植物多酚及其提取方法的研究进展
|
摘要
多酚类物质是一类含有多个酚羟基并具有多种生物学活性的次生代谢产物,广泛分布于植物中。由于其具有抗氧化、降血压、抗肿瘤等多种健康效应,从植物中提取多酚受到广泛关注和研究。因此,本文重点对植物多酚的分类、提取方法及各方法的优缺点进行综述,旨在为后续植物多酚的研究积累资料,同时为植物的进一步开发和利用提供参考。
Polyphenols,which are widely distributed in plants and possess many biological activities,are a class of secondary metabolites with multiple phenolic hydroxyl groups.Polyphenols extracted from plants have aroused great attention because of its various bioactivies,such as antioxidant activity,anti-hypertension and anti-tumor.Therefore,in this paper,the classification,extraction methods and advantages and disadvantages of plant polyphenols were summarized for further research and utilization.
Polyphenols,which are widely distributed in plants and possess many biological activities,are a class of secondary metabolites with multiple phenolic hydroxyl groups.Polyphenols extracted from plants have aroused great attention because of its various bioactivies,such as antioxidant activity,anti-hypertension and anti-tumor.Therefore,in this paper,the classification,extraction methods and advantages and disadvantages of plant polyphenols were summarized for further research and utilization.
引文
[1]唐春红.天然防腐剂与抗氧化剂[M].北京:中国轻工业出版社,2010.
[2]李静,赵海峰.多酚类化合物的主要食物来源[J].卫生研究,2017,46(1):169-172.
[3]Zhang X M,Liu Y G,Zhu Z Y,et al. Total polyphenols,flavonoids and antioxidant activities in mulberry(Morus alba)leaves and fruit at different maturities[J]. Journal of Fruit Science,2014,31(4):660-666.
[4]Rigacci S. Olive oil phenols as promising multi-targeting agents against Alzheimer’s disease[M]//Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases. Springer International Publishing,2015:1.
[5]Martin D A,Bolling B W.A review of the efficacy of dietary polyphenols in experimental models of inflammatory bowel diseases[J].Food&Function,2015,6(6):1773-1786.
[6]SlobodníkováL,FialováS,RendekováK,et al. Antibiofilm activity of plant polyphenols[J].Molecules,2016,21(12):1717.
[7]Moore J,Yousef M,Tsiani E.Anticancer effects of posemary(Rosmarinus officinalis L.)extract and rosemary extract polyphenols[J].Nutrients,2016,8(11):731.
[8]Varoni E M,Faro A F L,Sharifirad J,et al. Anticancer molecular mechanisms of resveratrol[J]. Frontiers in Nutrition,2016,3(Suppl):82-83.
[9]Cardona F,Andrés-Lacueva C,Tulipani S,et al.Benefits of polyphenols on gut microbiota and implications in human health[J].Journal of Nutritional Biochemistry,2013,24(8):1415.
[10]Tangney C C,Rasmussen H E. Polyphenols,inflammation,and cardiovascular disease[J]. Current Atherosclerosis Reports,2013,15(5):324.
[11]Bagchi D,Bagchi M,Stohs S J,et al.Free radicals and grape seed proanthocyanidin extract:Importance in human health and disease prevention[J].Toxicology,2000,148(2-3):187.
[12]Fantini M,Benvenuto M,Masuelli L,et al.In vitro and in vivo antitumoral effects of combinations of polyphenols,or polyphenols and anticancer drugs:Perspectives on cancer treatment[J].International Journal of Molecular Sciences,2015,16(5):9236-9282.
[13]Yokota J,Takuma D,Hamada A,et al.Scavenging of reactive oxygen species by Eriobotrya japonica seed extract[J]. Biological&Pharmaceutical Bulletin,2006,29(3):467.
[14]于帅,杜彬,杨越冬,等.植物中多酚的研究进展[J].河北科技师范学院学报,2011,25(3):68-74.
[15]王振宇,孔子浩,孔令华,等.天然多酚提取、分离及鉴定方法的研究进展[J].保鲜与加工,2017(4):113-120.
[16]刘继攀,李佳欢,张紫华,等.真姬菇水溶性多酚的提取及抗氧化活性研究[J].中国食品添加剂,2018(1):110-118.
[17]C'ujic'N,avikin K,Jankovi c'T,et al. Optimization of polyphenols extraction from dried chokeberry using maceration as traditional technique[J]. Food Chemistry,2016,194(5):135-142.
[18]阮景军,韦小宝,严俊,等.响应面法优化黄秋葵总酚超声提取工艺及抗氧化活性[J].中国瓜菜,2017,30(12):9-14.
[19]齐娜,李涵,张志宇,等.新疆红肉苹果多酚的超声波辅助提取工艺优化[J].食品与机械,2016,32(9):177-182.
[20]D’Alessandro L G,Kriaa K,Nikov I,et al. Ultrasound assisted extraction of polyphenols from black chokeberry[J].Separation&Purification Technology,2012(93):42-47.
[21]高磊,李慧芸.微波辅助提取核桃青皮中多酚的工艺研究[J].农产品加工,2017(15):26-28.
[22]周芳,赵鑫,宫婕,等.响应面法优化微波辅助提取红皮云杉多酚工艺[J].食品工业科技,2014,35(10):210-213.
[23]Galan A M,Calinescu I,Trifan A,et al.New insights into the role of selective and volumetric heating during microwave extraction:Investigation of the extraction of polyphenolic compounds from sea buckthorn leaves using microwave-assisted extraction and conventional solvent extraction[J]. Chemical Engineering&Processing Process Intensification,2017.2017.03.006
[24]李康,王希希,崔晓瑞,等.红树莓多酚提取物闪式提取工艺优化及其抗氧化性[J].食品工业科技,2018,39(5):197-201.
[25]巫永华,刘恩岐,张建萍,等.黄精多酚的闪式提取及抗氧化活性研究[J].食品科技,2017(8):231-236.
[26]张宇,苏丹.二氢槲皮素提取方法的比较和优化[J].中医学报,2015,30(10):1470-1472.
[27]Zhang J,Jia S,Liu Y,et al.Optimization of enzyme-assisted extraction of the Lycium barbarum,polysaccharides using response surface methodology[J]. Carbohydrate Polymers,2011,86(2):1089-1092.
[28]王华斌,王珊,傅力.酶法提取石榴皮多酚工艺研究[J].中国食品学报,2012,12(6):56-65.
[29]屈文秀,刁小琴,汪春玲,等.响应面优化酶法辅助乙醇提取马铃薯皮渣多酚工艺[J/OL].保鲜与加工,2018(1):1-9.
[30]唐頊婉,张晓旭,陈思锐,等.大孔树脂吸附法分离八月瓜果皮总多酚[J].广东化工,2015,42(16):40-42.
[31]符智荣,李雪峰,欧阳玉祝,等.大孔吸附树脂分离葛根总多酚的工艺条件优化[J].化学与生物工程,2015(10):25-28.
[32]叶俭慧,梁月荣.大孔吸附树脂分离茶多酚的研究[J].茶叶,2006,32(3):128-132.
[33]冯务群,李辉,等.4种方法提取石榴皮中没食子酸的比较[J].中医药导报,2008,14(8):16-17.
[34]尹志芳,钟桐生,彭晓赟,等.黑茶中茶多酚及咖啡碱的超临界CO2流体萃取研究[J].湖南城市学院学报:自然科学版,2012(3):56-59.
[35]卢沿钢,董全.高压脉冲电场提取食品中天然产物的研究进展[J].食品与机械,2012,28(1):243-246.
[36]殷涌光,闫琳娜,陶柳.高压脉冲电场法提取干松针总黄酮及其体外抗氧化性检测[J].天然产物研究与开发,2009,21(6):1032-1035.
[37]唐守勇,王文渊,张芸兰,等.竹叶中黄酮和茶多酚的高压脉冲电场提取[J].中国食物与营养,2014(12):50-53.
[38]Wang W.Study on extraction of tea-polyphenols in bamboo leaf and its antioxidational effect[J]. Flavour Fragrance Cosmetics,2011.
[39]Chen Y.Study on extraction of flavones from bamboo leaf by microwave radition[J].Food Engineering,2011.
[40]徐树来,金慧荣,任红波,等.酶解-超声组合提取蒲公英中绿原酸的工艺优化[J].食品工业科技,2018,39(8):160-166.
[41]李立顺,时维静,方婷,等.多种提取方法比较野生与栽培蒲公英绿原酸含量[J].中兽医医药杂志,2007(6):24-26.
[42]倪悦,徐达,孙强,等.蒲公英绿原酸的酶法提取及其在卷烟中的应用[J].安徽农业科学,2016,44(17):107-110.
[43]王文渊,周振华,黄宁江,等.高压脉冲电场协同酶法提取竹叶中活性成分的研究[J].中国食品添加剂,2014(6):95-101.
[2]李静,赵海峰.多酚类化合物的主要食物来源[J].卫生研究,2017,46(1):169-172.
[3]Zhang X M,Liu Y G,Zhu Z Y,et al. Total polyphenols,flavonoids and antioxidant activities in mulberry(Morus alba)leaves and fruit at different maturities[J]. Journal of Fruit Science,2014,31(4):660-666.
[4]Rigacci S. Olive oil phenols as promising multi-targeting agents against Alzheimer’s disease[M]//Natural Compounds as Therapeutic Agents for Amyloidogenic Diseases. Springer International Publishing,2015:1.
[5]Martin D A,Bolling B W.A review of the efficacy of dietary polyphenols in experimental models of inflammatory bowel diseases[J].Food&Function,2015,6(6):1773-1786.
[6]SlobodníkováL,FialováS,RendekováK,et al. Antibiofilm activity of plant polyphenols[J].Molecules,2016,21(12):1717.
[7]Moore J,Yousef M,Tsiani E.Anticancer effects of posemary(Rosmarinus officinalis L.)extract and rosemary extract polyphenols[J].Nutrients,2016,8(11):731.
[8]Varoni E M,Faro A F L,Sharifirad J,et al. Anticancer molecular mechanisms of resveratrol[J]. Frontiers in Nutrition,2016,3(Suppl):82-83.
[9]Cardona F,Andrés-Lacueva C,Tulipani S,et al.Benefits of polyphenols on gut microbiota and implications in human health[J].Journal of Nutritional Biochemistry,2013,24(8):1415.
[10]Tangney C C,Rasmussen H E. Polyphenols,inflammation,and cardiovascular disease[J]. Current Atherosclerosis Reports,2013,15(5):324.
[11]Bagchi D,Bagchi M,Stohs S J,et al.Free radicals and grape seed proanthocyanidin extract:Importance in human health and disease prevention[J].Toxicology,2000,148(2-3):187.
[12]Fantini M,Benvenuto M,Masuelli L,et al.In vitro and in vivo antitumoral effects of combinations of polyphenols,or polyphenols and anticancer drugs:Perspectives on cancer treatment[J].International Journal of Molecular Sciences,2015,16(5):9236-9282.
[13]Yokota J,Takuma D,Hamada A,et al.Scavenging of reactive oxygen species by Eriobotrya japonica seed extract[J]. Biological&Pharmaceutical Bulletin,2006,29(3):467.
[14]于帅,杜彬,杨越冬,等.植物中多酚的研究进展[J].河北科技师范学院学报,2011,25(3):68-74.
[15]王振宇,孔子浩,孔令华,等.天然多酚提取、分离及鉴定方法的研究进展[J].保鲜与加工,2017(4):113-120.
[16]刘继攀,李佳欢,张紫华,等.真姬菇水溶性多酚的提取及抗氧化活性研究[J].中国食品添加剂,2018(1):110-118.
[17]C'ujic'N,avikin K,Jankovi c'T,et al. Optimization of polyphenols extraction from dried chokeberry using maceration as traditional technique[J]. Food Chemistry,2016,194(5):135-142.
[18]阮景军,韦小宝,严俊,等.响应面法优化黄秋葵总酚超声提取工艺及抗氧化活性[J].中国瓜菜,2017,30(12):9-14.
[19]齐娜,李涵,张志宇,等.新疆红肉苹果多酚的超声波辅助提取工艺优化[J].食品与机械,2016,32(9):177-182.
[20]D’Alessandro L G,Kriaa K,Nikov I,et al. Ultrasound assisted extraction of polyphenols from black chokeberry[J].Separation&Purification Technology,2012(93):42-47.
[21]高磊,李慧芸.微波辅助提取核桃青皮中多酚的工艺研究[J].农产品加工,2017(15):26-28.
[22]周芳,赵鑫,宫婕,等.响应面法优化微波辅助提取红皮云杉多酚工艺[J].食品工业科技,2014,35(10):210-213.
[23]Galan A M,Calinescu I,Trifan A,et al.New insights into the role of selective and volumetric heating during microwave extraction:Investigation of the extraction of polyphenolic compounds from sea buckthorn leaves using microwave-assisted extraction and conventional solvent extraction[J]. Chemical Engineering&Processing Process Intensification,2017.2017.03.006
[24]李康,王希希,崔晓瑞,等.红树莓多酚提取物闪式提取工艺优化及其抗氧化性[J].食品工业科技,2018,39(5):197-201.
[25]巫永华,刘恩岐,张建萍,等.黄精多酚的闪式提取及抗氧化活性研究[J].食品科技,2017(8):231-236.
[26]张宇,苏丹.二氢槲皮素提取方法的比较和优化[J].中医学报,2015,30(10):1470-1472.
[27]Zhang J,Jia S,Liu Y,et al.Optimization of enzyme-assisted extraction of the Lycium barbarum,polysaccharides using response surface methodology[J]. Carbohydrate Polymers,2011,86(2):1089-1092.
[28]王华斌,王珊,傅力.酶法提取石榴皮多酚工艺研究[J].中国食品学报,2012,12(6):56-65.
[29]屈文秀,刁小琴,汪春玲,等.响应面优化酶法辅助乙醇提取马铃薯皮渣多酚工艺[J/OL].保鲜与加工,2018(1):1-9.
[30]唐頊婉,张晓旭,陈思锐,等.大孔树脂吸附法分离八月瓜果皮总多酚[J].广东化工,2015,42(16):40-42.
[31]符智荣,李雪峰,欧阳玉祝,等.大孔吸附树脂分离葛根总多酚的工艺条件优化[J].化学与生物工程,2015(10):25-28.
[32]叶俭慧,梁月荣.大孔吸附树脂分离茶多酚的研究[J].茶叶,2006,32(3):128-132.
[33]冯务群,李辉,等.4种方法提取石榴皮中没食子酸的比较[J].中医药导报,2008,14(8):16-17.
[34]尹志芳,钟桐生,彭晓赟,等.黑茶中茶多酚及咖啡碱的超临界CO2流体萃取研究[J].湖南城市学院学报:自然科学版,2012(3):56-59.
[35]卢沿钢,董全.高压脉冲电场提取食品中天然产物的研究进展[J].食品与机械,2012,28(1):243-246.
[36]殷涌光,闫琳娜,陶柳.高压脉冲电场法提取干松针总黄酮及其体外抗氧化性检测[J].天然产物研究与开发,2009,21(6):1032-1035.
[37]唐守勇,王文渊,张芸兰,等.竹叶中黄酮和茶多酚的高压脉冲电场提取[J].中国食物与营养,2014(12):50-53.
[38]Wang W.Study on extraction of tea-polyphenols in bamboo leaf and its antioxidational effect[J]. Flavour Fragrance Cosmetics,2011.
[39]Chen Y.Study on extraction of flavones from bamboo leaf by microwave radition[J].Food Engineering,2011.
[40]徐树来,金慧荣,任红波,等.酶解-超声组合提取蒲公英中绿原酸的工艺优化[J].食品工业科技,2018,39(8):160-166.
[41]李立顺,时维静,方婷,等.多种提取方法比较野生与栽培蒲公英绿原酸含量[J].中兽医医药杂志,2007(6):24-26.
[42]倪悦,徐达,孙强,等.蒲公英绿原酸的酶法提取及其在卷烟中的应用[J].安徽农业科学,2016,44(17):107-110.
[43]王文渊,周振华,黄宁江,等.高压脉冲电场协同酶法提取竹叶中活性成分的研究[J].中国食品添加剂,2014(6):95-101.