摘要
目的:探究儿童慢性咳嗽的病因分布。方法:选取在我院儿科门诊就诊的慢性咳嗽患儿1 888例,分析其慢性咳嗽的病因。结果:小儿慢性咳嗽的病因由高到低依次为变态反应性哮喘(49.2%)、咳嗽变异性哮喘(35.3%)、上气道咳嗽综合征(8.8%)和肺炎支原体感染(6.7%);<3岁患儿咳嗽病因变态反应性哮喘所占比例最高达60.9%,而3~6岁患儿咳嗽变异性哮喘比例最高达43.1%,7~12岁儿童变态反应性哮喘比例达47.7%;各年龄段的病因构成比存在差异,具有统计学意义(P<0.05)。结论:小儿慢性咳嗽病因中,第1位是变态反应性哮喘,其次病因依次为咳嗽变异性哮喘和上气道咳嗽综合征,不同年龄患儿慢性咳嗽的主要病因不同。
Objective: To explore the etiological distribution of chronic cough in children. Methods: 1 888 children with chronic cough admitted to the pediatric outpatient department of our hospital were selected. The causes of chronic cough were analyzed. Results: The causes of chronic cough in children were allergic asthma(49.2%), cough variant asthma(35.3%), upper airway cough syndrome(8.8%) and mycoplasma pneumoniae infection(6.7%). The proportion of allergic asthma caused by cough in children aged less than 3 years old was up to 60.9%, that of cough variant asthma in children aged 3~6 years old was up to 43.1%, and that of allergic asthma in children aged 7~12 years old was up to 47.7%. There were significant differences in etiological composition among different age groups(P<0.05). Conclusion: Allergic asthma is the first cause of chronic cough in children, followed by cough variant asthma and upper airway cough syndrome. The main causes of chronic cough vary with age.
引文
[1] 中华医学会儿科学分会呼吸学组慢性咳嗽协作组.中国儿童慢性咳嗽诊断与治疗指南(2013年修订)[J].中华儿科杂志,2014,52(3):184-188.
[2] 李丽.成人慢性咳嗽的病因分布及相关影响因素分析[J].中国医药指南,2016,14(10):27.
[3] 涂亚兰,应波.儿童慢性咳嗽病因诊治分析及预防体会[J].中华全科医学,2014,12(3):497-498.
[4] 刘秋海,徐浩岑,邢燕如,等.咳嗽变异性哮喘在儿童慢性咳嗽中发病率的调查研究[J].中国医刊,2014(6):67-69.
[5] 唐燕,吕进泉,张凡,等.慢性咳嗽儿童生活质量研究[J].临床儿科杂志,2014,32(7):668-671.
[6] 王津津.成人不明原因慢性咳嗽病因分析[J].临床医学研究与实践,2016,1(9):50.
[7] 罗泽民,蔡艳,刘蓓蓓,等.不同年龄儿童慢性咳嗽病因分析[J].临床儿科杂志,2011,29(2):138-141.
[8] 覃勇民,刘学冠.咳嗽变异性哮喘的研究进展[J].内科,2017,12(5):41-42,45.
[9] 黄穗,王金华,黄顺开,等.广州市儿童变应性疾病流行病学调查分析[J].中华实用儿科临床杂志,2011,26(21):1629-1631.
[10] 袁海斌,成莲英,陶莹,等.湘潭市0~14岁儿童哮喘流行病学调查[J].中国妇幼保健,2012,27(1):98-99.