摘要
目的:观察消炎生肌膏在促进湿热下注型低位单纯性肛瘘术后创面愈合中的作用。
方法:本研究观察的60例湿热下注型低位单纯性肛瘘术后患者均为福建中医学院附属人民医院肛肠科2007年1月至2007年12月住院病人,其中男性44例,女性16例,年龄18岁～57岁。按随机数字表将所有患者随机分成治疗组30例,对照组30例。两组患者性别、年龄、病程、手术创面面积均无显著性差异,具有可比性。手术在肛周局部浸润麻醉下行低位肛瘘切开术。治疗组患者自术后第1天开始用消炎生肌膏换药,对照组患者自术后第1天开始用雷弗诺尔纱条换药。在治疗过程中,分别记录用药前及用药后第2、4、6天两组病例创面疼痛、创缘水肿和创面渗液积分情况;用药后第14、21、28天测算创面愈合率;创面愈合时间;用药后第28天观察总体疗效。
结果:1用药后第28天总体疗效比较:治疗组治愈率为96.67%,对照组治愈率为80.00%,两组间疗效比较有显著性差异。2创面愈合时间比较:治疗组创面愈合时间为11～30天,平均愈合时间21.20天,对照组创面愈合时间为16～34天,平均愈合时间23.93天,两组间创面愈合时间有显著性差异。3创面愈合率比较:两组组内比较,用药后第14天与用药后第21天均差异显著;两组组间比较,用药后第14、21天均有显著差异。4用药前后两组问症状、体征积分比较:用药前两组间均无显著性差异;两组组内比较,用药前与用药后第6天均差异显著;两组组间比较,用药后第2、4、6天两组创面疼痛与创面渗液积分均有显著性差异,而两组创缘水肿积分无显著性差异。5用药过程中两组未发现明显不良反应。
结论:消炎生肌膏能有效缓解术后创面疼痛、创缘水肿,减少创面渗液,促进创面愈合。它对湿热下注型低位单纯性肛瘘术后创面有良好的治疗作用,疗效优于雷弗诺尔纱条,是一种安全有效的中药制剂。
Objective:To observe the Xiaoyanshengji ointment's effect on wounds healing after the operation of low-set simple anal fistula of downward flow damp-heat.
Methods:The Clinical study of 60 patients with the operation of low-set simple anal fistula of downward flow damp-heat was conducted in the Hospital of Traditional Chinese Medicine in FuJian province from January to December in 2007,of them male were 44 cases, and female were 16 cases,at the age of patients was 18～57.Sixty patients after the operation of anal fistula are divided into the treatment group(30 cases) and the control group(30 cases) randomly.The difference between the two groups on sex,age,the course of disease and the area of wound surface were not significant.Low-set anal fistula took to cut open in local infiltration anesthesia.The treatment group was given Xiaoyanshengji ointment on wounds at the first day after the operation of anal fistula;the later Rivanol at the same day.Made records of both group's anal aches,anal swelling and anal surface seep in the day before treatment and the second,fourth,and sixth day after operation.Then made statistics according to the records. Made observation of wounds healing rates in the fourteenth,twenty-first and twenty-eighth day,wounds healing time and total therapeutic effect in the twenty-eighth day.
Result:1 In the twenty-eighth day,the cure rate of the treatment group was 96.67%, the cure rate of the control group was 80.00%.The total therapeutic effect of the two group is distinctly different.2 After treated with the treatment group,the healing time of surface was 11～30 days,the average healing time of raw surface was 21.20 days,while the later was 16～34 days and 23.93 days.The healing time of raw surface was significant different between the two groups.3 The wounds healing rate between the fourteenth and twenty-first day was significant different in the treatment group and the control group.The wounds healing rate in the fourteenth and twenty-first day was significant different between the treatment group and the control group.4 As for the curative effect of the symptom such as anal aches,anal swelling and anal surface seep,there was no significant different between the treatment group and the control group before treatment.The effect between the day before treatment and the sixth day after operation was significant different in the treatment group and the control group. The effect of lessening pains and anal surface seep in the second,fourth and sixth day after operation was significant different between the treatment group and the control group.But in reducing anal surface seep,there is no obvious difference between the treatment group and the control group in the second,fourth and sixth day after operation.5 There is no obviously side effect in the treatment.
Conclusion.Xiaoyanshengji ointment has significant effects on the complications.It can alleviate anal aches,lessen anal swelling and anal surface seep,and promote the wounds healing after operation.It can heal the wounds alter the operation of low-set simple anal fistula of downward flow damp-heat very well.It is better than Rivanol.The Chinese drugs pharmaceutics is safe and effective.
引文
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