火针联合聚肌胞注射液治疗扁平疣的效果观察
|
摘要
目的探讨火针联合聚肌胞注射液治疗扁平疣的临床疗效。方法随机将90例扁平疣患者分为A、B、C 3组,各30例,A组单用聚肌胞注射治疗,B组单用火针疗法治疗,C组采用火针疗法联合聚肌胞注射治疗。观察3组治疗效果及复发情况。结果 A、B、C 3组治疗有效率分别为70. 00%、80. 00%、100. 00%,C组有效率明显高于B、C 2组(P <0. 05)。治疗后随访3个月,A组8例复发,B组3例复发,C组无患者复发;治疗后随访6个月,A组5例复发,B组2例复发,C组无患者复发。结论火针联合聚肌胞注射液治疗扁平疣治愈率高,复发率低,值得推广。
Objective To investigate the efficacy of fire needle combined with polyinosinicpolycytidylic acid injection in the treatment of flat wart. Methods Totally 90 patients with flat wart were randomly divided into group A,group B and group C,30 cases in each group. The patients in group A were treated with polyinosinic-polycytidylic acid injection alone,those in group B with fire needle alone,and those in group C with combination of fire needle and polyinosinicpolycytidylic acid injection. The therapeutic effect and recurrence condition were observed among three groups. Results The response rates of groups A,B and C were respectively 70. 00%,80. 00% and 10. 00%,and the response rate of group C was significantly higher than those of groups A and B( P < 0. 05). At three months after treatment,there were 8 cases in the group A and 3 cases in the group B diagnosed with recurrence of flat wart. At six months after treatment,there were 5 cases in the group A and 2 cases in the group B diagnosed with recurrence of flat wart. There was no recurrence observed in the group C during follow-up. Conclusion Fire needle combined with polyinosinic-polycytidylic acid injection in the treatment of flat wart has advantages of high cure rate and low recurrence rate,so it deserves to be popularized in clinic.
Objective To investigate the efficacy of fire needle combined with polyinosinicpolycytidylic acid injection in the treatment of flat wart. Methods Totally 90 patients with flat wart were randomly divided into group A,group B and group C,30 cases in each group. The patients in group A were treated with polyinosinic-polycytidylic acid injection alone,those in group B with fire needle alone,and those in group C with combination of fire needle and polyinosinicpolycytidylic acid injection. The therapeutic effect and recurrence condition were observed among three groups. Results The response rates of groups A,B and C were respectively 70. 00%,80. 00% and 10. 00%,and the response rate of group C was significantly higher than those of groups A and B( P < 0. 05). At three months after treatment,there were 8 cases in the group A and 3 cases in the group B diagnosed with recurrence of flat wart. At six months after treatment,there were 5 cases in the group A and 2 cases in the group B diagnosed with recurrence of flat wart. There was no recurrence observed in the group C during follow-up. Conclusion Fire needle combined with polyinosinic-polycytidylic acid injection in the treatment of flat wart has advantages of high cure rate and low recurrence rate,so it deserves to be popularized in clinic.
引文
[1]GAO J,SHEN C,KO R,et al.Combination effect of super pulsed carbon dioxide laser and photodynamic therapy for recalcitrant facial flat warts:A preliminary study[J].J Cosmet Laser Ther,2016,18(1):56-57.
[2]YANG Y L,SANG J J,LIAO N X,et al.Off-label photodynamic therapy for recalcitrant facial flat warts using topic 59 aminolevulinic acid[J].Las Med Sci,2016,31(5):929-936.
[3]黄烨,曹碧兰.中西医治疗扁平疣的研究进展[J].中国医药指南,2015,13(27):35-37.
[4]许岳亭,魏跃钢.中西医结合治疗颜面部扁平疣34例临床观察[J].江苏中医药,2018,50(2):37-39.
[5]国家中医药管理局.中医皮肤科病证诊断疗效标准[M].北京:人民卫生出版社,2003:15.
[6]阮仁杰.自制中药倒膜联合火针治疗面部扁平疣60例疗效观察[J].中国中西医结合皮肤性病学杂志,2017,16(3):245-246.
[7]王元秋,赵庆平,薛朝先.368例扁平疣治疗回顾性调查分析[J].医学信息,2014,27(6):460-461.
[8]祁原婷.火针治疗扁平疣90例[J].云南中医中药杂志,2013,34(12):98.
[9]丁军青,叶晓红,许功军.5-氨基酮戊酸光动力疗法联合针刺治疗面部多发性扁平疣疗效观察[J].中国中西医结合皮肤性病学杂志,2015,14(1):37-38.
[10]HATTORI M,SHIMIZU A,KAIRA K,et al.Atypical flat warts in an immunocompromised patient[J].J Dermatol,2017,44(4):473-474.
[11]CHARNY J W,RADY P L,TYRING S K,et al.Malignant degeneration of diffuse intertriginous flat warts in a patient with AIDS[J].JAAD Case Rep,2018,4(6):562-564.
[12]CACCAVALE S,CACCAVALE T,LA MONTAGNAM.Facial flat warts in a young patient with a previous trauma:an example of isotraumatopic response[J].Int J Dermatol,2016,55(10):e568-e569.
[13]温泽发,李润生,张英小.蜂针疗法联合聚肌胞注射液穴位注射对带状疱疹后遗神经痛患者血清T细胞亚群的影响[J].中国中医急症,2018,27(1):47-50.
[2]YANG Y L,SANG J J,LIAO N X,et al.Off-label photodynamic therapy for recalcitrant facial flat warts using topic 59 aminolevulinic acid[J].Las Med Sci,2016,31(5):929-936.
[3]黄烨,曹碧兰.中西医治疗扁平疣的研究进展[J].中国医药指南,2015,13(27):35-37.
[4]许岳亭,魏跃钢.中西医结合治疗颜面部扁平疣34例临床观察[J].江苏中医药,2018,50(2):37-39.
[5]国家中医药管理局.中医皮肤科病证诊断疗效标准[M].北京:人民卫生出版社,2003:15.
[6]阮仁杰.自制中药倒膜联合火针治疗面部扁平疣60例疗效观察[J].中国中西医结合皮肤性病学杂志,2017,16(3):245-246.
[7]王元秋,赵庆平,薛朝先.368例扁平疣治疗回顾性调查分析[J].医学信息,2014,27(6):460-461.
[8]祁原婷.火针治疗扁平疣90例[J].云南中医中药杂志,2013,34(12):98.
[9]丁军青,叶晓红,许功军.5-氨基酮戊酸光动力疗法联合针刺治疗面部多发性扁平疣疗效观察[J].中国中西医结合皮肤性病学杂志,2015,14(1):37-38.
[10]HATTORI M,SHIMIZU A,KAIRA K,et al.Atypical flat warts in an immunocompromised patient[J].J Dermatol,2017,44(4):473-474.
[11]CHARNY J W,RADY P L,TYRING S K,et al.Malignant degeneration of diffuse intertriginous flat warts in a patient with AIDS[J].JAAD Case Rep,2018,4(6):562-564.
[12]CACCAVALE S,CACCAVALE T,LA MONTAGNAM.Facial flat warts in a young patient with a previous trauma:an example of isotraumatopic response[J].Int J Dermatol,2016,55(10):e568-e569.
[13]温泽发,李润生,张英小.蜂针疗法联合聚肌胞注射液穴位注射对带状疱疹后遗神经痛患者血清T细胞亚群的影响[J].中国中医急症,2018,27(1):47-50.