摘要
目的探讨抗生素相关性腹泻的临床特征、影响因素及预防措施。方法回顾性分析2014年1月~2015年6月入院治疗的102例抗生素相关性腹泻患者的基本资料、抗生素相关性腹泻的发生时间及类型、抗生素使用情况以及治疗方法和疾病转归等。结果抗生素相关性腹泻的发生率为3.75%;粪便性状以稀水泡沫样便为主,占70.59%;有71.57%的患者抗生素使用时间超过1周,抗生素联合使用者占72.55%;引起抗生素相关性腹泻的抗生素按照发生频次依次为头孢菌素类、碳青霉烯类和喹诺酮类;90.2%的患者经治疗后能痊愈或好转。结论抗生素相关性腹泻的发生与多种因素有关,合理使用抗生素是预防抗生素相关性腹泻的关键,应引起广泛重视。
Objective To investigate the clinical characteristics, influence factors and preventive measures of antibiotic-associated diarrhea(AAD).Methods The basic information,thedisease time of AAD, antibiotics' application, therapy methods and prognosis of 102 cases with AAD were retrospectively analyzed. Results The incidence of AAD was 3.75%. Concerningproperty of stool was predominant, accounting for 70.59%. The ones utilized antibiotics more than one week was 72.55% and the ones utilized multiple antibiotics was 72.55%. According to the frequency, the antibiotics which cause AAD were cephalosporin, carbapenem and quinolone. The diarrhea patients of 90.2% could relieve or get better. Conclusion The occurrence of AAD was associated withmany factors. Rational use of antibiotics is the key to prevent antibiotic-associated diarrhea which should be paid wide attention.
引文
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