摘要
目的:探讨在脑卒中治疗过程中运用奥拉西坦联合综合康复训练对提高脑卒中患者生活质量的影响。方法将73名脑卒中患者随机组合成为治疗组37例和对照组36例,对照组在一般神经内科治疗后予以综合康复治疗,治疗组在对照组治疗基础上再加用奥拉西坦治疗,两组疗程为2月。指标评价采用美国国立卫生研究院卒中神经功能缺损评分标准(NIHSS)评价神经功能的恢复状况;简易精神状态量表(MMSE)评价认知状况;改良Barthel指数评定患者日常生活能力变化情况。结果:治疗2月后,两组治疗后的NIHSS较前有下降;MMSE、Barthel评分均较前有提高;差异有统计学意义(P<0.05)。治疗组在联合奥拉西坦进行治疗后评价指标分数均明显高于对照组,差异有统计学意义(P<0.05)。结论:奥拉西坦联合综合康复训练能明显提高脑卒中患者认知功能的改善及神经功能的恢复,提高患者日常生活能力,提高了生活质量。
Objective To explore the effect of oxiracetam combined with comprehensive rehabilitation on improving the quality of life of patients with stroke in stroke treatment process. Methods 73 stroke patients were randomly divided into treatment group 37 cases and control group with 36 cases, The control group in the conventional treatment on the basis of neural Department of internal medicine to treatment comprehensive rehabilitation, The treatment group in the control group based on the treatment of combined with Oxiracetam on, The two group was treated for 2 months. Through the application of America National Institutes of Health Stroke neural function defect score standard(NIHSS) to evaluate the recovery of neurological function;Mini Mental State Examination(MMSE) cognitive status evaluation; Daily life ability table(ADL) to score observed in two group with the change of Barthel index of patients were assessed daily life ability. Results After 2 months treatment, the two groups after treatment NIHSS scores were decreased than before; MMSE, Barthel score was improved; The difference was statistically significant(P <0.05). The treatment group were treated in the combined with oxiracetam after control of the scores were significantly better than the control group, The difference was statistically significant(P < 0.05). Conclusion Oxiracetam combined can obvio comprehensive rehabilitation usly improve the function and nerve function of patients with cognitive brain recovery, improve the ability of daily life of patients, improve the quality of life.
引文
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