基于超分子组装的纳米荧光探针
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- 英文论文题名：Nano-fluorescence-probes based on supramolecular assemblies
- 论文作者：宋波
- 英文论文作者：Bo Song ; College of Chemistry ; Chemical Engineering and Materials Science ; Soochow University
- 年：2016
- 作者机构：苏州大学,材料与化学化工学部;
- 论文关键词：超分子组装 ; 生物呈像 ; 离子检测 ; 有机荧光探针
- 会议召开时间：2016-07-01
- 会议录名称：中国化学会第30届学术年会摘要集-第二十四分会：超分子组装与软物质材料
- 语种：中文
- 分类号：O657.3;TB383.1
- 学会代码：ZGHY
- 会议名称：中国化学会第30届学术年会-第二十四分会 ; 超分子组装与软物质材料
- 会议地点：中国辽宁大连
- 主办单位：中国化学会
- 学会名称：中国化学会
- 页数：1
- 文件大小：143k
- 原文格式：D
- 会议级别：全国
摘要
有机荧光材料优异的发光性能在生物相关领域的应用越来越受到关注。但荧光染料本身因聚集而引起的发光不稳定性、芳香基团固有的疏水性等特点往往会降低发光强度以及在生物体系中的分散性,从而限制其应用范围。超分子组装体系为调控有机分子的构象和聚集状态,提高其荧光量子效率,以及改善与生物体系的相容性提供了理想的载体。如Fig.1所示,我们希望利用超分子组装的多样性、可控性及裁剪性等特点,将具有荧光性的染料基团引入构筑基元,发展制备具有发光位置可控、荧光量子效率高、生物相容性好、以及生物毒性低等特点的纳米结构材料的方法。在此基础上,筛选出发光性能和相容性好的纳米荧光组装体,并探索这些组装体作为荧光探针在生物呈像及离子检测等方面的应用。
Organic fluorescence materials are attracting more and more research attention owing to their unique emission properties. For different type of dye molecules(no matter traditional ACQ or new developed AIE), the applications in bio-related systems were limited by the instable emission caused by un-expected aggregation, the inherent hydrophobicity of aromatics, and reduced fluorescence quantum yield. Supramolecular self-assemblies supply ideal vehicles for tuning the configuration and aggregation of dyes, enhancing the quantum yield, and improving the bio-compatibility of the materials. Herein, we would like to utilize the versatility, flexibility and tailorability of supramolecular assemblies to explore new strategies of fabricating nanostructured materials with controllable emitting position, high quantum yield, good bio-compatibility and low toxicity. On this basis, the selected materials will be employed as fluorescence probes and applied on bio-imaging or ionic detections.
Organic fluorescence materials are attracting more and more research attention owing to their unique emission properties. For different type of dye molecules(no matter traditional ACQ or new developed AIE), the applications in bio-related systems were limited by the instable emission caused by un-expected aggregation, the inherent hydrophobicity of aromatics, and reduced fluorescence quantum yield. Supramolecular self-assemblies supply ideal vehicles for tuning the configuration and aggregation of dyes, enhancing the quantum yield, and improving the bio-compatibility of the materials. Herein, we would like to utilize the versatility, flexibility and tailorability of supramolecular assemblies to explore new strategies of fabricating nanostructured materials with controllable emitting position, high quantum yield, good bio-compatibility and low toxicity. On this basis, the selected materials will be employed as fluorescence probes and applied on bio-imaging or ionic detections.
引文
[1]Jin,Y.;Wang,S.;Zhang,Y.;Song,B.,Sensors and Actuators B:Chemical 2016,225:167.
[2]Yin,S.;Dong,L.;Xia,Y.;Dong,B.;He,X.;Chen,D.;Qiu,H.;Song,B.,Soft Matter 2015,11:4424.
[3]Xia,Y.;Dong,L.;Jin,Y.;Wang,S.;Yan,L.;Yin,S.;Zhou,S.;Song,B.,J.Mater.Chem.B 2015,3:491.
[4]Jin,Y.;Xia,Y.;Wang,S.;Yan,L.;Zhou,Y.;Fan,J.;Song,B.,Soft Matter 2015,11,798.
[2]Yin,S.;Dong,L.;Xia,Y.;Dong,B.;He,X.;Chen,D.;Qiu,H.;Song,B.,Soft Matter 2015,11:4424.
[3]Xia,Y.;Dong,L.;Jin,Y.;Wang,S.;Yan,L.;Yin,S.;Zhou,S.;Song,B.,J.Mater.Chem.B 2015,3:491.
[4]Jin,Y.;Xia,Y.;Wang,S.;Yan,L.;Zhou,Y.;Fan,J.;Song,B.,Soft Matter 2015,11,798.