基于(2-羟基苯基)苯并恶唑母体荧光探针合成与应用
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- 英文论文题名：Synthesis and application of fluorescent probe based on 2-(2-Hydroxyphenyl)benzoxazole
- 论文作者：贺永桓 ; 尚玉婷 ; 陈卫华
- 英文论文作者：Yonghuan he ; Yuting shang ; Weihua chen ; Institute of Food Science and Technology ; Chinese Academy of Agricultural Sciences
- 年：2016
- 作者机构：中国农业科学院农产品加工研究所;
- 论文关键词：食品安全 ; 荧光 ; (2-羟基苯基)苯并恶唑
- 会议召开时间：2016-07-01
- 会议录名称：中国化学会第30届学术年会摘要集-第二十七分会：光化学
- 语种：中文
- 分类号：O657.3
- 学会代码：ZGHY
- 会议名称：中国化学会第30届学术年会-第二十七分会 ; 光化学
- 会议地点：中国辽宁大连
- 主办单位：中国化学会
- 学会名称：中国化学会
- 页数：1
- 文件大小：172k
- 原文格式：D
- 会议级别：全国
摘要
随着我国经济水平的发展,人们对生活质量的要求愈发提高。近年来,农产品质量安全问题日显重要。目前农产品安全检测主要依赖仪器手段,如质谱、色谱等仪器分析技术,该类技术准确、可靠,但检测时存在周期长、专业依赖性强、费用较高、设备昂贵等不利因素,因此难以实时快速地监控农产品安全状况。在目前监管分散、样本分散以及样本量不均的情况下,采用现场快速检测对样本进行初步筛查,将可疑样品进行进一步仪器确证,可以极大地提高检测效率,适合我国小农模式下农产品分散种植、零散加工的具体国情。我们选取具有灵敏度高、检出限低、操作简单、易于化学合成、环境要求较生物制剂宽松、易于长期保存和使用优势的(2-羟基苯基)苯并恶唑分子为荧光母体,通过与2.4-二硝基苯磺酰氯反应,制备出对巯基类物质有专一性响应的荧光探针。
We choose(2- hydroxy phenyl) benzoxazole molecules with high sensitivity, low detection limit, simple operation, easy to chemical synthesis, and broad biological agents environment, easy to long-term preservation and use of the advantages as the starting materials to synthesize the target fluorescent probe. After being reacted with 2.4- dinitrobenzene sulfonyl chloride reaction, the fluorescent probe was obtained, which response to sulphur class material and had a potential application in the field of food safety and detection.
We choose(2- hydroxy phenyl) benzoxazole molecules with high sensitivity, low detection limit, simple operation, easy to chemical synthesis, and broad biological agents environment, easy to long-term preservation and use of the advantages as the starting materials to synthesize the target fluorescent probe. After being reacted with 2.4- dinitrobenzene sulfonyl chloride reaction, the fluorescent probe was obtained, which response to sulphur class material and had a potential application in the field of food safety and detection.
引文
[1]Chen,W.;Pang,Y.Tetrahedron Lett.2009,50:6680-6683
[2]Chen,W.;Wright,B.D.;Pang,Y.Chem.Commun.2012,48:3824-3826
[2]Chen,W.;Wright,B.D.;Pang,Y.Chem.Commun.2012,48:3824-3826