实验动物磁共振成像系统的激光定位仪的制作与应用
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摘要
目的设计研制简易大鼠与小鼠激光定位仪,为医学核磁共振实验提供安全,方便,准确,价格低廉,便于操作的实验工具。方法选用有机玻璃板以及激光定位仪组合拼装制成小动物激光定位仪。结果该小鼠激光定位仪与其他类似产品比较,具有制作简单,安全,基本满足实验要求,价格低廉等优点。结论小动物激光定位仪对小动物核磁检查起到了积极的作用,极大地缩短了实验时间与提高了试验动物摆放位置的精度,为下一步对实验动物进行核磁扫描提供了有力保障。
Objective To design and develop a simple rat and mouse laser locator to provide a safe, convenient, accurate and affordable experimental tool for medical NMR experiments. Method Selected plexiglass plates and laser locator combination assembled into small animal laser locator. Result Compared with other similar products, the mouse laser locator has the advantages of simple and safe manufacture, basically meeting the experimental requirements and low price. Conclusion The small animal laser locator plays an active role in the nuclear magnetic inspection of small animals, which greatly shortens the experiment time and improves the accuracy of the placement of experimental animals, providing a powerful guarantee for the next step of nuclear magnetic resonance scanning of experimental animals.
Objective To design and develop a simple rat and mouse laser locator to provide a safe, convenient, accurate and affordable experimental tool for medical NMR experiments. Method Selected plexiglass plates and laser locator combination assembled into small animal laser locator. Result Compared with other similar products, the mouse laser locator has the advantages of simple and safe manufacture, basically meeting the experimental requirements and low price. Conclusion The small animal laser locator plays an active role in the nuclear magnetic inspection of small animals, which greatly shortens the experiment time and improves the accuracy of the placement of experimental animals, providing a powerful guarantee for the next step of nuclear magnetic resonance scanning of experimental animals.
引文
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[2] 赵建文,曹伟平,银欢,等,固定器的技术要求[J].实验动物科学,2006,23(3):65-66.
[3] 金永柱,将作君.简易小鼠固定器的制作[J].细胞与分子免疫学杂志,2000,16(1):87-87.
[4] 刘如恩,赵洪洋,周伟,等.猫视神经压迫动物模型的建立[J].中华实验外科杂志,2004,21(5):627-628.
[5] 刘如恩,赵洪洋,姜晓兵,等.伽玛刀对猫不同形态视神经病理学影响研究[J].立体定向和功能性神经外科杂志,2005,18(6):4-8.
[6] 何康,冯有辉,罗红梅.不同厂家的戊巴比妥钠对大鼠和家兔麻醉效果的比较[J].实验动物科学.2008,25(1):12-14.
[7] 周传龙,方剑乔,邵晓梅.动物灌注固定方法的探讨[J].实验动物科学.2010,27(1):70-71.