BNP、HRV和ECG在心律失常诊断中的作用
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摘要
目的探讨B型利钠肽(brain natriuretic peptide,BNP)、心率变异性(heart rate variability,HRV)和心电图(electrocardiogram,ECG)在心律失常诊断中的作用和临床意义。方法选取2015年7月—2017年5月上海市奉贤区中心医院收治的心律失常患者100例为观察组,健康体检者50例为对照组,检测患者24 h内BNP、HRV和ECG的变化情况。结果与对照组比较,心律失常患者体内BNP水平升高,HRV相关指标水平降低,ECG有明显改变,差异具有统计学意义(P<0.05)。且心律失常患者中BNP+HRV+ECG联合检测的阳性率、灵敏度和特异度高于各指标的单独检出结果,差异具有统计学意义(P<0.05)。结论给予心律失常患者BNP、HRV和ECG联合诊断在临床诊断中有重要意义,能够为患者的临床症状和状态评估提供有效可靠的参考依据。
Objective To investigate the role and clinical significance of brain natriuretic peptide(BNP), heart rate variability(HRV) and electrocardiogram(ECG) in the diagnosis of arrhythmia. Methods Between July 2015 and May2017,100 patients with arrhythmia admitted to the Central Hospital of Shanghai were selected as the observation group,while another 50 healthy patients served as the control group. The changes of BNP, HRV and ECG were detected within 24 h.Results Compared with the control group, the level of BNP in patients with arrhythmia was significantly increased, heart rate variability was significantly reduced, and ECG changed significantly. The difference was statistically significant(P<0.05). In addition, the positive rate, sensitivity and specificity of BNP + HRV + ECG combined diagnosis of patients with arrhythmia were significantly higher than those of BNP, HRV and ECG used individually, and the difference was statistically significant(P<0.05). Conclusion The combined diagnosis with BNP, HRV and ECG for patients with arrhythmia is of great significance for clinical diagnosis. It can provide effective and reliable reference for assessment of clinical symptoms and status of patients.
Objective To investigate the role and clinical significance of brain natriuretic peptide(BNP), heart rate variability(HRV) and electrocardiogram(ECG) in the diagnosis of arrhythmia. Methods Between July 2015 and May2017,100 patients with arrhythmia admitted to the Central Hospital of Shanghai were selected as the observation group,while another 50 healthy patients served as the control group. The changes of BNP, HRV and ECG were detected within 24 h.Results Compared with the control group, the level of BNP in patients with arrhythmia was significantly increased, heart rate variability was significantly reduced, and ECG changed significantly. The difference was statistically significant(P<0.05). In addition, the positive rate, sensitivity and specificity of BNP + HRV + ECG combined diagnosis of patients with arrhythmia were significantly higher than those of BNP, HRV and ECG used individually, and the difference was statistically significant(P<0.05). Conclusion The combined diagnosis with BNP, HRV and ECG for patients with arrhythmia is of great significance for clinical diagnosis. It can provide effective and reliable reference for assessment of clinical symptoms and status of patients.
引文
[1]严霞,周丽莉.某院健康体检人群心电图长(短)PR间期发现状况研究[J].检验医学与临床,2017, 14(13):2 000-2 001.
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[5]余升,李善高,李海红.肺炎合并心衰患儿血浆心肌肌钙蛋白与脑钠肽水平的变化情况及其与心功能的关系[J].中国妇幼保健,2015, 30(5):723-725.
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[7]客蕊,王秋琳,姚凤祯.针刺内关穴联合养心汤治疗快速型心律失常(气阴两虚)患者30例[J].针灸临床杂志,2016, 32(7):38-40.
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[9]齐欣,郭书文,陈剑明,等.益气活血法联合酒石酸美托洛尔治疗冠心病心律失常的临床研究[J].中华中医药学刊,2017, 35(2):279-282.
[10]杨毅波,何英泉,杨继超.冠心病心律失常的动态心电图与常规心电图应用对比评价[J].中国医药科学,2015, 5(2):23-25, 39.
[11]黄道花,万红燕,高晓炎.B超引导下应用心电图定位PICC尖端位置的临床研究[J].东南大学学报(医学版),2017, 36(1):107-109.
[12]张颖.12导联动态心电图对无症状心肌缺血的诊断价值[J].临床医学,2014, 34(3):42-43.
[13]于迎根,彭颖秀,史咏秋.慢性心衰患者心率减速力与室性心律失常的相关性研究[J].现代医学,2016, 44(8):1074-1076.
[14]魏文佳.动态心电图在扩张型心肌病植入心室同步化起博-电复律除颤器后的应用研究[J].现代医学,2016, 44(4):508-511.
[2]韩雪,马麟,冯瑞华,等.瑞舒伐他汀联合胺碘酮对ACS伴心律失常的疗效分析[J].检验医学与临床,2017, 14(2):256-258.
[3]赵星,李军.李军教授论颈源性心律失常[J].四川中医,2017, 35(4):2-4.
[4]商丽丽,秦鹏.针刺心包经为主治疗心律失常临床疗效观察[J].四川中医,2016, 34(1):196-197.
[5]余升,李善高,李海红.肺炎合并心衰患儿血浆心肌肌钙蛋白与脑钠肽水平的变化情况及其与心功能的关系[J].中国妇幼保健,2015, 30(5):723-725.
[6]毛志敏,周如丹.MCP-1在炎性反应中的研究进展[J].医学综述,2013, 19(6):964-966.
[7]客蕊,王秋琳,姚凤祯.针刺内关穴联合养心汤治疗快速型心律失常(气阴两虚)患者30例[J].针灸临床杂志,2016, 32(7):38-40.
[8]詹玉飞.高龄急性心肌梗死患者发生早期恶性室性心律失常的相关因素分析[J].心脑血管病防治,2017, 17(4):281-283.
[9]齐欣,郭书文,陈剑明,等.益气活血法联合酒石酸美托洛尔治疗冠心病心律失常的临床研究[J].中华中医药学刊,2017, 35(2):279-282.
[10]杨毅波,何英泉,杨继超.冠心病心律失常的动态心电图与常规心电图应用对比评价[J].中国医药科学,2015, 5(2):23-25, 39.
[11]黄道花,万红燕,高晓炎.B超引导下应用心电图定位PICC尖端位置的临床研究[J].东南大学学报(医学版),2017, 36(1):107-109.
[12]张颖.12导联动态心电图对无症状心肌缺血的诊断价值[J].临床医学,2014, 34(3):42-43.
[13]于迎根,彭颖秀,史咏秋.慢性心衰患者心率减速力与室性心律失常的相关性研究[J].现代医学,2016, 44(8):1074-1076.
[14]魏文佳.动态心电图在扩张型心肌病植入心室同步化起博-电复律除颤器后的应用研究[J].现代医学,2016, 44(4):508-511.