摘要
利用骨髓间充质干细胞(bone marrow mesenchymal stem cells,BMMSC)和膀胱脱细胞基质(bladder acellular matrix,BAMG)修复、重建膀胱是泌尿外科实验和临床需要解决的难题和热点。虽然报道称BMMSC复合BAMG修复膀胱比单纯BMMSC或BAMG有更好的修复效果,但BMMSC在组织工程膀胱研究中的迁移分化等具体过程和机制依然尚未阐明,故BMMSC在膀胱组织工程的修复路径还需进一步明确。本文主要对间充质干细胞和脱细胞基质的研究现状以及干细胞的染色与归巢的可行性进行综述。
Repairing and reconstructing the Bladder by Bone Marrow Mesenchymal Stem Cells(BMMSC) and running Acellular Matrix BAMG is a difficult and hot topic in urology and clinical practice.Although reported BMMSC composite BAMG bladder repair than simple BMMSC or BAMG has better repair effect,but BMMSC differentiation in the study of tissue engineering bladder migration and so on the specific process and mechanism still has not been clarified,therefore BMMSC in bladder tissue engineering repair path still need to further clarify.In this paper,the current status of mesenchymal stem cells and acellular matrix and the feasibility of stem cell staining and homing are reviewed.
引文
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