assessment of genotoxic effects on higher plants-Vicia faba micronucleus test[S].Geneva:ISO,2013.
[21]陈思,鲁克庆,马兴铭.微核试验方法及应用研究进展[J].中国比较医学杂志,2016,26(2):83-86.
[22]赵娇红,郭东林,马军.植物微核技术在环境污染监测中的应用[J].自然灾害学报,2007,16(5):126-129.
[23]READ J.Radiation biology of Vicia faba in relation to the general problem[M].London:Black Well Press,1959:59-61.
[24]陈瑞娇,李均祥.蚕豆根尖微核试验在环境致突变物检测中的应用[J].韶关学院学报,2006,27(9):87-91.
[25]GRANT W F.The present status of higher plant bioassays for the detection of environmental mutagens[J].Mutat Res,1994,310(2):175-185.
[26]DEGRASSI F,RIZZONI M.Micronucleus test in Vicia faba root tips to detect mutage damage in fresh water pollution[J].Mutat Res,1982,97:19-33.
[27]云南省动物研究所二室.食管癌病人放射治疗时外周血淋巴细胞微核率的变化以及和染色体畸变率的关系[J].遗传学报,1978,5(2):142-146.
[28]HEDDLE J A,CIMINO M C,HAYASHI M.Micronuclei as an index of cytogenetic damage:past,present and future[J].Environ Mole Mutagen,1991,18(4):277-291.
[29]中华人民共和国卫生部.GB 7919—1987化妆品安全性评价程序和方法[S].北京:中国标准出版社,1987.
[30]中华人民共和国卫生部.WS/T 187—1999淋巴细胞微核估算受照剂量方法[S].北京:中国标准出版社,1999.
[31]中华人民共和国国家卫生和计划生育委员会.GB 15193.5—2014食品安全国家标准哺乳动物红细胞微核试验[S].北京:中国标准出版社,2014.
[32]中华人民共和国国家质量监督检验检疫总局,中国国家标准化管理委员会.GB/T 21773—2008化学品体内哺乳动物红细胞微核试验方法[S].北京:中国标准出版社,2008.
[33]中华人民共和国国家质量监督检验检疫总局.SN/T 2178—2008危险品哺乳动物红细胞微核试验方法[S].北京:中国标准出版社,2008.
[34]金波,欧光鉴,李明,等.蚕豆(Vicia faba)根尖微核试验敏感品种的筛选[J].华中师范大学学报(自科版),1984(2):101-108.
[35]欧光鉴,金波,陈光荣,等.蚕豆(Vicia faba)根尖微核试验敏感品种筛选的续报[J].华中师范大学学报(自科版),1985(1):87-90.
[36]杨积晴.应用蚕豆根尖细胞微核技术监测环境致突变物的研究进展[J].环境监测管理与技术,1997,9(1):16-18.