摘要
目的研究阿奇霉素联合标准桃金娘油治疗急性气管-支气管炎的临床疗效,并分析其安全性。方法选择该院2014年3月—2017年3月期间所收治的70例急性气管-支气管炎患者作为该次研究对象,该70例患者全部符合急性气管-支气管炎治疗标准,根据患者入院的时间进行分组治疗,单日期为研究组,双日期为对照组,每组35例,对照组患者应用阿奇霉素治疗,研究组患者在此基础上加用标准桃金娘油治疗,对比分析两组患者的临床疗效,并观察两组患者的平均病程和不良反应发生情况。结果研究组患者的临床治疗总有效率(91.43%)显著高于对照组(68.57%),组间数据对比差异有统计学意义差异有统计学意义(χ~2=5.714 3,P=0.016 8)。研究组胃肠道反应发生率为8.57%,显著低于对照组(25.57%),组间数据对比(χ~2=4.628 9,P=0.031 4)。研究组患者平均病程为(11.21±2.12)d,明显短于对照组(14.52±2.97)d,组间数据对比差异有统计学意义(t=5.366 4,P=0.000 0)。结论阿奇霉素与标准桃金娘油联合治疗急性气管-支气管炎的效果显著,能够有效改善患者的生活质量和临床症状,且具有较高的安全性,值得临床进一步推广应用。
Objective This paper tries to study the clinical efficacy of azithromycin combined with standard myrtol oil in the treatment of acute tracheobronchitis and to analyze its safety. Methods 70 patients with acute tracheobronchitis admitted in this hospital from March 2014 to March 2017 were selected as the subject of this study. All 70 patients met the criteria of acute tracheobronchitis treatment according to the time of admission. Different therapy methods were used due to the admission date of the patients, single date for the study group, double date for the control group, 35 cases for each group, the control group patients were treated with azithromycin, the study group patients were treated with standard myrtas oil, and the two groups of patients were compared and analyzed. Clinical efficacy, the average course of disease and adverse reactions in the two groups of patients were observed. Results The total effective rate of clinical treatment in the study group(91.43%) was significantly higher than that of the control group(68.57%). there was statistically significant differences between groups(χ~2=5.714 3, P=0.016 8). The incidence of gastrointestinal reactions in the study group was 8.57%, which was significantly lower than that in the control group(25.57%). there was statistically significant differences between groups(χ~2=4.628 9, P=0.031 4). The average duration of disease in the study group was(11.21±2.12) days, which was significantly shorter than that in the control group(14.52±2.97)days. there was statistically significant differences between groups(t=5.366 4,P=0.000 0). Conclusion The combination of azithromycin and standard myrtle oil in the treatment of acute tracheal-bronchitis has a significant effect, can effectively improve the patient's quality of life and clinical symptoms, and has a higher safety, it is worthy of further clinical application.
引文
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