头部刺血疗法为主治疗偏头痛的临床研究
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摘要
研究目的：
观察应用头部刺血疗法为主治疗偏头痛的临床疗效,并以单纯西药治疗偏头痛作为对照组,比较其两种方法的疗效差异,试图探究一个行之有效、经济安全的治疗偏头痛的优佳方法。
研究方法：
1.病例选择：将60例符合研究病例标准的偏头痛患者,采用随机数字表法随机分成两组：治疗组(头部刺血疗法为主组)和对照组(西药对照组),其中治疗组30例,对照组30例。
2.治疗方法：2组病例患者的病情、病程、年龄等基本情况具有可比性。
(1)治疗组取穴：耳尖(患侧)、百会穴,双侧曲泽、内关、外关、阳辅、太冲、蠡沟、足三里、涌泉。耳尖(患侧)、百会穴采用点刺放血法；双侧曲泽、内关、外关、阳辅、太冲、蠡沟采用普通针刺法；足三里、涌泉采用艾灸疗法。
(2)对照组口服盐酸氟桂利嗪(西比灵),lOmg,每次1次,睡前服。如患者头痛较严重可临时口服布洛芬缓释胶囊0.3g(芬必得),头痛缓解后停服。
3.疗程：针灸各疗法均隔日操作1次,每周操作3次后休息1天,1周为一疗程,治疗4周,西药对照组连续口服治疗4周,随后连续观察1月后评估疗效。疗效评定包括：头痛的疼痛程度(视觉模拟评分VAS法)、头痛的发作次数、头痛持续时间、伴随症状等。
研究结果：
1.两组患者治疗前、后VAS评分比较
治疗前两组患者头痛VAS评分经统计学分析,P>0.05,差异无统计学意义；两组患者治疗前、后头痛VAS评分比较,经统计学t检验分析,P<0.05。治疗4个疗程后,两组患者头痛VAS评分相比较,差异无统计学意义(P>0.05)。
2.两组患者治疗前、后头痛发作次数评分的比较
治疗前两组患者头痛发作次数评分经统计学分析,P>0.05,差异无统计学意义；两组患者治疗前、后头痛发作次数评分比较,经统计学t检验分析,P<0.05,差异有统计学意义。治疗4个疗程后,两组患者头痛发作次数评分相比较,差异无统计学意义(P>0.05)。
3.两组患者治疗前、后头痛程度评分的比较
治疗前两组患者头痛程度评分经统计学分析,P>0.05,差异无统计学意义；两组患者治疗前、后头痛程度评分比较,经统计学t检验分析,P<0.05,差异有统计学意义。治疗4个疗程后,两组患者头痛程度评分相比较,差异无统计学意义(P>0.05)。
4.两组患者治疗前、后头痛持续时间评分比较
治疗前两组头痛持续时间评分经统计学分析,P>0.05,差异无统计学意义；两组病例治疗前、后头痛持续时间评分比较,经统计学t检验分析,P<0.05,差异有统计学意义；经治疗后两组头痛持续时间评分比较,经统计学t检验分析,P>0.05,差异无统计学意义。
5.两组患者治疗前、后头痛伴随症状评分比较
治疗前两组头痛伴随症状评分经统计学分析,P>0.05,差异无统计学意义。两组病例治疗前、后头痛伴随症状评分比较,经统计学t检验分析,治疗组经治疗后头痛伴随症状评分较治疗前明显降低,P<0.05,差异有统计学意义；对照组经治疗后头痛伴随症状评分较治疗前无明显变化,P>0.05,差异无统计学意义。经治疗4个疗程后,两组头痛伴随症状评分比较,经统计学t检验分析,P<0.05,差异有统计学意义。
6.两组疗效评定比较
经x2检验,两组比较疗效比较,P>0.05,由此可见,两组治愈率、显效率、有效率之间无显著差异,结果表明两种方法均为治疗偏头痛有效方法,可供临床选用,两种疗法之间无显著差异。
结论：
治疗前后两组组内比较,头痛发作次数、头痛程度、头痛持续时间、伴随症状均有显著性差异(0.05),表明两种治疗方法均能明显改善偏头痛的症状,取得良好的疗效；治疗后两组间比较,头痛发作次数、头痛程度、头痛持续时间相比较,均无显著性差异(P>0.05),表明两种治疗方法在总体疗效上无显著差异：两组伴随症状评分比较,有显著差异(P<0.05),表明在改善偏头痛伴随症状方面,头部刺血疗法为主优于西药对照组。
Objective:
To observe the clinical effects of treating Migraine by the acupuncture therapy mainly with pricking blood therapy on the head, meanwhile to compare the clinical effects of the acupuncture therapy mainly with pricking blood therapy on the head and conventional methods. Try to find a effective, economic and safe way to treat such patients. The effective method can light the side effect of medical, decrease the recurrence rate, elevate the life quality and survival rate, lessen the patients' economic burden and so on.
Methods:
1. Sixty cases of Migraine received the treatment who met the clinical research requirements were randomly divided into two groups, which including the acupuncture therapy mainly with pricking blood therapy on the head group (Treatment group,30cases), Control group (30cases).
2. The information of the patients of two groups, such as duration, age and other basic situations have no significant differences.
(1) Treatment group Acupoint:Erjian point (Ipsilateral), Baihui point, Quchi point(Ipsilateral), Neiguan point(Ipsilateral), Waiguan point (Ipsilateral), Yangfu point (Ipsilateral), Taichong point(Ipsilateral), Ligou point(Ipsilateral), Zusanli point(Ipsilateral), Yongquan point (Ipsilateral). The main points, Erjian point (Ipsilateral), Baihui point, take the pricking blood therapy. Such points as Quchi point(Ipsilateral), Neiguan point (Ipsilateral), Waiguan point (Ipsilateral), Yangfu point (Ipsilateral), Taichong point(Ipsilateral), Ligou point(Ipsilateral), Zusanli point(Ipsilateral), Yongquan point (Ipsilateral)take the Moxibustion.
(2)Control group Each patient was treated with Flunarizine Hydrochloride Capsules for10mg before bedtime everyday, in case of sever headache, these patients can take ibuprofen sustained-release capsules for0.3g temporary.
3. Period of treatment:The frequency of acupunction is once2days, three times a week,1week is one course, the observation time is4weeks. The index include:VAS, the number of headache attacks, Headache duration, associated symptoms, and so on.
Results:
1.The comparison of the score of VAS
Before treatment, there were no significant differences between the two groups on the score of VAS (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the two groups on the score of VAS (P<0.05). After4weeks therapies, there were no significant differences between the two groups on the score of VAS (P>0.05).
2. The comparison of the score of the number of headache attacks
Before treatment, there were no significant differences between the two groups on the score of the number of headache attacks (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the two groups on the score of the number of headache attaeks (P<0.05). After4weeks therapies, there were no significant differences between the two groups on the score of the number of headache attacks (P>0.05).
3. The comparison of the score of the headache severity
Before treatment, there were no significant differences between the two groups on t the score of the headache severity (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the two groups on the score of the headache severity(P<0.05). After4weeks therapies, there were no significant differences between the two groups on the score of the headache severity (P>0.05).
4. The comparison of the score of the headache duration
Before treatment, there were no significant differences between the two groups on t the score of the headache duration (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the two groups on the score of the headache duration(P<0.05). After4weeks therapies, there were no significant differences between the two groups on the score of the headache duration (P>0.05).
5. The comparison of the score of the associated symptoms
Before treatment, there were no significant differences between the two groups on the score of the associated symptoms (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the treatment group on the score of the associated symptoms(P<0.05), there were no significant difference in the control group on the score of the associated symptoms (P>0.05). After4weeks therapies, there were no significant differences between the two groups on the score of the associated symptoms(P>0.05).
6.The comparison of the curative effect of the two groups
The acupuncture therapy mainly with pricking blood therapy and the therapy of Flunarizine Hydrochloride Capsules all have good curative effect. The total effective rate is:the treatment group76.67%; the control group70%, there were no significant differences (P>0.05).
Conclusion:
The method of acupuncture therapy mainly with pricking blood therapy and Flunarizine Hydrochloride Capsules are effective in treating simple obesity. The efficacy of the two kinds of therapy is equal. But, in the aspect of improving migraine symptoms, The method of acupuncture therapy mainly with pricking blood therapy on the head is more effective than The method of Flunarizine Hydrochloride Capsules.
观察应用头部刺血疗法为主治疗偏头痛的临床疗效,并以单纯西药治疗偏头痛作为对照组,比较其两种方法的疗效差异,试图探究一个行之有效、经济安全的治疗偏头痛的优佳方法。
研究方法：
1.病例选择：将60例符合研究病例标准的偏头痛患者,采用随机数字表法随机分成两组：治疗组(头部刺血疗法为主组)和对照组(西药对照组),其中治疗组30例,对照组30例。
2.治疗方法：2组病例患者的病情、病程、年龄等基本情况具有可比性。
(1)治疗组取穴：耳尖(患侧)、百会穴,双侧曲泽、内关、外关、阳辅、太冲、蠡沟、足三里、涌泉。耳尖(患侧)、百会穴采用点刺放血法；双侧曲泽、内关、外关、阳辅、太冲、蠡沟采用普通针刺法；足三里、涌泉采用艾灸疗法。
(2)对照组口服盐酸氟桂利嗪(西比灵),lOmg,每次1次,睡前服。如患者头痛较严重可临时口服布洛芬缓释胶囊0.3g(芬必得),头痛缓解后停服。
3.疗程：针灸各疗法均隔日操作1次,每周操作3次后休息1天,1周为一疗程,治疗4周,西药对照组连续口服治疗4周,随后连续观察1月后评估疗效。疗效评定包括：头痛的疼痛程度(视觉模拟评分VAS法)、头痛的发作次数、头痛持续时间、伴随症状等。
研究结果：
1.两组患者治疗前、后VAS评分比较
治疗前两组患者头痛VAS评分经统计学分析,P>0.05,差异无统计学意义；两组患者治疗前、后头痛VAS评分比较,经统计学t检验分析,P<0.05。治疗4个疗程后,两组患者头痛VAS评分相比较,差异无统计学意义(P>0.05)。
2.两组患者治疗前、后头痛发作次数评分的比较
治疗前两组患者头痛发作次数评分经统计学分析,P>0.05,差异无统计学意义；两组患者治疗前、后头痛发作次数评分比较,经统计学t检验分析,P<0.05,差异有统计学意义。治疗4个疗程后,两组患者头痛发作次数评分相比较,差异无统计学意义(P>0.05)。
3.两组患者治疗前、后头痛程度评分的比较
治疗前两组患者头痛程度评分经统计学分析,P>0.05,差异无统计学意义；两组患者治疗前、后头痛程度评分比较,经统计学t检验分析,P<0.05,差异有统计学意义。治疗4个疗程后,两组患者头痛程度评分相比较,差异无统计学意义(P>0.05)。
4.两组患者治疗前、后头痛持续时间评分比较
治疗前两组头痛持续时间评分经统计学分析,P>0.05,差异无统计学意义；两组病例治疗前、后头痛持续时间评分比较,经统计学t检验分析,P<0.05,差异有统计学意义；经治疗后两组头痛持续时间评分比较,经统计学t检验分析,P>0.05,差异无统计学意义。
5.两组患者治疗前、后头痛伴随症状评分比较
治疗前两组头痛伴随症状评分经统计学分析,P>0.05,差异无统计学意义。两组病例治疗前、后头痛伴随症状评分比较,经统计学t检验分析,治疗组经治疗后头痛伴随症状评分较治疗前明显降低,P<0.05,差异有统计学意义；对照组经治疗后头痛伴随症状评分较治疗前无明显变化,P>0.05,差异无统计学意义。经治疗4个疗程后,两组头痛伴随症状评分比较,经统计学t检验分析,P<0.05,差异有统计学意义。
6.两组疗效评定比较
经x2检验,两组比较疗效比较,P>0.05,由此可见,两组治愈率、显效率、有效率之间无显著差异,结果表明两种方法均为治疗偏头痛有效方法,可供临床选用,两种疗法之间无显著差异。
结论：
治疗前后两组组内比较,头痛发作次数、头痛程度、头痛持续时间、伴随症状均有显著性差异(0.05),表明两种治疗方法均能明显改善偏头痛的症状,取得良好的疗效；治疗后两组间比较,头痛发作次数、头痛程度、头痛持续时间相比较,均无显著性差异(P>0.05),表明两种治疗方法在总体疗效上无显著差异：两组伴随症状评分比较,有显著差异(P<0.05),表明在改善偏头痛伴随症状方面,头部刺血疗法为主优于西药对照组。
Objective:
To observe the clinical effects of treating Migraine by the acupuncture therapy mainly with pricking blood therapy on the head, meanwhile to compare the clinical effects of the acupuncture therapy mainly with pricking blood therapy on the head and conventional methods. Try to find a effective, economic and safe way to treat such patients. The effective method can light the side effect of medical, decrease the recurrence rate, elevate the life quality and survival rate, lessen the patients' economic burden and so on.
Methods:
1. Sixty cases of Migraine received the treatment who met the clinical research requirements were randomly divided into two groups, which including the acupuncture therapy mainly with pricking blood therapy on the head group (Treatment group,30cases), Control group (30cases).
2. The information of the patients of two groups, such as duration, age and other basic situations have no significant differences.
(1) Treatment group Acupoint:Erjian point (Ipsilateral), Baihui point, Quchi point(Ipsilateral), Neiguan point(Ipsilateral), Waiguan point (Ipsilateral), Yangfu point (Ipsilateral), Taichong point(Ipsilateral), Ligou point(Ipsilateral), Zusanli point(Ipsilateral), Yongquan point (Ipsilateral). The main points, Erjian point (Ipsilateral), Baihui point, take the pricking blood therapy. Such points as Quchi point(Ipsilateral), Neiguan point (Ipsilateral), Waiguan point (Ipsilateral), Yangfu point (Ipsilateral), Taichong point(Ipsilateral), Ligou point(Ipsilateral), Zusanli point(Ipsilateral), Yongquan point (Ipsilateral)take the Moxibustion.
(2)Control group Each patient was treated with Flunarizine Hydrochloride Capsules for10mg before bedtime everyday, in case of sever headache, these patients can take ibuprofen sustained-release capsules for0.3g temporary.
3. Period of treatment:The frequency of acupunction is once2days, three times a week,1week is one course, the observation time is4weeks. The index include:VAS, the number of headache attacks, Headache duration, associated symptoms, and so on.
Results:
1.The comparison of the score of VAS
Before treatment, there were no significant differences between the two groups on the score of VAS (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the two groups on the score of VAS (P<0.05). After4weeks therapies, there were no significant differences between the two groups on the score of VAS (P>0.05).
2. The comparison of the score of the number of headache attacks
Before treatment, there were no significant differences between the two groups on the score of the number of headache attacks (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the two groups on the score of the number of headache attaeks (P<0.05). After4weeks therapies, there were no significant differences between the two groups on the score of the number of headache attacks (P>0.05).
3. The comparison of the score of the headache severity
Before treatment, there were no significant differences between the two groups on t the score of the headache severity (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the two groups on the score of the headache severity(P<0.05). After4weeks therapies, there were no significant differences between the two groups on the score of the headache severity (P>0.05).
4. The comparison of the score of the headache duration
Before treatment, there were no significant differences between the two groups on t the score of the headache duration (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the two groups on the score of the headache duration(P<0.05). After4weeks therapies, there were no significant differences between the two groups on the score of the headache duration (P>0.05).
5. The comparison of the score of the associated symptoms
Before treatment, there were no significant differences between the two groups on the score of the associated symptoms (P>0.05). After4weeks therapies, compared with scores before the treatment, there were significant difference in the treatment group on the score of the associated symptoms(P<0.05), there were no significant difference in the control group on the score of the associated symptoms (P>0.05). After4weeks therapies, there were no significant differences between the two groups on the score of the associated symptoms(P>0.05).
6.The comparison of the curative effect of the two groups
The acupuncture therapy mainly with pricking blood therapy and the therapy of Flunarizine Hydrochloride Capsules all have good curative effect. The total effective rate is:the treatment group76.67%; the control group70%, there were no significant differences (P>0.05).
Conclusion:
The method of acupuncture therapy mainly with pricking blood therapy and Flunarizine Hydrochloride Capsules are effective in treating simple obesity. The efficacy of the two kinds of therapy is equal. But, in the aspect of improving migraine symptoms, The method of acupuncture therapy mainly with pricking blood therapy on the head is more effective than The method of Flunarizine Hydrochloride Capsules.
引文
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