摘要
目的:对比限定限定与非限定骨盆骨髓剂量在宫颈癌术后调强放疗靶区剂量学中的差异。方法:选取于我院接受宫颈癌外科根治术的60例患者作为研究对象。采用随机数表法将其分为观察组与对照组,观察组30例在调强放疗计划设计时要求对骨盆骨髓受照剂量、体积进行限制,而对照组30例不限制骨盆骨髓受照剂量,比较两组患者靶区剂量学的差异。结果:观察组骨盆10Gy、20Gy、40Gy剂量明显低于对照组(P<0.05),但两组在肿瘤靶区覆盖率、膀胱与直肠的Dmean比较无显著差异(P<0.05)。结论:在调强放疗计划中限定骨盆骨髓剂量能够有效减少宫颈癌患者骨盆的照射剂量,并且不会增加肿瘤靶区覆盖率以及周围器官的照射剂量。
Objective:to compare qualified qualified and unqualified pelvic bone marrow dose in the target area of dosimetry difference in postoperative uterine cervix cancer.Method:selection in 60 patients with cervical cancer surgery in our patients as the research object.All patients with postoperative clinical target area according to the target sketch with the involvement of organs,by using stochastic indicator will be divided into the observation group and control group and observation group of 30 cases in radiotherapy planning the design requirements of pelvic bone marrow to restrict,the dose and volume in 30 cases and control group received conventional radiotherapy plan without pelvic bone marrow illuminated dose limit,compared two groups of patients dosimetry difference of target Results:observation group pelvic 10 gy,20 gy,40 gy dose significantly lower than the control group(P < 0.05),but the two groups in tumor target area coverage,bladder and rectum Dmean is no significant difference(P < 0.05).Conclusions:in radiotherapy planning limited pelvic bone marrow dose can effectively reduce cervical cancer patients with pelvic irradiation dose,and doesnt increase the tumor dose of target area coverage and the surrounding organs.
引文
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