针刺治疗60例肿瘤伴发焦虑抑郁患者的临床研究
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摘要
[目的]观察针刺对肿瘤相关性焦虑、抑郁及生活质量的临床疗效。[方法]将60例肿瘤患者随机分为针刺组和西药组,针刺组针刺合谷、内关、太冲、阳陵泉等穴位;西药组予盐酸舍曲林片(左洛复)治疗,2组均连续治疗4周。观察两组患者生活质量核心问卷(Quality of Life QuestionnaireCore 30,QLQ-C30)、汉密尔顿焦虑量表(Hamilton Anxiety Scale,HAMA)和抑郁量表(Hamilton Depression Scale,HAMD)评分的变化情况。[结果]治疗后,两组与治疗前相比,HAMA及HAMD评分均明显降低(P<0.05),且治疗后4周,西药组改善焦虑抑郁程度及其在情绪功能的单项评分显著优于针刺组(P<0.05),但针刺组治疗后4周在疲乏、恶心呕吐、失眠、食欲减退、角色功能及总体生活质量单项评分改善明显优于西药组(P<0.05)。[结论]针刺在提高肿瘤相关性焦虑、抑郁的临床疗效的同时,能帮助改善肿瘤患者常见伴发症状并提高其生活质量,可在临床推广运用。
[Objective]To observe the acupuncture correlation with the clinical curative effect of anxiety, depression and quality of life.[Methods] The 60 patients with tumor were randomly divided into acupuncture group and western medicine group, acupuncture group acupunctured Neiguan(P6),Taichong(Liv3),Yanglingquan(SP9) and other acupuncture points.The western medicine group was treated with Sertraline Hydrochloride tablets(Zoloft) and2 groups were treated for 4 weeks consecutively. The changes in the quality of life of the two groups(QLQ-C30),Hamilton anxiety scale(HAMA) and depression scale(HAMD) were observed. [Results]Two groups were compared with before treatment, HAMA and HAMD scores were significantly lower( P<0.05), and 4 weeks after treatment, western medicine improved the degree of anxiety depression and score of emotional function was significantly better than that of acupuncture group(P<0.05),but after the acupuncture treatment group 4 weeks fatigue, nausea and vomiting, insomnia, loss of appetite, role function and overall quality of life of individual score improved significantly better than western medicine group( P<0.05).[Conclusion]The clinical effect of acupuncture on improving tumor related anxiety and depression is not as good as the improvement of Western medicine, but it can help to improve the common symptoms of cancer patients and improve the quality of life, and can be used in clinical application.
[Objective]To observe the acupuncture correlation with the clinical curative effect of anxiety, depression and quality of life.[Methods] The 60 patients with tumor were randomly divided into acupuncture group and western medicine group, acupuncture group acupunctured Neiguan(P6),Taichong(Liv3),Yanglingquan(SP9) and other acupuncture points.The western medicine group was treated with Sertraline Hydrochloride tablets(Zoloft) and2 groups were treated for 4 weeks consecutively. The changes in the quality of life of the two groups(QLQ-C30),Hamilton anxiety scale(HAMA) and depression scale(HAMD) were observed. [Results]Two groups were compared with before treatment, HAMA and HAMD scores were significantly lower( P<0.05), and 4 weeks after treatment, western medicine improved the degree of anxiety depression and score of emotional function was significantly better than that of acupuncture group(P<0.05),but after the acupuncture treatment group 4 weeks fatigue, nausea and vomiting, insomnia, loss of appetite, role function and overall quality of life of individual score improved significantly better than western medicine group( P<0.05).[Conclusion]The clinical effect of acupuncture on improving tumor related anxiety and depression is not as good as the improvement of Western medicine, but it can help to improve the common symptoms of cancer patients and improve the quality of life, and can be used in clinical application.
引文
[1]秦宏图,马依.护理干预对妇科恶性肿瘤病人抑郁焦虑心理状况的影响[J].航空航天医学杂志,2015,26(9):1145-1146.
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[4]中华中医药学会血液病分会.肿瘤相关抑郁状态中医诊疗专家共识[J].中华中医药杂志,2015,30(12):4397-4399.
[5]高树中,杨骏.针灸治疗学[M].9版.北京:中国中医药出版社,2012:78.
[6]杨红,郑世利.社会支持对门诊化疗肿瘤患者焦虑抑郁情绪的影响[J].国际护理学杂志,2015,34(16):2167-2171.
[7]王晓星.加味逍遥颗粒改善肿瘤相关性抑郁的临床研究[D].北京中医药大学,2013:58.
[8]程和瑞,翟西菊,亓德美,等.奥氮平治疗伴肿瘤相关性焦虑抑郁肿瘤的疗效观察[J].社区医学杂志,2015,13(4):28-30.
[9]郎卫红,赵艳茹.脑卒中后抑郁的发病机制以及相关影响因素研究进展[J].赤峰学院学报(自然科学版),2010,26(2):66-68.
[10]王玉伟,杨丽芹,曹丽华.归因训练合并舍曲林治疗惊恐障碍疗效观察[J].精神医学杂志,2011,24(5):353-355.
[11]韩健勇,尤艳丽.浅谈合谷临床镇痛作用[J].针灸临床杂志,2011,27(1):70-72.
[2]魏立君.胃肠道恶性肿瘤患者焦虑抑郁状态及其影响因素[J].现代肿瘤医学,2015,23(19):2802-2804.
[3]李元娥.整体护理干预对肿瘤化疗患者疲乏及焦虑抑郁的影响[J].内科,2015,10(5):743-744.
[4]中华中医药学会血液病分会.肿瘤相关抑郁状态中医诊疗专家共识[J].中华中医药杂志,2015,30(12):4397-4399.
[5]高树中,杨骏.针灸治疗学[M].9版.北京:中国中医药出版社,2012:78.
[6]杨红,郑世利.社会支持对门诊化疗肿瘤患者焦虑抑郁情绪的影响[J].国际护理学杂志,2015,34(16):2167-2171.
[7]王晓星.加味逍遥颗粒改善肿瘤相关性抑郁的临床研究[D].北京中医药大学,2013:58.
[8]程和瑞,翟西菊,亓德美,等.奥氮平治疗伴肿瘤相关性焦虑抑郁肿瘤的疗效观察[J].社区医学杂志,2015,13(4):28-30.
[9]郎卫红,赵艳茹.脑卒中后抑郁的发病机制以及相关影响因素研究进展[J].赤峰学院学报(自然科学版),2010,26(2):66-68.
[10]王玉伟,杨丽芹,曹丽华.归因训练合并舍曲林治疗惊恐障碍疗效观察[J].精神医学杂志,2011,24(5):353-355.
[11]韩健勇,尤艳丽.浅谈合谷临床镇痛作用[J].针灸临床杂志,2011,27(1):70-72.