臭氧联合射频消融治疗神经根型颈椎病的临床效果
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摘要
目的探讨臭氧联合射频消融治疗神经根型颈椎病的临床效果。方法选择我院2016年12月至2018年11月收治的90例神经根型颈椎病患者作为研究对象,根据治疗方法的不同将其分为参照组与研究组,每组45例。参照组采用射频消融治疗,研究组则采用臭氧联合射频消融治疗。比较两组患者治疗效果以及治疗前、后的疼痛情况、hs-CRP、IL-6及IL-8水平。结果研究组治疗总有效率高于参照组,差异具有统计学意义(P<0.05);治疗后,研究组的VAS评分、hs-CRP、IL-6及IL-8水平均低于参照组,差异具有统计学意义(P<0.05)。结论采用臭氧联合射频消融治疗神经根型颈椎病,不但能够缓解患者疼痛并消除炎症,还能提高患者的免疫功能,应用价值高。
Objective To investigate the clinical effect of ozone combined with radiofrequency ablation in the treatment of cervical spondylotic radiculopathy. Methods Ninety patients with cervical spondylotic radiculopathy treated in our hospital from December 2016 to November 2018 were selected as research objects. According to different treatment methods, the patients were divided into reference group and study group, with 45 cases in each group. The reference group was treated with radiofrequency ablation, while the study group was treated with ozone combined with radiofrequency ablation. The therapeutic effect, pain condition, levels of hs-CRP, IL-6 and IL-8 before and after treatment were compared between the two groups. Results The total effective rate of treatment in the study group was significantly higher than that of the reference group, the difference was statistically significant(P<0.05). After treatment, the VAS score, levels of hs-CRP, IL-6 and IL-8 of the study group were lower than those of the reference group, the differences were statistically significant(P <0.05).Conclusion Ozone combined with radiofrequency ablation in the treatment of cervical spondylotic radiculopathy can not only relieve pain and eliminate inflammation, but also improve the immune function of patients, with high application value.
Objective To investigate the clinical effect of ozone combined with radiofrequency ablation in the treatment of cervical spondylotic radiculopathy. Methods Ninety patients with cervical spondylotic radiculopathy treated in our hospital from December 2016 to November 2018 were selected as research objects. According to different treatment methods, the patients were divided into reference group and study group, with 45 cases in each group. The reference group was treated with radiofrequency ablation, while the study group was treated with ozone combined with radiofrequency ablation. The therapeutic effect, pain condition, levels of hs-CRP, IL-6 and IL-8 before and after treatment were compared between the two groups. Results The total effective rate of treatment in the study group was significantly higher than that of the reference group, the difference was statistically significant(P<0.05). After treatment, the VAS score, levels of hs-CRP, IL-6 and IL-8 of the study group were lower than those of the reference group, the differences were statistically significant(P <0.05).Conclusion Ozone combined with radiofrequency ablation in the treatment of cervical spondylotic radiculopathy can not only relieve pain and eliminate inflammation, but also improve the immune function of patients, with high application value.
引文
[1]寇久社,吴涛,张润宁,等.不同质量浓度医用臭氧联合射频消融对兔骨骼肌损伤组织学与IL-6的影响[J].临床和实验医学杂志,2017,16(24):2415-2419.
[2]史传岗,徐小青.臭氧联合射频消融治疗对神经根型颈椎病患者疼痛及hs-CRP、IL-6、IL-8的影响[J].中国地方病防治杂志,2017,32(8):892-893.
[3]吴霆,胡咏兵,姚咏玲,等.靶点射频热凝联合椎管前间隙注射臭氧联合射频消融治疗腰椎间盘突出症的效果观察[J].中国处方药2018,16(4):6-7.
[4]周广明.医用臭氧联合射频消融在疼痛治疗的应用[J].医学信息2018,31(11):67-69.
[5]李刚,叶试南,敖威.小针刀联合臭氧联合射频消融治疗膝骨性关节炎的临床研究[J].中医临床研究,2018,10(10):28-29.
[6]蔡中奇.椎旁神经阻滞联合臭氧联合射频消融治疗腰椎间盘突出的应用评价[J].临床研究,2018,26(10):82-83.
[7]孟利锋,贺竟哲.膝痛熏洗方熏洗配合臭氧联合射频消融注射治疗膝关节骨性关节炎对IL-1β、TNF-α的影响[J].实用中医药杂志2018,34(9):1055-1056.
[8]孙艳林,曹剑青,张宝喜.低浓度臭氧联合射频消融治疗膝关节骨性关节炎临床观察[J].中西医结合心血管病电子杂志,2018,6(27)188-189.
[9]蔡振华,陈丹丹,周华成,等.臭氧对糖尿病神经病理性疼痛大鼠的镇痛作用[J].中国疼痛医学杂志,2012,18(4):205-208.
[10]张守平,魏健,李鹏.臭氧联合射频消融治疗糖尿病周围神经病理性疼痛72例临床观察[J].中国疼痛医学杂志,2017,23(3):236-237,240.
[11]崔文海,王永.臭氧联合射频消融灌肠对溃疡性结肠炎疗效及血清IL-6含量影响观察[J].临床医药文献:电子版,2017,4(12):2313,2315.
[12]贾杰海,董妍含,丁宇,等.针刀联合射频、臭氧联合射频消融治疗神经根型颈椎病的临床研究[J].世界中医药,2017,12(6):1436-1438,1442.
[13]张永俊,袁岩,何晓峰,等.射频消融联合臭氧联合射频消融治疗神经根型颈椎病的临床效果[J].江苏医药,2016,42(2):181-182.
[14]吴昊,周文来.不同浓度医用臭氧联合射频消融治疗膝关节骨性关节炎的疗效及对TNF-α和IL-6的影响[J].现代中西医结合杂志,2015,24(16):1782-1784.
[15]徐传华.臭氧联合射频消融治疗对神经根型颈椎病患者疼痛及TNF-α的影响[J].免疫学杂志,2014,30(3):274-276.
[16]徐传华,张利君.臭氧对腰椎间盘突出症患者TNF-α和IL-6的影响[J].中华全科医学,2014,12(2):316-317.
[17]于密生,刘志奇,宋建梅,等.颈椎旁与硬膜外阻滞联合臭氧联合射频消融治疗神经根型颈椎病的疗效观察[J].河北医药,2014,36(11):1707-1709.
[2]史传岗,徐小青.臭氧联合射频消融治疗对神经根型颈椎病患者疼痛及hs-CRP、IL-6、IL-8的影响[J].中国地方病防治杂志,2017,32(8):892-893.
[3]吴霆,胡咏兵,姚咏玲,等.靶点射频热凝联合椎管前间隙注射臭氧联合射频消融治疗腰椎间盘突出症的效果观察[J].中国处方药2018,16(4):6-7.
[4]周广明.医用臭氧联合射频消融在疼痛治疗的应用[J].医学信息2018,31(11):67-69.
[5]李刚,叶试南,敖威.小针刀联合臭氧联合射频消融治疗膝骨性关节炎的临床研究[J].中医临床研究,2018,10(10):28-29.
[6]蔡中奇.椎旁神经阻滞联合臭氧联合射频消融治疗腰椎间盘突出的应用评价[J].临床研究,2018,26(10):82-83.
[7]孟利锋,贺竟哲.膝痛熏洗方熏洗配合臭氧联合射频消融注射治疗膝关节骨性关节炎对IL-1β、TNF-α的影响[J].实用中医药杂志2018,34(9):1055-1056.
[8]孙艳林,曹剑青,张宝喜.低浓度臭氧联合射频消融治疗膝关节骨性关节炎临床观察[J].中西医结合心血管病电子杂志,2018,6(27)188-189.
[9]蔡振华,陈丹丹,周华成,等.臭氧对糖尿病神经病理性疼痛大鼠的镇痛作用[J].中国疼痛医学杂志,2012,18(4):205-208.
[10]张守平,魏健,李鹏.臭氧联合射频消融治疗糖尿病周围神经病理性疼痛72例临床观察[J].中国疼痛医学杂志,2017,23(3):236-237,240.
[11]崔文海,王永.臭氧联合射频消融灌肠对溃疡性结肠炎疗效及血清IL-6含量影响观察[J].临床医药文献:电子版,2017,4(12):2313,2315.
[12]贾杰海,董妍含,丁宇,等.针刀联合射频、臭氧联合射频消融治疗神经根型颈椎病的临床研究[J].世界中医药,2017,12(6):1436-1438,1442.
[13]张永俊,袁岩,何晓峰,等.射频消融联合臭氧联合射频消融治疗神经根型颈椎病的临床效果[J].江苏医药,2016,42(2):181-182.
[14]吴昊,周文来.不同浓度医用臭氧联合射频消融治疗膝关节骨性关节炎的疗效及对TNF-α和IL-6的影响[J].现代中西医结合杂志,2015,24(16):1782-1784.
[15]徐传华.臭氧联合射频消融治疗对神经根型颈椎病患者疼痛及TNF-α的影响[J].免疫学杂志,2014,30(3):274-276.
[16]徐传华,张利君.臭氧对腰椎间盘突出症患者TNF-α和IL-6的影响[J].中华全科医学,2014,12(2):316-317.
[17]于密生,刘志奇,宋建梅,等.颈椎旁与硬膜外阻滞联合臭氧联合射频消融治疗神经根型颈椎病的疗效观察[J].河北医药,2014,36(11):1707-1709.