孕11～13周~(+6)产前超声筛查胎儿肢体畸形的价值分析
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摘要
目的:探讨孕11~13周~(+6)产前超声在胎儿肢体畸形筛查中的应用价值。方法:研究时间为2015年3月~2018年1月,研究对象为2994例在我院进行产前检查的孕11~13周~(+6)孕妇,所有孕妇均接受产前超声筛查,以引产后或出生后胎儿结果为参照,计算产前超声对胎儿肢体畸形的筛查灵敏度、特异度以及准确率,并采用一致性检验,分析产前超声筛查结果与引产后或出生后胎儿结果之间的一致性。结果:2994例孕妇中,共有40例产前超声检出胎儿肢体畸形,2954例产前超声未检出胎儿肢体畸形,引产后或出生后结果证实有37例胎儿肢体畸形。经计算,产前超声对胎儿肢体畸形的筛查灵敏度、特异度以及准确率分别为91.9%、99.8%、99.7%,与引产后或出生后胎儿结果之间的一致性良好。结论:孕11~13周~(+6)行产前超声可对胎儿肢体畸形予以灵敏检出,可作为胎儿肢体畸形产前筛查的主要手段。
Objective: To investigate the value of prenatal ultrasound for the diagnosis of fetal limb deformities at 11~ 13~(+6) weeks of gestation. Methods: 2994 cases of pregnant women who had pregnancy examination from Mar 2015 to Jan2018 underwent ultrasound examination at their gestational weeks of 11 ~ 13~(+6). Compared with prenatal or postnatal fetal characteristics,the sensitivity,specificity,accuracy and consistency of prenatal ultrasound screening for fetal limb deformities were calculated. Results: Of the 2994 pregnant women,40 cases of fetal limb deformity were detected by prenatal ultrasound and 2954 cases did not found abnomality. 37 cases of fetal limb deformity were confirmed after induction or birth.The sensitivity,specificity and accuracy of prenatal ultrasound for the diagnosis of fetal limb deformity were 91. 9%,99. 8%,and 99. 7%,respectively,which was in good agreement with the results of fetal or postnatal fetal abnormalities.Conclusion: Prenatal ultrasound can be used as the main method to diagnose fetal limb deformities at 11 ~ 13~(+6) weeks of gestation.
Objective: To investigate the value of prenatal ultrasound for the diagnosis of fetal limb deformities at 11~ 13~(+6) weeks of gestation. Methods: 2994 cases of pregnant women who had pregnancy examination from Mar 2015 to Jan2018 underwent ultrasound examination at their gestational weeks of 11 ~ 13~(+6). Compared with prenatal or postnatal fetal characteristics,the sensitivity,specificity,accuracy and consistency of prenatal ultrasound screening for fetal limb deformities were calculated. Results: Of the 2994 pregnant women,40 cases of fetal limb deformity were detected by prenatal ultrasound and 2954 cases did not found abnomality. 37 cases of fetal limb deformity were confirmed after induction or birth.The sensitivity,specificity and accuracy of prenatal ultrasound for the diagnosis of fetal limb deformity were 91. 9%,99. 8%,and 99. 7%,respectively,which was in good agreement with the results of fetal or postnatal fetal abnormalities.Conclusion: Prenatal ultrasound can be used as the main method to diagnose fetal limb deformities at 11 ~ 13~(+6) weeks of gestation.
引文
1邱思花,赖加京,陈淑金,等.超声筛查在胎儿肢体畸形诊断中的临床应用[J].医学影像学杂志,2013,23(11):1843-1846.
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5何冠南,罗红,杨家翔,等.孕11~13周+6产前超声筛查胎儿肢体畸形的价值[J].中国医学影像学杂志,2014,22(8):634-637.
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7刘满荣,唐建华,骆峰,等.超声连续顺序追踪法在胎儿肢体畸形中的诊断价值[J].重庆医学,2013,42(32):3902-3903,3905.
8尹双飞.产前超声对孕14周内胎儿肢体畸形的诊断价值[J].蚌埠医学院学报,2017,42(4):518-520.
2张晓慧,肖利军,邓旦,等.胎儿肢体畸形的产前超声诊断分析[J].重庆医学,2014,43(10):1194-1195,1198.
3焦阳,杜冬,董发进,等.产前超声诊断胎儿肢体畸形的技术探讨[J].中国临床解剖学杂志,2015,33(4):485-487,490.
4查长松,黄月红,戚丽,等.产前超声诊断胎儿肢体畸形的价值[J].中国超声医学杂志,2013,29(2):185-187.
5何冠南,罗红,杨家翔,等.孕11~13周+6产前超声筛查胎儿肢体畸形的价值[J].中国医学影像学杂志,2014,22(8):634-637.
6张丽欣,张爱青,高素红,等.胎儿肢体畸形产前超声诊断价值与漏诊病例分析[J].中国妇幼健康研究,2017,28(10):1214-1217.
7刘满荣,唐建华,骆峰,等.超声连续顺序追踪法在胎儿肢体畸形中的诊断价值[J].重庆医学,2013,42(32):3902-3903,3905.
8尹双飞.产前超声对孕14周内胎儿肢体畸形的诊断价值[J].蚌埠医学院学报,2017,42(4):518-520.