交泰丸膏穴位贴敷治疗心肾不交型失眠随机平行对照研究
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摘要
[目的]观察交泰丸膏穴位贴敷治疗心肾不交型失眠疗效。[方法]使用随机平行对照方法,将60例住院患者按病志号抽签方法简单随机分为两组。对照组30例艾司唑仑,2mg/次,1次/d,口服。治疗组30例交泰丸膏穴位贴敷(黄连、肉桂、磁石、龙骨、炒酸枣仁、柏子仁,大理州第二人民医院药剂科加工制作成中药膏剂),双侧涌泉、内关、心俞、肾俞,纱布固定每晚睡前贴敷,晨起取下。连续治疗30d为1疗程。观测临床症状、PSQI评分、睡眠影响因子、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组临床痊愈4例,显效9例,有效15例,无效2例,总有效率93.33%;对照组临床痊愈1例,显效7例,有效16例,无效6例,总有效率80.00%;治疗组疗效优于对照组(P<0.05)。PSQI总分、睡眠影响因子评分两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]交泰丸膏穴位贴敷治疗心肾不交型失眠,疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Jiaotai pill acupoint sticking therapy of the insomnia patients which diagnosed with the TCM syndrome(imbalance between heart-Yang and kidney-Yin).[Methods] We employed the randomly contrast study at parallel level, 60 cases of hospitalized patients randomly divided into two groups by drawing lots with the pathography number. The control group, 30 cases of estazolam 2 mg/time, 1/d, oral. Treatment group,30 cases Jiaotai pill(交泰丸) for acupoint sticking(The pharmacy of second people's hospital of Dali prefecture use rhizoma coptidis, cinnamon, magnet, keel, Fried Semen Ziziphi Spinosae, platycladi seed,processed into traditional Chinese medicine ointments), jiaotai pills used at the bilateral yongquan point and neiguan point, hsin shu, shenshu point for acupoint sticking therapy, ointments fixed by gauze before sleeping every night and take down it in the morning. We continue the treatment till 30 d for 1 course. Observe the clinical symptoms, PSQI score, Sleep impact factor, adverse reactions. We judged curative effect after 2 courses of this treatment. [Results] In treatment group, 4 cases were cured, 9 cases have obvious effect,15 cases were useful, only 2 cases were treatment failured, the total efficiency is 93.33%.In the control group 1 case was cured, the markedly effective individuals were 7, 16 cases were useful,6 cases were treatment failured. the total efficiency is 80.00%. Treating group was better than control group(P<0.05). PSQI total score, sleep impact factor scores were improved in the two groups(P<0.01), the treatment group improved better than the control group(P<0.01). [Conclusion]Jiaotai pill paste acupoint sticking therapy for the insomnia patients which diagnosed with the TCM syndrome has satisfactory results and don't have serious adverse reactions. The therapy should be promoted.
[Objective] To observe the curative effect of Jiaotai pill acupoint sticking therapy of the insomnia patients which diagnosed with the TCM syndrome(imbalance between heart-Yang and kidney-Yin).[Methods] We employed the randomly contrast study at parallel level, 60 cases of hospitalized patients randomly divided into two groups by drawing lots with the pathography number. The control group, 30 cases of estazolam 2 mg/time, 1/d, oral. Treatment group,30 cases Jiaotai pill(交泰丸) for acupoint sticking(The pharmacy of second people's hospital of Dali prefecture use rhizoma coptidis, cinnamon, magnet, keel, Fried Semen Ziziphi Spinosae, platycladi seed,processed into traditional Chinese medicine ointments), jiaotai pills used at the bilateral yongquan point and neiguan point, hsin shu, shenshu point for acupoint sticking therapy, ointments fixed by gauze before sleeping every night and take down it in the morning. We continue the treatment till 30 d for 1 course. Observe the clinical symptoms, PSQI score, Sleep impact factor, adverse reactions. We judged curative effect after 2 courses of this treatment. [Results] In treatment group, 4 cases were cured, 9 cases have obvious effect,15 cases were useful, only 2 cases were treatment failured, the total efficiency is 93.33%.In the control group 1 case was cured, the markedly effective individuals were 7, 16 cases were useful,6 cases were treatment failured. the total efficiency is 80.00%. Treating group was better than control group(P<0.05). PSQI total score, sleep impact factor scores were improved in the two groups(P<0.01), the treatment group improved better than the control group(P<0.01). [Conclusion]Jiaotai pill paste acupoint sticking therapy for the insomnia patients which diagnosed with the TCM syndrome has satisfactory results and don't have serious adverse reactions. The therapy should be promoted.
引文
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[11]吴师机.理瀹骈文[M].北京:人民卫生出版社,1955.
[12]马春.中药穴位贴敷治疗失眠的临床观察[J].中国医药指南,2011,14(26):775-776.
[13]殷建权,李立红,严伟,等.穴位贴敷对失眠症改善的临床疗效观察[J].浙江中医药大学学报,2011,22(3):545-546.
[14]赵欣纪.穴位贴敷治疗失眠78例临床观察[J].光明中医,2010,23(8):67-68.
[2]关玲,秦爱梅,蔡兰萍,等.不同失眠症易患群体的睡眠特征比较[J].中国临床康复,2005,48(9):30-32.
[3]吴松涛.引火归元汤治疗不寐39例[J].浙江中医学院学报,2000,24(3):33.
[4]中华人民共和国卫生部.涉及人的生物医学研究伦理审查办法(试行)[S].(2007-03-26)[2014-01-01].http://www.moh.gov.cn/qjjys/s3581/200804/b9f1bfee4ab344ec892e68097296e2a8.shtml
[5]范肖冬.ICD-10精神与行为障碍分类[M].北京:人民卫生出版社,1993:144-145.
[6]中国中医药协会.中医内科常见病诊疗指南中医病证部分[M].北京:中国中医药出版社,2008:46.
[7]刘贤臣,唐茂芹.匹兹堡睡眠质量指数的信度和效度研究[J].中华精神科杂志,1996(2):103-107.
[8]库宝善,庄鸿娟.失眠与睡眠[M].北京:北京医科大学、协和医科大学联合出版社,1993:154-156.
[9]钱彦方.失眠证病因及其中医调治[J].中国临床康复,2006,10(27):139-142.
[10]刘明军,黄莺,于天源,等.中医外治技术[M].北京:中国中医药出版社,2006:29.
[11]吴师机.理瀹骈文[M].北京:人民卫生出版社,1955.
[12]马春.中药穴位贴敷治疗失眠的临床观察[J].中国医药指南,2011,14(26):775-776.
[13]殷建权,李立红,严伟,等.穴位贴敷对失眠症改善的临床疗效观察[J].浙江中医药大学学报,2011,22(3):545-546.
[14]赵欣纪.穴位贴敷治疗失眠78例临床观察[J].光明中医,2010,23(8):67-68.