广东地区不同季节供精者精液参数变化分析
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摘要
目的通过了解广东地区不同季节供精志愿者精液参数的变化,为捐精志愿者最佳捐精时间提供证据。方法对广东省人类精子库供精志愿者在2016年采集的精液分析结果进行回顾性分析。结果 2016年共分析15 341份精液样本,3 582名供精志愿者,年龄22~45岁。精液量平均为3.70 m L,春、夏、秋、冬季分别为3.79、3.65、3.67和3.73 m L,春季略高于其他3季;精子浓度平均91.5×106/m L,春、夏、秋、冬季分别为93.3×106/m L、91.5×106/m L、89.7×106/m L和92.7×106/m L,仅春季明显高于秋季(P<0.05);前向运动精子百分率平均为56.7%,春、夏、秋、冬季分别为58.5%、55.1%、57.1%、57.0%,春季明显高于夏、秋、冬3个季节(P<0.05)。结论季节因素对供精志愿者精液参数有影响,春季精液量多、精子浓度高、前向运动精子百分率高,是捐精的最佳季节。
Objective To examine parameter changes in semen from donors in different seasons in Guangdong province and to provide evidences for determining the best time for sperm donation. Methods We analyzed 15 341 semen specimens donated by 3 582 volunteers aged 22 – 45 years to Guangdong provincial human sperm bank in 2016. Results The averagesemen volume was 3.70 ml for all the sperm donations and the average volume were 3.79 ml, 3.65 ml, 3.67 ml, and 3.73 ml for the sperm donations collected in spring, summer, autumn, and winter season, respectively, with a slightly higher volume for the semen collected in spring season. The average sperm concentration was 91.5 × 106/ml for all the semen donations and the average concentration were 93.3 × 106/ml, 91.5 × 106/ml, 89.7 × 106/ml, and 92.7 × 106/ml for the semen donations collected in spring, summer, autumn, and winter season; the average sperm concentration was significantly higher for the semen donations collected in spring season compared to that in autumn season(P < 0.05). The average sperm motility was56.7% for all the semen donations and the average motility were 58.5%, 55.1%, 57.1%, and 57.0% for the semen donations collected in spring, summer, autumn, and winter season; the sperm motility was significantly higher for the semen donations collected in spring season compared to that of those collected in other seasons(P < 0.05). Conclusion Seasonal factors have influence on parameters of semen donations from volunteers. The volume, sperm concentration and motility are higher for semen donations collected in spring season and spring is the best season for collecting semen donations.
Objective To examine parameter changes in semen from donors in different seasons in Guangdong province and to provide evidences for determining the best time for sperm donation. Methods We analyzed 15 341 semen specimens donated by 3 582 volunteers aged 22 – 45 years to Guangdong provincial human sperm bank in 2016. Results The averagesemen volume was 3.70 ml for all the sperm donations and the average volume were 3.79 ml, 3.65 ml, 3.67 ml, and 3.73 ml for the sperm donations collected in spring, summer, autumn, and winter season, respectively, with a slightly higher volume for the semen collected in spring season. The average sperm concentration was 91.5 × 106/ml for all the semen donations and the average concentration were 93.3 × 106/ml, 91.5 × 106/ml, 89.7 × 106/ml, and 92.7 × 106/ml for the semen donations collected in spring, summer, autumn, and winter season; the average sperm concentration was significantly higher for the semen donations collected in spring season compared to that in autumn season(P < 0.05). The average sperm motility was56.7% for all the semen donations and the average motility were 58.5%, 55.1%, 57.1%, and 57.0% for the semen donations collected in spring, summer, autumn, and winter season; the sperm motility was significantly higher for the semen donations collected in spring season compared to that of those collected in other seasons(P < 0.05). Conclusion Seasonal factors have influence on parameters of semen donations from volunteers. The volume, sperm concentration and motility are higher for semen donations collected in spring season and spring is the best season for collecting semen donations.
引文
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[10]张迅,梁季鸿,梁世坤,等.季节因素对精液参数的影响[J].中华中医药杂志,2015,30(6):1913-1915.
[11]Künzle R,Mueller MD,Huber AW.Seasonality in human semen quality of smokers and non-smokers:effect of temperature[J].Asian Journal of Andrology,2004,6(3):243-247.
[12]舒金辉,吴柱连,李学余,等.广西地区男性精液质量与季节因素的关系分析[J].中国卫生检验杂志,2016,26(16):2386-2387.
[13]张欣宗,姚康寿.季节因素对精子形态的影响[J].中国优生与遗传杂志,2008,16(7):93-94.
[14]杨东,鲜红,腾文顶,等.精液质量与季节关系探讨[J].四川医学,2010,31(8):1098-1099.
[15]Lunge G.Impact of seasonal variation,age and smoking status on human semen parameters:the Massachusetts General Hospital experience[J].Journal of Experimental and Clinical Assisted Reproduction,2004,1(1):2-7.
[16]熊承良,吴明章,刘继红,等主编.人类精子学[M].北京:人民卫生出版社,2013,243-244.
[2]Rolland M,Moal JL,Wagner V,et al.Decline in semen concentration and morphology in a sample of 26,609 men close to general population between 1989 and 2005 in France[J].Human Reproduction,2013,28(2):462-470.
[3]黄莉萍,李亚斐,熊鸿燕,等.近25年中国正常男性精液质量的变化趋势分析[J].生殖与避孕,2011,31(2):122-128.
[4]黄跃辉.精液质量影响因素的调查研究[D].武汉:华中科技大学,2014.
[5]赵世荣.影响精液质量的因素[J].职业与健康,2012,28(14):1780-1782.
[6]WHO.人类精液检查与处理实验室手册[M].5版,北京:人民卫生出版社,2011.5-43.
[7]中华人民共和国国家卫生和计划生育委员会.人类精子库基本标准和技术规范[S].卫科教发(2003)176号.
[8]Levitas E,Lunenfeld E,Weisz N,et al.Seasonal variations of human sperm cells among 6455 semen samples:a plausible explanation of a seasonal birth pattern[J].American Journal of Obstetrics and Gynecology,2013,208(5):1-6.
[9]Yogev L,Kleiman S,Shabtai E,et al.Seasonal variations in preand post-thaw donor sperm quality[J].Human Reproduction,2004,19(4):880-885.
[10]张迅,梁季鸿,梁世坤,等.季节因素对精液参数的影响[J].中华中医药杂志,2015,30(6):1913-1915.
[11]Künzle R,Mueller MD,Huber AW.Seasonality in human semen quality of smokers and non-smokers:effect of temperature[J].Asian Journal of Andrology,2004,6(3):243-247.
[12]舒金辉,吴柱连,李学余,等.广西地区男性精液质量与季节因素的关系分析[J].中国卫生检验杂志,2016,26(16):2386-2387.
[13]张欣宗,姚康寿.季节因素对精子形态的影响[J].中国优生与遗传杂志,2008,16(7):93-94.
[14]杨东,鲜红,腾文顶,等.精液质量与季节关系探讨[J].四川医学,2010,31(8):1098-1099.
[15]Lunge G.Impact of seasonal variation,age and smoking status on human semen parameters:the Massachusetts General Hospital experience[J].Journal of Experimental and Clinical Assisted Reproduction,2004,1(1):2-7.
[16]熊承良,吴明章,刘继红,等主编.人类精子学[M].北京:人民卫生出版社,2013,243-244.