痤疮中医辨证分型与生活质量的相关性研究
|
摘要
目的通过对痤疮患者生活质量的调查,探讨不同证型痤疮患者生活质量的差异,以期为临床中医诊疗提供理论依据。方法本研究采用国际通用的Skindex-16、皮肤病生活质量指数(DLQI)两种生活质量量表对300例痤疮患者进行测评。根据中医辨证分型进行分组,肺经风热证110例、肠胃湿热证101例、痰凝血瘀证89例。对两种量表测评所得结果比较各组的总分及各维度得分情况。结果痤疮患者Skindex-16及DLQI量表总分分别为(43.19±21.71)分和(8.83±6.73)分。痰凝血瘀证组Skindex-16量表及DLQI量表总分最高,肠胃湿热证组次之,肺经风热证组最低,两两组间分值差异有统计学意义(P <0.01)。Skindex-16量表各维度评分显示,肺经风热证组与肠胃湿热证组、肺经风热证组与痰凝血瘀证组在症状、情感、功能维度的分值差异有统计学意义(P <0.01);肠胃湿热证组与痰凝血瘀证组在症状维度的分值差异有统计学意义(P <0.01)。DLQI量表各维度评分显示,肺经风热证组与肠胃湿热证组、肺经风热证组与痰凝血瘀证组在症状、感受、日常生活、娱乐活动、工作学习、社交、治疗维度的分值差异有统计学意义(P <0.01);肠胃湿热证组与痰凝血瘀证组在症状、日常生活、娱乐活动维度上的分值差异有统计学意义(P <0.01,P <0.05)。结论痤疮患者的生活质量属中等以上,不同证型间痤疮生活质量存在差异,痰凝血瘀证患者生活质量最差,肠胃湿热证次之,肺经风热证较好,痤疮患者的中医辨证分型与生活质量存在一定联系。
Objective To discuss the correlation of acne patients' life quality with different traditional Chinese medicine(TCM) syndrome types of acne to provide theoretical basis for acne diagnosis and treatment. Methods Based on TCM syndrome differentiation 300 acne patients were measured and divided into 110 cases of lung meridian wind-heat syndrome, 101 cases of intestine-stomach dampness-heat syndrome and 89 cases of phlegm-coagulation blood stasis syndrome. Two internationally recognized life quality scales(Skindex-16, DLQI) were used to assess. The results of two scales were compared with the total scores and the scores of each dimension in each group. Results The total score of Skindex-16 scale was 43.19±21.71.The total score of DLQI was 8.83±6.73. Between the Skindex-16 scale and the DLQI scale,the phlegm-coagulation blood stasis syndrome group gained the highest scores,the intestine-stomach dampness-heat syndrome group comes second, and the lowest was the lung meridian wind-heat syndrome group. There was a statistically significant difference between these groups(P<0.01). The Skindex-16 scores of each dimension showed that there were statistically significant differences in the scores of symptoms, emotions and functional dimensions between the two groups: the lung meridian wind-heat syndrome group and the intestine-stomach dampness-heat syndrome group, the lung meridian wind-heat syndrome group and the phlegm-coagulation blood stasis syndrome group(P<0.01). The scores of symptoms between the intestine-stomach dampness-heat syndrome group and the phlegm-coagulation blood stasis syndrome group were statistically significant(P<0.01). The DLQI scores of each dimension showed that there were statistically significant differences in the scores of symptoms, feelings, daily life, entertainments, work-study, social events and treatment between the two groups: the lung meridian wind-heat syndrome group and the intestine-stomach dampness-heat syndrome group, the lung meridian windheat syndrome group and the phlegm-coagulation blood stasis syndrome group(P<0.01). The scores of symptoms,daily life and entertainments between the intestine-stomach dampness-heat syndrome group and the phlegm-coagulation blood stasis syndrome group were statistically significant(P<0.01, P<0.05). Conclusion The life quality of acne patients is generally above moderate. There are differences in life quality among different acne types. The quality of life in the patients with phlegm-coagulation blood stasis syndrome is the worst, that of intestine-stomach dampness-heat syndrome is second, and that of lung meridian wind-heat syndrome is better. There is a certain relationship between TCM syndrome differentiation and quality of life in acne patients.
Objective To discuss the correlation of acne patients' life quality with different traditional Chinese medicine(TCM) syndrome types of acne to provide theoretical basis for acne diagnosis and treatment. Methods Based on TCM syndrome differentiation 300 acne patients were measured and divided into 110 cases of lung meridian wind-heat syndrome, 101 cases of intestine-stomach dampness-heat syndrome and 89 cases of phlegm-coagulation blood stasis syndrome. Two internationally recognized life quality scales(Skindex-16, DLQI) were used to assess. The results of two scales were compared with the total scores and the scores of each dimension in each group. Results The total score of Skindex-16 scale was 43.19±21.71.The total score of DLQI was 8.83±6.73. Between the Skindex-16 scale and the DLQI scale,the phlegm-coagulation blood stasis syndrome group gained the highest scores,the intestine-stomach dampness-heat syndrome group comes second, and the lowest was the lung meridian wind-heat syndrome group. There was a statistically significant difference between these groups(P<0.01). The Skindex-16 scores of each dimension showed that there were statistically significant differences in the scores of symptoms, emotions and functional dimensions between the two groups: the lung meridian wind-heat syndrome group and the intestine-stomach dampness-heat syndrome group, the lung meridian wind-heat syndrome group and the phlegm-coagulation blood stasis syndrome group(P<0.01). The scores of symptoms between the intestine-stomach dampness-heat syndrome group and the phlegm-coagulation blood stasis syndrome group were statistically significant(P<0.01). The DLQI scores of each dimension showed that there were statistically significant differences in the scores of symptoms, feelings, daily life, entertainments, work-study, social events and treatment between the two groups: the lung meridian wind-heat syndrome group and the intestine-stomach dampness-heat syndrome group, the lung meridian windheat syndrome group and the phlegm-coagulation blood stasis syndrome group(P<0.01). The scores of symptoms,daily life and entertainments between the intestine-stomach dampness-heat syndrome group and the phlegm-coagulation blood stasis syndrome group were statistically significant(P<0.01, P<0.05). Conclusion The life quality of acne patients is generally above moderate. There are differences in life quality among different acne types. The quality of life in the patients with phlegm-coagulation blood stasis syndrome is the worst, that of intestine-stomach dampness-heat syndrome is second, and that of lung meridian wind-heat syndrome is better. There is a certain relationship between TCM syndrome differentiation and quality of life in acne patients.
引文
[1]Lukaviciute L,Navickas P.Quality of life,anxiety prevalence,depression symptomatology and suicidal ideation among acne patients in Lithuania[J].J Eur Acad Dermatol Venereol,2017,31(11):1900-1906.
[2]赵辨.中国临床皮肤病学[M].南京:江苏科学技术出版社,2009:1165-1166.
[3]郑筱萸.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:292-296.
[4]陈红风.中医外科学2版[M].北京:人民卫生出版社,2012:235-235.
[5]张仲昭.简体中文版Skindex-29和Skindex-16的建立和文化调适及信效度评价[D].广州:广州中医药大学,2013:52-52.
[6]贾淑琳,范瑞强,禤国维,等.国医大师禤国维教授滋阴清热法治疗痤疮理论探讨[J].南京中医药大学学报,2016,32(3):207-209.
[7]沈冬,刘瓦利.庄国康治疗痤疮经验[J].中医杂志,2001,42(4):210-210.
[8]马绍尧,李咏梅.当代中医皮肤科临床家丛书-马绍尧[M].北京:中国医药科技出版社,2014:53-55.
[9]闫小宁,李争红.当代中医皮肤科临床家丛书-韩世荣[M].北京:中国医药科技出版社,2015:181-191.
[10]张天博,白彦萍.寻常痤疮的中医证候研究进展[J].江苏中医药,2018,50(12):83-86.
[11]杨岚,李元文,曲剑华.痤疮辨证分型的文献研究[J].北京中医药,2015,34(6):472-473.
[2]赵辨.中国临床皮肤病学[M].南京:江苏科学技术出版社,2009:1165-1166.
[3]郑筱萸.中药新药临床研究指导原则[S].北京:中国医药科技出版社,2002:292-296.
[4]陈红风.中医外科学2版[M].北京:人民卫生出版社,2012:235-235.
[5]张仲昭.简体中文版Skindex-29和Skindex-16的建立和文化调适及信效度评价[D].广州:广州中医药大学,2013:52-52.
[6]贾淑琳,范瑞强,禤国维,等.国医大师禤国维教授滋阴清热法治疗痤疮理论探讨[J].南京中医药大学学报,2016,32(3):207-209.
[7]沈冬,刘瓦利.庄国康治疗痤疮经验[J].中医杂志,2001,42(4):210-210.
[8]马绍尧,李咏梅.当代中医皮肤科临床家丛书-马绍尧[M].北京:中国医药科技出版社,2014:53-55.
[9]闫小宁,李争红.当代中医皮肤科临床家丛书-韩世荣[M].北京:中国医药科技出版社,2015:181-191.
[10]张天博,白彦萍.寻常痤疮的中医证候研究进展[J].江苏中医药,2018,50(12):83-86.
[11]杨岚,李元文,曲剑华.痤疮辨证分型的文献研究[J].北京中医药,2015,34(6):472-473.