基于数据挖掘初探古代服饵辟谷方剂用药规律
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摘要
目的:探索古代中医文献中服饵辟谷方剂的用药规律,为临床应用与辟谷养生提供参考。方法:以《中华医典》(第五版)为方剂数据资源,参考图书馆资料,搜集查找出108首方剂,采用Excel 2016、SPSS Modeler 14.1、SPSS 22.0软件对药物进行频数分析、关联规则分析和聚类分析,研究辟谷方用药规律。结果:108首服饵辟谷方剂共涉及107味中药,其中常用食物类药物、药食同源类药物及可用于保健品类药物共有67味,占62.62%;频次≥8的常用药物有16味,分别为茯苓、蜂蜜、蜂蜡、黑大豆、松香、大枣、火麻仁、天门冬、糯米、侧柏叶、白术、黑芝麻、粳米、小麦、人参、甘草;在所有药物与常用药物中甘味药、平性药与归脾经药使用均最多;常见配伍有茯苓与天门冬、蜂蜜与天门冬、茯苓与蜂蜡等。结论:服饵辟谷组方选药首重安全,尽量选择无毒无害服用安全性高的药物;总体上用药平和,以甘味药与平性药为主,遵循甘缓平补之法;用药多归脾肺二经,着重调节辟谷期间体内气的生化与运行。
Objective: To analysis on the medication rule of prescriptions for inedia and daoist pills in ancient TCM literature, which provide evidence for its clinical application and health preservation with inedia. Methods: With Encyclopadia of Traditional Chinese Medicine(the fifth edition) as the prescription data resource, 108 prescriptions were collected by referring to the materials from library. The frequency, association rules and cluster analysis of medicine was carried out to study the medication rule of inedia by using Excel 2016, SPSS Modeler 14.1 and SPSS 22.0 software. Results: A total of 107 Chinese herbs were involved in the 108 prescriptions for inedia and for daoist health preservation, among which, 67 were used as food, both medicine and food and health care products, accounting for 62.62%. A total of 16 of common Chinese herbs was used no less than8 times, namely, poria, honey, beewax, black soybean, rosin, Chinese date, fructus cannabis, asparagus cochinchinensis, sticky rice, cacumen biotae, white atractylodes rhizome, black sesame, polishedround-grainedrice, wheat, Ginseng and Liquorice. Among all Chinese herbs or common medicine, those taste sweet or with even property or those with channeltropism of spleen were used the most. The common drug combinations included poria and asparagus cochinchinensis, honey and asparagus cochinchinensis,and poria and beewax. Conclusion: The safety of medicine is firstly considered when making prescriptions for inedia and for daoist health preservation, and non-toxic Chinese herbs with top safety and less side effects are selected as much as possible. As a whole, the Chinese herbs selected are with mild property. They mostly taste sweet or with even property following the principle of mild tonification with sweet Chinese herbs in even property. The medicine used is mainly with channel tropism of spleen and lung,focusing on regulating the transformation and production and movement of qi during the inedia.
Objective: To analysis on the medication rule of prescriptions for inedia and daoist pills in ancient TCM literature, which provide evidence for its clinical application and health preservation with inedia. Methods: With Encyclopadia of Traditional Chinese Medicine(the fifth edition) as the prescription data resource, 108 prescriptions were collected by referring to the materials from library. The frequency, association rules and cluster analysis of medicine was carried out to study the medication rule of inedia by using Excel 2016, SPSS Modeler 14.1 and SPSS 22.0 software. Results: A total of 107 Chinese herbs were involved in the 108 prescriptions for inedia and for daoist health preservation, among which, 67 were used as food, both medicine and food and health care products, accounting for 62.62%. A total of 16 of common Chinese herbs was used no less than8 times, namely, poria, honey, beewax, black soybean, rosin, Chinese date, fructus cannabis, asparagus cochinchinensis, sticky rice, cacumen biotae, white atractylodes rhizome, black sesame, polishedround-grainedrice, wheat, Ginseng and Liquorice. Among all Chinese herbs or common medicine, those taste sweet or with even property or those with channeltropism of spleen were used the most. The common drug combinations included poria and asparagus cochinchinensis, honey and asparagus cochinchinensis,and poria and beewax. Conclusion: The safety of medicine is firstly considered when making prescriptions for inedia and for daoist health preservation, and non-toxic Chinese herbs with top safety and less side effects are selected as much as possible. As a whole, the Chinese herbs selected are with mild property. They mostly taste sweet or with even property following the principle of mild tonification with sweet Chinese herbs in even property. The medicine used is mainly with channel tropism of spleen and lung,focusing on regulating the transformation and production and movement of qi during the inedia.
引文
[1]方克立,卢育三,吕希晨.中国哲学大辞典.北京:中国社会科学出版社,1994:708
[2]国家中医药管理局《中华本草》编委会.中华本草.上海:上海科学技术出版社,1999
[3]中华人民共和国国家卫生和计划生育委员会.卫生部关于进一步规范保健食品原料管理的通知.http://www.nhfpc.gov.cn/zwgkzt/wsbysj/200810/38057.shtml
[4]国家卫生计生委食品安全标准与监测评估司.国家卫生计生委办公厅关于征求《按照传统既是食品又是中药材物质目录管理办法》(征求意见稿)意见的函.http://www.nhfpc.gov.cn/sps/s3585/201411/67ac54fb05ed46929adc63f2db31d4bf.shtml
[5]秦华珍,邓家刚,刘颖,等.平性药与平性药性.南京中医药大学学报,2012,28(3):201-203
[6]清·陈修园.神农本草经读.伍悦,点校.北京:学苑出版社,2011
[7]明·李中梓.雷公炮制药性解.钱允治,补订.北京:人民军医出版社,2013
[2]国家中医药管理局《中华本草》编委会.中华本草.上海:上海科学技术出版社,1999
[3]中华人民共和国国家卫生和计划生育委员会.卫生部关于进一步规范保健食品原料管理的通知.http://www.nhfpc.gov.cn/zwgkzt/wsbysj/200810/38057.shtml
[4]国家卫生计生委食品安全标准与监测评估司.国家卫生计生委办公厅关于征求《按照传统既是食品又是中药材物质目录管理办法》(征求意见稿)意见的函.http://www.nhfpc.gov.cn/sps/s3585/201411/67ac54fb05ed46929adc63f2db31d4bf.shtml
[5]秦华珍,邓家刚,刘颖,等.平性药与平性药性.南京中医药大学学报,2012,28(3):201-203
[6]清·陈修园.神农本草经读.伍悦,点校.北京:学苑出版社,2011
[7]明·李中梓.雷公炮制药性解.钱允治,补订.北京:人民军医出版社,2013